Markus Kalkum, Ph.D., is co-director of the Mass Spectrometry and Proteomics Core at City of Hope. His research areas include mass spectrometry, microbiology and immunology. In particular, he employs mass spectrometry and proteomics to develop novel diagnostic assays and vaccines. This includes developing mass spectrometric methods for the quantitative analysis of proteins and other molecules in complex biological samples. He is generating novel biochemical assays for the ultrasensitive detection of functional biomolecules.
His goal is to improve the early diagnosis and prevention of emerging and of frequently underdiagnosed diseases, including opportunistic fungal and bacterial infections. He is advancing mycosis vaccine development and is studying immunomodulatory compounds of the gut microbiome. These activities are aimed at protecting cancer patients from opportunistic infections, improving cancer treatment outcomes.
Education & Experience
1999, Dr. rer. nat. (Ph.D. equivalent) in Chemistry, Biology, Pharmacy, Freie Universität Berlin, Germany
1995, Diploma in Chemistry, Universität Konstanz, Germany
2018-present, Professor, Department of Immunology & Theranostics, Arthur Riggs Diabetes Metabolism Research Institute, City of Hope, Duarte, CA
2014-2018, Professor, Department of Molecular Immunology, Beckman Research Institute of City of Hope, Duarte, CA
2009-2014, Associate Professor, Department of Molecular Immunology, Beckman Research Institute of City of Hope, Duarte, CA
2003-2009, Assistant Professor, Department of Molecular Immunology, Beckman Research Institute of City of Hope, Duarte, CA
2000-2003, Postdoctoral Scientist at Dr. Brian Chait’s lab, The Rockefeller University, New York
1999-2000, Postdoctoral Scientist, Max-Planck-Institute for Molecular Genetics, Mass Spectrometry group of Dr. H. Lehrach, Berlin
1995-1999, Max Planck for Institute for Molecular Genetics, Department of Dr. H. Lehrach, Berlin