Jana Portnow

Jana Portnow, M.D.

  • Associate Clinical Professor, Department of Medical Oncology & Therapeutics
  • Associate Director, Brain Tumor Program
  • Medical Oncologist

Jana Portnow, M.D.

Clinical Specialties
  • Medical Oncology
  • Neuro-oncology
Areas of Expertise
  • Neuro-oncology
Research Focus
  • Neurologic Oncology
Jana Portnow, M.D., is an associate clinical professor in the Department of Medical Oncology & Therapeutics Research.
 
Dr. Portnow earned her undergraduate degree at Brown University and her medical degree from University of Rochester School of Medicine. She completed her internal medicine residency at Temple University Hospital, where she was chosen to do an additional year of teaching and administration as a chief resident. She then completed fellowships in oncology and neuro-oncology at Johns Hopkins Medical Center before joining the faculty at City of Hope in 2002.
 
She is associate director of City of Hope's Brain Tumor Program and clinical leader of the neural stem cell brain tumor research program. Nationally, she serves as vice-chairperson of the National Comprehensive Cancer Network Guidelines Panel for CNS Cancers, and she reviews grant applications as a member of the National Institute of Health (NIH) Clinical Oncology Study Section.
 
Her research interests include early drug development, with an emphasis on understanding if new chemotherapies can cross the blood-brain barrier and achieve sufficient concentrations in the brain. She has expertise in performing early phase clinical trials of cellular therapies and is currently the principal investigator of a first-in-human study of genetically modified neural stem cells in patients with recurrent high grade gliomas, as well as a first-in-human study of CAR T cells for the treatment of brain metastases.
 
Dr. Portnow has numerous peer-reviewed publications and has received research funding from the NIH/National Cancer Institute, U.S. Food and Drug Administration, California Institute of Regenerative Medicine and Phase One Foundation.
  • 2002 - present, Associate Clinical Professor, Department of Medical Oncology & Therapeutics Research, City of Hope, Duarte, CA
  • 2002 - present, Associate Director, Brain Tumor Program, City of Hope, Duarte, CA
  • 2010 - present, Member, City of Hope Physician Well-being Committee
  • 2004 - present, Member, City of Hope Patient Rights and Organizational Ethics Committee
  • 2010 - 2012 - Chair, City of Hope Data and Safety Monitoring Board
  • 2010 - 2012, Member, Clinical Research Governance Board
  • 2008 - 2010 Associate Chair, City of Hope Data & Safety Monitoring Committee

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1500 East Duarte Road, Duarte, CA, 91010

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Phone :  626-256-4673

Degrees

  • 1994 - M.D.,University of Rochester School of Medicine, Rochester, NY
  • 1989 - B.A., Psychology, Brown University, Providence, RI

Fellowship

  • 1999 -2002, Medical Oncology Fellow, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, Baltimore, MD
  • 1998 -1999, Neuro-Oncology Fellow, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, Baltimore, MD

Residency

  • 1997 -1998, Chief Resident, Department of Internal Medicine, Temple University Hospital, Philadelphia, PA
  • 1994 -1997, Resident, Internal Medicine, Temple University Hospital, Philadelphia, PA
  • 2012, 2001 Medical Oncology
  • 2002, State of California
  • 1997, Internal Medicine

Information listed here is obtained from Pubmed, a public database; City of Hope is not responsible for its accuracy.

Brown CE, Badie B, Barish ME, Weng L, Ostberg JR, Chang WC, Naranjo A, Starr R, Wagner J, Wright C, Zhai Y, Bading JR, Ressler JA, Portnow J, D'Apuzzo M, Forman SJ, Jensen MC.
Clin Cancer Res. 2015 Sep 15;21(18):4062-72. doi: 10.1158/1078-0432.CCR-15-0428. Epub 2015 Jun 9.
PMID: 26059190
 
Nabors LB, Portnow J, Ammirati M, Baehring J, Brem H, Brown P, Butowski N, Chamberlain MC, Fenstermaker RA, Friedman A, Gilbert MR, Hattangadi-Gluth J, Holdhoff M, Junck L, Kaley T, Lawson R, Loeffler JS, Lovely MP, Moots PL, Mrugala MM, Newton HB, Parney I, Raizer JJ, Recht L, Shonka N, Shrieve DC, Sills AK Jr, Swinnen LJ, Tran D, Tran N, Vrionis FD, Weiss S, Wen PY, McMillian N, Engh AM.
J Natl Compr Canc Netw. 2015 Oct;13(10):1191-202.
PMID: 26483059
 
Muñoz C, Juarez G, Muñoz ML, Portnow J, Fineman I, Badie B, Mamelak A, Ferrell B.
Soc Work Health Care. 2008;47(4):455-78. doi: 10.1080/00981380802232396.
PMID: 4.19042496
 
Nabors LB, Portnow J, Ammirati M, Brem H, Brown P, Butowski N, Chamberlain MC, DeAngelis LM, Fenstermaker RA, Friedman A, Gilbert MR, Hattangadi-Gluth J, Hesser D, Holdhoff M, Junck L, Lawson R, Loeffler JS, Moots PL, Mrugala MM, Newton HB, Raizer JJ, Recht L, Shonka N, Shrieve DC, Sills AK Jr, Swinnen LJ, Tran D, Tran N, Vrionis FD, Wen PY, McMillian NR, Ho M.
J Natl Compr Canc Netw. 2014 Nov;12(11):1517-23.
PMID: 25361798
 
Nabors LB, Ammirati M, Bierman PJ, Brem H, Butowski N, Chamberlain MC, DeAngelis LM, Fenstermaker RA, Friedman A, Gilbert MR, Hesser D, Holdhoff M, Junck L, Lawson R, Loeffler JS, Maor MH, Moots PL, Morrison T, Mrugala MM, Newton HB, Portnow J, Raizer JJ, Recht L, Shrieve DC, Sills AK Jr, Tran D, Tran N, Vrionis FD, Wen PY, McMillian N, Ho M; National Comprehensive Cancer Network.
J Natl Compr Canc Netw. 2013 Sep 1;11(9):1114-51.
PMID: 24029126
 
Brown CE, Alizadeh D, Starr R, Weng L, Wagner JR, Naranjo A, Ostberg JR, Blanchard MS, Kilpatrick J, Simpson J, Kurien A, Priceman SJ, Wang X, Harshbarger TL, D'Apuzzo M, Ressler JA, Jensen MC, Barish ME, Chen M, Portnow J, Forman SJ, Badie B.
N Engl J Med. 2016 Dec 29;375(26):2561-9. doi: 10.1056/NEJMoa1610497.
PMID: 28029927
 
Portnow J, Suleman S, Grossman SA, Eller S, Carson K.
Neuro Oncol. 2002 Jan;4(1):22-5.
PMID: 11772429
 
Blakeley J, Portnow J.
Expert Opin Drug Metab Toxicol. 2010 Dec;6(12):1477-91. doi: 10.1517/17425255.2010.523420. Epub 2010 Oct 23. Review.
PMID: 20969450
 
  • 2000 - Present Member, Society for Neuro-Oncology
  • 1999 - Present Member, American Society of Clinical Oncology
  • 1991 - 1992 President, Women in Medicine Taskforce, University of Rochester, American Medical Student Association
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