An NCI-designated Comprehensive Cancer Center
Ke Ma

Ke Ma, M.D., Ph.D.

Associate Professor, Department of Diabetes Complications and Metabolism
Research Focus
  • Circadian clock regulation of metabolism
  • Circadian clock-controlled epigenetic mechanisms
  • Adipose tissue growth and metabolic capacity
  • Skeletal muscle development, growth and remodeling
Other Languages Spoken
  • Mandarin

Research Teams

  • Diabetes Complications and Metabolism
Ke Ma, M.D., Ph.D., has a long-standing dedicated interest in metabolic disease research. Following her medical training from Shandong Medical University with an M.D. degree, Dr. Ma pursued doctoral studies in lipoprotein metabolism and cardiovascular disease research at Baylor College of Medicine. Her subsequent postdoctoral research at the Department of Molecular and Cellular Biology led to one of the leading studies on the metabolic benefit of the bile acid receptor FXR in improving glucose homeostasis, and a molecular link she discovered between the circadian clock network and bile acid metabolism.
This innovative work garnered her the prestigious AstraZeneca Diabetes and Metabolism Research Fellow Award from the Endocrine Society. Dr. Ma established a successful independent research on circadian clock control of metabolism as a tenure-track assistant member at the Center for Diabetes Research at the Houston Methodist Research Institute prior to her recruitment to City of Hope.
She is currently an associate professor of the Department of Diabetes Complications and Metabolism within the Diabetes & Metabolism Research Institute at City of Hope. Her current research are supported by multiple grants from the American Heart Association, Muscular Dystrophy Association, and National Institute of Diabetes and and Digestive and Kidney Diseases. Dr. Ma has served as reviewers for many scientific journals including Cell Reports and Diabetes. She has served on the grant review panel for the American Heart Association since 2012.


City of Hope Comprehensive Cancer Center, 1500 East Duarte Road

Duarte, CA 91010

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