An NCI-designated Comprehensive Cancer Center

Christiane Querfeld, M.D., Ph.D.

Dermatologist/Dermatopathologist
Clinical Expertise
Research Focus
  • Tumor microenvironment in cutaneous lymphoma
Appointments
Chief, Division of Dermatology; Director, Cutaneous Lymphoma Program, Toni Stephenson Lymphoma Center; Associate Professor, Department of Surgery
Other Languages Spoken
  • French
  • German
At the end of the day, it is always about helping patients get better so they can go on to continue living normal lives.
 
Christiane Querfeld, M.D., Ph.D., is a dermatologist and dermatopathologist who specializes in the diagnosis and treatment of cutaneous lymphoma, a rare form of lymphoma which first appears on the skin but can also spread to lymph nodes and internal organs (City of Hope is one of the few institutions in the country that currently offer clinical trials available to help treat cutaneous lymphomas.)
 
Dr. Querfeld received her medical degree at University of Cologne and a Ph.D. at University of Heidelberg. She then received additional training at Johns Hopkins University, University of Chicago and Northwestern University, specializing in dermatopathology and cutaneous lymphoma diagnosis and treatment.
 
Following her training, Dr. Querfeld worked in the dermatology department at Memorial Sloan Kettering Cancer Center in New York City before joining City of Hope’s Toni Stephenson Lymphoma Center in 2014.
 
A recognized authority in the field, Dr. Querfeld has published over 80 scholarly articles on cutaneous lymphoma.

Locations

City of Hope Comprehensive Cancer Center, 1500 East Duarte Road

Duarte, CA 91010

Querfeld C, Leung S, Myskowski PL, Curran SA, Goldman DA, Heller G, Wu X, Kil SH, Sharma S, Finn K, Mehrara B, Horwitz S, Moskowitz A, Rosen ST, Halpern AC, Young JW. Primary T-cells from cutaneous T-cell lymphoma skin explants display an exhausted immune checkpoint profile. Cancer Immunol Res. 2018. DOI: 10.1158/2326-6066.CIR-17-0270.

Marchetti MA, Pulitzer MP, Myskowski PL, Lunning MA, Dusza SW, Horwitz SM, Moskowitz AJ, Querfeld C. Cutaneous manifestations of human T-cell lymphotrophic virus type-1-associated adult T-cell leukemia/lymphoma: a single-center, retrospective study. J Am Acad Dermatol (accepted for publication), 2014.

Querfeld C, Rosen ST, Guitart J, Duvic M, Kim YH, Dusza SW, Kuzel TM. Results of an open-label multicenter phase II trial of lenalidomide monotherapy in refractory mycosis fungoides and Sézary syndrome. Blood 123(8): 1159-1166, 2014.

Jawed SI, Myskowski PL, Horwitz S, Moskowitz A, Querfeld C. Primary Cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome) Part II. Prognosis, management, and future directions. J Am Acad Dermatol 70(2): 223.e1-17; quiz 240-2, 2014.

Jawed SI, Myskowski PL, Horwitz S, Moskowitz A, Querfeld C. Primary cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome) Part I. Diagnosis: Clinical and histopathologic features, and new molecular and biologic markers. J Am Acad Dermatol 70(2): 205.e1-16; quiz 221-2, 2014.

Pulitzer M, Myskowski MP, Horwitz S, Querfeld C, Li J, Murali R. Mycosis fungoides with large cell transformation: clinicopathological features and prognostic factors. Pathology 46(7): 610-616, 2014.

Li JY, Guitart J, Pulitzer M, Subtil A, Sundram U, Kim YH, Deonizio J, Myskowski PL, Moskowitz A, Horwitz S, Querfeld C. Multicenter case series of indolent small/medium-sized CD8+ lymphoid proliferations with predilection for the ear and face. Am J Dermatopathol 36(5): 402-408, 2014.

Li JY, Pulitzer M, Myskowski PL, Dusza SW, Horwitz S, Moskowitz A, Querfeld C. A case-control study of clinicopathologic features, prognosis, and therapeutic responses in patients with granulomatous mycosis fungoides. J Am Acad Dermatol 69(3): 366-374.e4, 2013.

