An NCI-designated Comprehensive Cancer Center

Richard Ermel, D.V.M., Ph.D.

Director and Professor, Division of Comparative Medicine
Research Focus
  • Comparative Medicine
Director, Animal Resources Core

Research Teams

  • Comparative Medicine

Richard W. Ermel directs and oversees the Division of Comparative Medicine biomedical and translational research programs.


City of Hope Comprehensive Cancer Center, 1500 East Duarte Road

Duarte, CA 91010

  • Chomel, B.B., Ermel, R.W., Kasten, R.W., Henn, J.B., Fleischman, D.A., Chang, C. Experimental infection of dogs with various Bartonella species or subspecies isolated from their natural reservoir. Vet. Microbiol. 2013 (accepted).
  • Satheseesan, S., Figarola, J., Dabbs, T., Rahbar, S., Ermel, R.W.  Effects of a new advanced glycation inhibitor, LR-90, on mitigating arterial stiffening and improving arterial elasticity and compliance in a diabetic rat model: aortic impedance analysis.  British J. Pharmacol. 2013 (submitted).
  • Samineni, S., Ermel, R.W.  Using research animals as sentinels: Consider the purpose.  Lab. Animal 42 (9):317-318,  2013.
  • Jonnalagadda, M., Ermel, R.W.  Reactivation of a suspended protocol: Do it by policy.  Lab Animal 41 (9):250, 2012.
  • Samineni, S., Ermel, R.W.  From “Designated Member” back to “Full Committee”: Not to late for FCR.  Lab Animal 40 (1):11-12, 2011.
  • Putta, S., Adamson, T., Ermel, R.  Noncompliance in survival surgery technique: Report to OLAW.  Lab Animal 39 (8):234-235, 2010.
  • Jonnalagadda, M., Ermel, R.W.  Multiple campuses, one IACUC: Campus AVs plus an institutional veterinarian.  Lab Animal 38 (4):113-114, 2009.
  • Oki, G.S.F., Ermel, R.W., Whitson, R.H.  Clinical care or protocol violation: Clinical scoring system and pilot study.  Lab Animal 38 (1):8, 2009.
  • Helm, R.M., Ermel, R.W., Frick, O.L.  Non-murine animal models of food allergy.  Environ. Health Persp. 111:239-244, 2003.
  • Guo, J., Zhang, Z., Edwards, J.F., Ermel, R.W., Taylor, Jr., C., de la Concha-Bermejillo.  Characterization of a North American orf virus isolated from a goat with persistent, proliferative dermatitis.  Virus Res. 93:169-179, 2003.
  • de la Concha-Bermejillo, A., Kasari, E.M., Russell, K.E., Cron, L.E., Browder, E.J., Callicott, R., Ermel, R.W.  Q fever: An overview.  Proc. 105th Annual Meeting U.S. Animal Health Assoc.  pp. 391-414, 2002.
  • de la Concha-Bermejillo, A., Ermel, R.W., Zhang, Z., Guo, J.  Contagious ecthyma (orf) virulence factors and vaccine failure.  Proc. U.S. Animal Health Assoc. Annual Meeting, San Diego, CA.  pp. 513-524, 2000.
  • Ermel, R.W.  LAS Journal Club Commentary: Q fever. Lab. Anim. Sci.49(5):474 475, 1999.
  • del Val, G., Yee, B.C., Lozano, R.M., Buchanan, B.B., Ermel, R.W., Lee, Y.M., Frick, O.L.  Thioredoxin treatment increases digestibility and lowers allergencity of milk.  J. Allergy & Clin. Immunol. 103(4):690-697, 1999.
  • Ermel, R.W., Kenny, T.P., Wong, A., Chen, P.P., Malyj, W., Robbins, D.L.  Analysis of the molecular basis of synovial rheumatoid factors in rheumatoid arthritis. Clin. Immuno. Immunopathol.  84:307-317, 1997.
  • Ermel, R.W.  Rodent parvoviruses:  A brief review.  Animal Technology  48(1):17 26, 1997.
  • Rodriguez, J.L., Ermel, R.W., Kenny, T.P., Brooks, D.L., DaMassa, A.J.  Polymerase chain reaction and restriction endonuclease digestion for selected members of the "Mycoplasma mycoides cluster" and Mycoplasma putrefaciens.  J. Vet. Diagn. Invest.  9:186 190, 1997.
