
City of Hope is a global leader in breast cancer research, treatment and prevention. Our breast cancer physician scientists are highly specialized experts focusing on one type of disease, which allows them to bring the latest treatments from the laboratory to the patient’s bedside with lifesaving speed. The multidisciplinary teams that lead the care of each patient with breast cancer at City of Hope Orange County deliver leading-edge treatment through groundbreaking evidence-based research, on-site clinical trials, and comprehensive and personalized care for each patient.
Our subspecialized breast cancer team offers fellowship-level expertise and is committed to work in partnership with regional physicians for patient-centered care and quality outcomes. Hope is where life wins and cancer loses.
Physician Referral Fax: 949-777-6750
From screening mammograms to more in-depth diagnostics, providing a comprehensive imaging and screening center with pathology and biopsy capabilities.
- Breast MRI
- Breast ultrasound
- Digital breast tomosynthesis (mammogram)
- Physical exam
- Second opinion services for abnormal screenings
- Undiagnosed breast mass clinic
Offering state-of-the-art germline and tumor genetic testing to study and consider the molecular and cellular features of a tumor. We then collaborate with a clinical genetics team to develop a customized treatment.
- Blood tests
- Genetic counseling
- Genetic testing (e.g. BRCA1, BRCA2)
Offering a wide portfolio of cancer-fighting drugs, from chemotherapy and targeted therapy to immunotherapy and endocrine therapy, to best fight breast cancer while minimizing side effects. Our infusion centers and centralized care bring together access and convenience.
- Chemotherapy
- Hormone therapy
- Immunotherapy
- Targeted therapy
- Angiogenesis inhibitors
- Chemopreventive therapy
Combining experienced radiation oncologists with advanced technology to provide patients access to radiation therapy and interoperative radiation therapy to optimize outcomes.
- Intensity-Modulated Radiation Therapy (IMRT)
- Stereotactic Body Radiotherapy (SBRT)
- High-Dose-Rate (HDR) Brachytherapy
- Volumetric Modulated Arc Therapy (VMAT)
- Deep Inspiratory Breath Hold (DIBH)
- Respiratory gating
- TRUEBEAM® BY VARIAN
- Respiration-synchronized MV/KV radiographs
- 4D CBCT
- Iterative CBCT
- Triggered Imaging
- Coming soon will include:
- Four-Dimensional Computed (4D CT) Scanning
- ETHOS® By Varian
- MRIdian® MR Linac By ViewRay
City of Hope has radiologists dedicated to breast imaging and interventional radiologists who specialize in providing compassionate, patient-centered care using the most advanced equipment available.
- Core needle biopsy
- Stereotactic biopsy
- Ultrasound-guided biopsy
- MRI-guided biopsy
A specialized surgical team brings patients the latest techniques for treating breast cancer, including minimally invasive approaches, breast-conserving surgery and reconstructive surgery.
While surgery is often only one part of treatment, we lead the way in innovative and thoughtful surgical approaches to treating breast cancer and strive to take a minimally invasive approach to reduce discomfort, hasten recovery time and allow for patients to proceed with postsurgical treatments sooner.
Patients have access to a wide range of innovative surgical approaches, including but not limited to:
- Lumpectomy using latest guidance techniques
- Skin and nipple-sparing mastectomy
- Oncoplastic surgery
- Direct-to-implant postmastectomy breast reconstruction surgery
- Complex, autologous (tissue-based) breast reconstruction surgery
- Prophylactic surgery
- Axillary lymph node dissection
- Lymphovenous bypass
Nationally recognized supportive care services and programs helping patients and their families ease the physical, emotional and psychological burdens of a life-changing diagnosis., including social work, support groups, integrative medicine, and physical medicine and rehabilitation.
- Hope Boutique (oncology-trained cosmetologists)
- Integrative medicine
- Lymphedema therapy
- Nutrition counseling
- Pain management
- Palliative care, hospice
- Physical medicine and rehabilitation
- Physical and occupational therapy
- Scalp cooling systems
Physician Resources
City of Hope Orange County Lennar Foundation Cancer Center Breast Screening & Diagnostic Center Referring Physician Order Form.
We're here to help and welcome the opportunity to partner with you in providing your patients with the latest treatment innovations.
City of Hope Orange County's expertise in infusion therapy extends beyond cancer-relates drugs. We also administer non-oncology medications.
For more information about our comprehensive breast cancer program, or to schedule a one-on-one with a City of Hope cancer expert, please contact one of our physicians.
Our nationally recognized oncologists, radiation oncologists, interventionalists, supportive medicine specialists and surgical teams are all highly regarded for their innovation and utilization of the most advanced treatment techniques. Our clinicians across our Orange County network develop and improve evidence-based treatment guidelines to offer the best choice for breast cancer care in the region.


Medical Director, Breast Surgery


Medical Director, Women's Health Medical Oncology
SURGICAL ONCOLOGY
Hang T. Dang, D.O.
Surgical Oncology
MAMMOGRAPHY
Jennifer Chen, M.D.
Radiology
RADIATION ONCOLOGY
Amanda Schwer, M.D.
Radiation Oncology
PLASTICS & RECONSTRUCTIVE SURGERY
Mouchammed Agko, M.D.
Plastic & Reconstructive Surgery
MEDICAL ONCOLOGY
Wade Smith, M.D.
Medical Oncology
Mohamad Barakat, M.D.
Hematology & Medical Oncology
Luke Chen, M.D.
Hematology & Medical Oncology
Sassan Farjami, M.D.
Hematology & Medical Oncology
Dilruba Haque, M.D.
Hematology & Medical Oncology
Yaser Homsi, M.D.
Hematology & Medical Oncology
Sudarsan Kollimuttathuillam, M.D.
Hematology & Medical Oncology
Andre K.D. Liem, M.D.
Hematology & Medical Oncology
Aileen Z. Novero, M.D.
Hematology & Medical Oncology
Sarmen Sarkissian, M.D.
Hematology & Medical Oncology
George Semeniuk, M.D.
Hematology & Medical Oncology
Nishan Tchekmedyian, M.D.
Hematology & Medical Oncology
Rodina Vatanparast, M.D.
Hematology & Medical Oncology
Lihong Wu, M.D.
Hematology & Medical Oncology
SUPPORTIVE CARE
Richard Lee, M.D.
Supportive Care Medicine/Integrative Medicine
Jessica Chen, M.D.
Physical Medicine and Rehabilitation
City of Hope believes that patients benefit from a collaboration between us and their referring physicians. We work in partnership with you, communicating with you frequently, and focusing on helping patients return to your care when they complete their treatment. Learn more about our programs and services.