Experimental Therapeutics - Angelina Iniguez

Angelina Iniguez, M.Sc.

  • Research Associate II, Department of Experimental Therapeutics

Angelina Iniguez, M.Sc.

Areas of Expertise
  • DNA cloning
  • Southern blot
  • Transformation
  • Recombinant protein expression
  • Protein purification
  • Protein crystallization
  • Western blot
  • 2013-2016, Staff Research Assistant I, Department of Molecular Biology and Biochemistry, University of California, Irvine, CA
  • 2007-2013, Laboratory Assistant, Department of Molecular Biology and Biochemistry, University of California, Irvine, CA
  • 2006-2007, Graduate Research Assistant, Molecular Biology, Genetics and Biochemistry Program, University of California, Irvine, CA
  • 2004-2006, Graduate Research Assistant, Department of Biology, California State University of Los Angeles, CA
  • 2003-2004, Laboratory Assistant, Celmed BioSciences Inc., Los Angeles, CA

Degrees

  • 2006, California State University of Los Angeles, CA, M.Sc. in Biology
  • 2002, California State University of Los Angeles, CA, B.S. in Biology
  • Balderas MA, Nguyen C, Terwilliger A, Keitel WA, Iniguez A, Torres R, Palacios F, Goulding CW, Maresso AW. Progress Towards the Development of a NEAT Protein Vaccine for Anthrax Disease. Infect Immun. 2016 Sep 19. pii: IAI.00755-16. [Epub ahead of print]
  • Morse RP, Willett JL, Johnson PM, Zheng J, Credali A, Iniguez A, Nowick JS, Hayes CS, Goulding CW. Diversification of β-Augmentation Interactions between CDI Toxin/Immunity Proteins. J Mol Biol. 2015 Nov 20;427(23):3766-84. doi: 10.1016/j.jmb.2015.09.020. Epub 2015 Oct 9.
  • Graves AB, Morse RP, Chao A, Iniguez A, Goulding CW, Liptak MD. Crystallographic and spectroscopic insights into heme degradation by Mycobacterium tuberculosis MhuD. Inorg Chem. 2014 Jun 16;53(12):5931-40. doi: 10.1021/ic500033b. Epub 2014 Jun 5.
  • Beck CM, Morse RP, Cunningham DA, Iniguez A, Low DA, Goulding CW, Hayes CS. CdiA from Enterobacter cloacae delivers a toxic ribosomal RNase into target bacteria. Structure. 2014 May 6;22(5):707-18. doi: 10.1016/j.str.2014.02.012. Epub 2014 Mar 20.
  • Owens CP, Chim N, Graves AB, Harmston CA, Iniguez A, Contreras H, Liptak MD, Goulding CW. The Mycobacterium tuberculosis secreted protein Rv0203 transfers heme to membrane proteins MmpL3 and MmpL11. J Biol Chem. 2013 Jul 26;288(30):21714-28. doi: 10.1074/jbc.M113.453076. Epub 2013 Jun 11.
  • Tullius MV, Harmston CA, Owens CP, Chim N, Morse RP, McMath LM, Iniguez A, Kimmey JM, Sawaya MR, Whitelegge JP, Horwitz MA, Goulding CW. Discovery and characterization of a unique mycobacterial heme acquisition system. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5051-6. doi: 10.1073/pnas.1009516108. Epub 2011 Mar 7.
  • Chim N, Iniguez A, Nguyen TQ, Goulding CW. Unusual diheme conformation of the heme-degrading protein from Mycobacterium tuberculosis. J Mol Biol. 2010 Jan 22;395(3):595-608. doi: 10.1016/j.jmb.2009.11.025. Epub 2009 Nov 14.
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