Knobler R, Duvic M, Querfeld C, Straus D, Horwitz S, Zain J, Foss F, Kuzel TM, Campbell K, Geskin L. Long-term follow-up and survival of cutaneous T-cell lymphoma patients treated with extracorporeal photopheresis. Photodermatol Photoimmunol Photomed 28(5): 250-257, 2012.

Thomas TO, Agrawal P, Guitart J, Rosen ST, Rademaker AW, Querfeld C, Hayes JP, Kuzel TM, Mittal BB. Outcome of patients with a single-fraction dose of palliative radiation for cutaneous T-cell lymphoma. Int J Radiat Oncol Biol Phys 85(3):747-53, 2013.

Li JY, Horwitz S, Moskowitz A, Myskowski PL, Pulitzer M, Querfeld C. Management of cutaneous T-cell lymphoma: new and emerging targets and treatment options. Cancer Manag Res 4: 75-89, 2012.

Querfeld C, Rosen ST, Guitart J, Rademaker A, Pezen DS, Dolan E, Baron J, Yarosh DB, Foss F, Kuzel TM. Multicenter phase II trial of temozolomide in mycosis fungoides/Sézary syndrome: correlation with O6-methylguanine-DNA methyltransferase and mismatch repair proteins. Clin Cancer Res 17(17): 5748-5754, 2011.

Querfeld C, Kuzel TM, Kim YH, Porcu P, Duvic M, Musiek A, Rook AH,  Mark LA, Pinter-Brown L, Hamid O, Lin B, Bian Y, Boye M, Day JM, Rosen ST. Multicenter phase II trial of enzastaurin in patients with relapsed or refractory advanced cutaneous T-cell lymphoma. Leuk Lymph 52(8): 1474-1480, 2011.

Olsen EA, Rook AH, Zic J, Kim Y, Porcu P, Querfeld C, Wood G, Demierre MF, Pittelkow M, Wilson L, Pinter-Brown L, Advani R, Parker S, Kim E, Junkins-Hopkins J, Foss F, Cacchio P, Duvic M. Sézary Syndrome: evaluation, immuno-pathogenesis, literature review of therapeutic options and recommendations for therapy by the United States Cutaneous Lymphoma Consortium (USCLC). J Am Acad Dermatol 64(2): 352-404, 2011.

Gerami P, Wickless SC, Querfeld C, Rosen ST, Kuzel TM, Guitart J. Cutaneous involvement with marginal zone lymphoma. J Am Acad Dermatol 63(1): 142-145, 2010.

Querfeld C, Khan I, Mahon B, Nelson BP, Rosen ST, Evens AM. Primary cutaneous and systemic anaplastic large cell lymphoma: clinicopathologic aspects and therapeutic options. Oncology (Williston Park) 24(7): 574-587, 2010.

Querfeld C, Mehta N, Rosen ST, Guitart J, Rademaker A, Gerami P, Kuzel TM. Alemtuzumab for relapsed and refractory erythrodermic cutaneous T-cell lymphoma: a single center experience from the Robert H. Lurie Comprehensive Cancer Center. Leuk Lymph 50(12): 1969-1976, 2009.

Querfeld C, Rosen ST, Guitart J, Rademaker A, Foss F, Gupka R, Kuzel TM. Phase II trial of subcutaneous injections of human recombinant interleukin-2 for the treatment of mycosis fungoides and Sézary syndrome. J Am Acad Dermatol 56(4): 580-3, 2007.

Querfeld C, Kuzel TM, Guitart J, Rizvi M, Sabharwal SS, Krett N, Rosen ST. The selective protein kinase C ? inhibitor enzastaurin induces apoptosis in cutaneous T-cell lymphoma cell lines through the AKT pathway. J Invest Dermatol 126(7): 1641-7, 2006.

Querfeld C, Rosen ST, Kuzel TM, Kirby KA, Roenigk HH Jr, Prinz BM, Guitart J. Long-term follow-up of patients with early stage cutaneous T-cell lymphoma who achieved complete remission on psoralen plus UV-A monotherapy. Arch Dermatol 141(3): 305-11, 2005.

Querfeld C, Rosen ST, Guitart J, Rademaker A, Fung SB, Posten W, Kuzel TM. Comparison of selective RAR and RXR retinoid mediated efficacy, tolerance, and survival in refractory cutaneous T-cell lymphoma. J Am Acad Dermatol 51(1): 25-32, 2004.

This is a list of 21 representative publications (selected from 81 publications).

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