Terence Williams Lab Publications

  • Deregulation of AKT-mTOR Signaling Contributes to Chemoradiation Resistance in Lung Squamous Cell Carcinoma. Shen C, Shyu DL, Xu M, Yang L, Webb A, Duan W, Williams TM. Mol Cancer Res. 2021 Nov 22:molcanres.0272.2021. doi: 10.1158/1541-7786.MCR-21-0272. Online ahead of print.

  • Narrative review of emerging roles for AKT-mTOR signaling in cancer radioimmunotherapy. Shen C, He Y, Chen Q, Feng H, Williams TM, Lu Y, He Z. Ann Transl Med. 2021 Oct;9(20):1596. doi: 10.21037/atm-21-4544. PMID: 34790802 

  • Development of a MicroRNA Signature Predictive of Recurrence and Survival in Pancreatic Ductal Adenocarcinoma. Sebastian NT, Webb A, Merrell KW, Koay EJ, Wolfe AR, Zhang L, Wilhite TJ, Elganainy D, Robb R, Chen W, Cloyd J, Dillhoff M, Tsung A, Abushahin L, Noonan A, Williams TM. Cancers (Basel). 2021 Oct 15;13(20):5168. doi: 10.3390/cancers13205168. PMID: 34680317 

  • Cardiac radioablation in the treatment of ventricular tachycardia. Siedow M, Brownstein J, Prasad RN, Loccoh E, Harfi TT, Okabe T, Tong MS, Afzal MR, Williams T. Clin Transl Radiat Oncol. 2021 Feb 12;31:71-79. doi: 10.1016/j.ctro.2021.02.005. eCollection 2021 Nov. PMID: 34646951 

  • Oncogenic KRAS drives radioresistance through upregulation of NRF2-53BP1-mediated non-homologous end-joining repair. Yang L, Shen C, Estrada-Bernal A, Robb R, Chatterjee M, Sebastian N, Webb A, Mo X, Chen W, Krishnan S, Williams TM. Nucleic Acids Res. 2021 Nov 8;49(19):11067-11082. doi: 10.1093/nar/gkab871. PMID: 34606602 

  • A novel protein-drug conjugate, SSH20, demonstrates significant efficacy in caveolin-1-expressing tumors. Robb R, Kuo JC, Liu Y, Corrales-Guerrero S, Cui T, Hegazi A, Nagy G, Lee RJ, Williams TM. Mol Ther Oncolytics. 2021 Aug 6;22:555-564. doi: 10.1016/j.omto.2021.07.013. eCollection 2021 Sep 24. PMID: 34553040 

  • BRAF mutation correlates with worse local-regional control following radiation therapy in patients with stage III melanoma. Wolfe AR, Chablani P, Siedow MR, Miller ED, Walston S, Kendra KL, Wuthrick E, Williams TM. Radiat Oncol. 2021 Sep 18;16(1):181. doi: 10.1186 s13014-021-01903-5. PMID: 34537078

  • Stereotactic body radiation therapy in advanced NSCLC. Williams TM. Clin Adv Hematol Oncol. 2021 Jul;19(7):439-441. PMID: 34236342 

  • Disparate Use of Chemoradiation in Elderly Patients With Localized Anal Cancer. Miller ED, Nalin AP, Diaz Pardo DA, Arnett AL, Huang E, Gasior AC, Malalur P, Chen HZ, Williams TM, Bazan JG. J Natl Compr Canc Netw. 2021 Jun 10:1-9. doi: 10.6004/jnccn.2020.7691. Online ahead of print. PMID: 34111839

  • Non-Small-Cell Lung Cancer Regression by siRNA Delivered Through Exosomes That Display EGFR RNA Aptamer. Li Z, Yang L, Wang H, Binzel DW, Williams TM, Guo P. Nucleic Acid Ther. 2021 Oct;31(5):364-374. doi: 10.1089/nat.2021.0002. Epub 2021 May 17. PMID: 33999716

  • Pharmacological Regulation of Tumor Hypoxia in Model Murine Tumors and Spontaneous Canine Tumors. Benej M, Wu J, Kreamer M, Kery M, Corrales-Guerrero S, Papandreou I, Williams TM, Li Z, Graves EE, Selmic LE, Denko NC. Cancers (Basel). 2021 Apr 3;13(7):1696. doi: 10.3390/cancers13071696. PMID: 33916656 

