An NCI-designated Comprehensive Cancer Center

Dortha Chu, M.D., Ph.D.

Breast Surgeon; Surgical Oncologist
Clinical Expertise
Assistant Clinical Professor, Division of Surgical Oncology, Department of Surgery
Mission Hills Patients: 818-660-4700

Clinical Teams

Dortha Chu, M.D., Ph.D., specializes in breast cancer surgery and strongly advocates early and regular screenings for all women. She received her medical and doctoral degrees from Washington University School of Medicine in St. Louis, and completed her general surgery training at University of California San Diego.

A native of the Bay Area, Dr. Chu joins City of Hope after eight years at Mercy Merced Community Hospital in Merced, California, where she was chair of the Department of Surgery.

As a child of immigrants, Dr. Chu recalls how difficult it was for her parents to access proper health care because of language and cultural barriers. As a physician, she’s witnessed similar challenges among the disadvantaged. She is committed to “ensuring that all patients are given the same up-to-date and comprehensive care regardless of their race, gender, religious affiliation, sexual orientation or economic status.“


23823 Valencia Blvd., Suite 250

Santa Clarita, CA 91355

15031 Rinaldi St., Suite 150

Mission Hills, CA 91345

  • Scalzo, AA, Brown, MG, Chu, DT, Heusel, JT, Yokoyama, WM, Forbes, CA. Development of intra-natural killer complex (NKC) recombinant and congenic mouse strains for mapping and functional analysis of NK cell regulatory loci. Immunogenetics. 1999. 49: 238-241. 
  • Wang, LL, Chu, DT, Dokun, AO, Yokoyama, WM. Inducible expression of the gp49B inhibitory receptor on NK cells. Journal of Immunology. 2000. 164: 5215-5220. 
  • Dokun, AO, Kim, SJ Smith, HRC, Kang, HS, Chu, DT, Yokoyama, WM. Specific and nonspecific NK cell activation during virus infection. Nature Immunology. 2001. 2(10): 951-956. 
  • Dokun, AO, Chu, DT, Yang, L, Bendelac, AS, Yokoyama, WM. Analysis of in situ NK cell responses during viral infections. 2001. Journal of Immunology. 167: 5286-5293. 
  • Loh, J, Chu, DT, O’Guin, AK, Yokoyama, WM, Virgin, HW 4th. Natural killer cells utilize both perforin and gamma interferon to regulate murine cytomegalovirus infection in the spleen and liver. 2005. Journal of Virology. 79(1): 661-667.
In The News
An Expert's Voice
Dortha Chu - Profile Photo

Custom Care: Personalized Treatment for Breast Cancer