  • Buchanan, B.B., Adamidi, C., Lozano, R.M., Yee, B.C., Momma, M., Kobrehel, K., Ermel, R., Frick, O.L.  Thioredoxin linked mitigation of allergic responses to wheat.  Proc. Natl. Acad. Sci. USA  94:5372 5377, 1997. 
  • Ermel, R.W., Kock, M., Griffey, S.M., Reinhart, G.A., Frick, O.L.  The atopic dog:  A model for food allergy.  Lab. Anim. Sci.47(1):40 49, 1997.
  • Buchanan, B.B., Monma, M., Lozano, R., Yee, B.C., Kobrehel, Frick, O.L., Ermel, R.W.  Reduction of allergenicity in plant foods by thioredoxin.  Plant Physiol. 108:150, 1995.
  • Lozano, R., Buchanan, B.B., Frick, O.L., Yee, B.C., Ermel, R.W., Monma, M.  Reduction of allergenicity in foods by thioredoxin.  Allergy, Suppl.26, Vol.50:347,1995.
  • Wong, A., Kenny, T., Ermel, R., Robbins, D.  IgG3 reactive rheumatoid factor in rheumatoid arthritis: Etiologic and pathogenic considerations.  Autoimmunity 19:199 210, 1994.
  • Ermel, R.W., Kenny, T.P., Wong, A., Solomon, A., Chen, P.P., Robbins, D.L.  Preferential utilization of a novel Vl3 gene in monoclonal rheumatoid factors derived from the rheumatoid synovial cells of rheumatoid arthritis patients.  Arth. Rheum. 37(6):860 868, 1994.
  • Wong, A., Kenny, T., Ermel, R., Robbins, D.  Human monoclonal rheumatoid factor derived from rheumatoid synovial cells monospecific for rabbit IgG.  J. Rheumatol. 20(4):623 629, 1993.
  • Robbins, D.L., Kenny, T.P., Synder, L.L., Ermel, R.W., Larrick, J.W.  Allotypic dependency of the specificity and avidity of human monoclonal IgM rheumatoid factors derived from rheumatoid synovial cells.  Arth. Rheum. 36(3):389 393, 1993.
  • Ermel, R.W., Kenny, T.P., Chen, P.P., Robbins, D.L.  Molecular analysis of rheumatoid synovial rheumatoid factors suggests an antigen driven response in inflamed joints.  Arth. Rheum. 36(3):380 388, 1993.
  • Ermel, R., Kenny, T., Benisek, W., Roberts, M., Robbins, D.  Allotype dependent stimulation of T lymphocytes and rheumatoid factor production by IgG3 in rheumatoid arthritis.  Clin. Immuno. Immunopathol. 63(3):259 266, 1992.
  • Tenorio, E., Ermel, R., Giri, S., Brooks, D.  Caprine arthritis encephalitis virus (CAEV) infection in goats as a model for rheumatoid arthritis.  Lab Animal 21:33 36, 1992.
  • McGinn, M.D., Bean Knudsen, D.E., Ermel, R.W.  Incidence of chronic otitis media in CBA/J and CBA/CaJ mice.  Hearing Research 59:1 6, 1992.
  • Brooks, D.L., Ermel, R.W., Franti, C.E., Ruppanner, R., Behymer, D.E., Williams, J.C., Stephenson, J.C.  Q fever vaccination of sheep: Challenge of immunity in ewes.  Am. J. Vet. Res. 47(6):1235 1238, 1986.
  • Mariassy, A., Brooks, D., Ruppanner, R., Ermel, R., Behymer, D., Moore, P.  Coxiella burnetti infection in sheep: Ultrastructural observations of the placenta.  In Rickettsiae`and Rickettsial Diseases.  J. Kazar, Ed.  Bratislava, Slovak Academy of Sciences, 1985, pp. 318 324.
  • Ruppanner, R., Brooks, D.L., Behymer, D.E., Ermel, R.W.  C. burnetti infections in ewes: Will vaccination prevent shedding in exposed animals?  In The Contribution of Laboratory Animal Science to the Welfare of Man and Animals: Past, Present and Future.  J. Archibald, J. Ditchfield, H.C. Rowsell, Eds.  New York, Gustav Eizcher Verlag, 1985, pp. 85 88.
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