  • Global Phosphoproteomics Reveal CDK Suppression as a Vulnerability to KRas Addiction in Pancreatic Cancer. Kazi A, Chen L, Xiang S, Vangipurapu R, Yang H, Beato F, Fang B, Williams TM, Husain K, Underwood P, Fleming JB, Malafa M, Welsh EA, Koomen J, Trevino J, Sebti SM. Clin Cancer Res. 2021 Jul 15;27(14):4012-4024. doi: 10.1158/1078-0432.CCR-20-4781. Epub 2021 Apr 20. PMID: 33879459

  • Predictors of Response, Progression-Free Survival, and Overall Survival in Patients With Lung Cancer Treated With Immune Checkpoint Inhibitors. Memmott RM, Wolfe AR, Carbone DP, Williams TM. J Thorac Oncol. 2021 Jul;16(7):1086-1098. doi: 10.1016/j.jtho.2021.03.017. Epub 2021 Apr 9. PMID: 33845212

  • Method and Atlas to Enable Targeting for Cardiac Radioablation Employing the American Heart Association Segmented Model. Brownstein J, Afzal M, Okabe T, Harfi TT, Tong MS, Thomas E, Hugo G, Cuculich P, Robinson C, Williams TM. Int J Radiat Oncol Biol Phys. 2021 Sep 1;111(1):178-185. doi: 10.1016/j.ijrobp.2021.03.051. Epub 2021 Apr 6. PMID: 33836242

  • Regulation of DNA duplication by the mTOR signaling pathway. He Z, Houghton PJ, Williams TM, Shen C. Cell Cycle. 2021 Apr;20(8):742-751. doi: 10.1080/15384101.2021.1897271. Epub 2021 Mar 10. PMID: 33691584

  • Increasing neutrophil-to-lymphocyte ratio following radiation is a poor prognostic factor and directly correlates with splenic radiation dose in pancreatic cancer. Wolfe AR, Siedow M, Nalin A, DiCostanzo D, Miller ED, Diaz DA, Arnett A, Cloyd JM, Dillhoff M, Ejaz A, Tsung A, Williams TM. Radiother Oncol. 2021 May;158:207-214. doi: 10.1016/j.radonc.2021.02.035. Epub 2021 Mar 3. PMID: 33667588

  • Neoadjuvant therapy versus surgery first for ampullary carcinoma: A propensity score-matched analysis of the NCDB. Guo M, Beal EW, Miller ED, Williams TM, Tsung A, Dillhoff M, Ejaz A, Pawlik TM, Cloyd JM. J Surg Oncol. 2021 Jun;123(7):1558-1567. doi: 10.1002/jso.26435. Epub 2021 Feb 17. PMID: 33596343

  • MYBL2-Driven Transcriptional Programs Link Replication Stress and Error-prone DNA Repair With Genomic Instability in Lung Adenocarcinoma. Morris BB, Wages NA, Grant PA, Stukenberg PT, Gentzler RD, Hall RD, Akerley WL, Varghese TK, Arnold SM, Williams TM, Coppola V, Jones DR, Auble DT, Mayo MW. Front Oncol. 2021 Jan 8;10:585551. doi: 10.3389/fonc.2020.585551. eCollection 2020. PMID: 33489883 

  • Potential Molecular Targets in the Setting of Chemoradiation for Esophageal Malignancies. Jabbour SK, Williams TM, Sayan M, Miller ED, Ajani JA, Chang AC, Coleman N, El-Rifai W, Haddock M, Ilson D, Jamorabo D, Kunos C, Lin S, Liu G, Prasanna PG, Rustgi AK, Wong R, Vikram B, Ahmed MM. J Natl Cancer Inst. 2021 Jun 1;113(6):665-679. doi: 10.1093/jnci/djaa195. PMID: 33351071 

  • EMT-Induced Gemcitabine Resistance in Pancreatic Cancer Involves the Functional Loss of Equilibrative Nucleoside Transporter 1. Weadick B, Nayak D, Persaud AK, Hung SW, Raj R, Campbell MJ, Chen W, Li J, Williams TM, Govindarajan R. Mol Cancer Ther. 2021 Feb;20(2):410-422. doi: 10.1158/1535-7163.MCT-20-0316. Epub 2020 Dec 9. PMID: 33298588
     

To view all publications, please visit NCBI link here.