Leong-Lucille

Lucille A Leong, M.D.

  • Clinical Professor, Department of Medical Oncology & Therapeutics Research
  • Director of Clinical Affairs
  • Coordinator, Medical Oncology Hematology Fellowship Program
  • Medical Oncologist

Lucille A Leong, M.D.

Clinical Specialties
  • Medical Oncology
  • Hematology
Areas of Expertise
  • Gastrointestinal Cancers
Other Languages Spoken
  • Spanish
“I am alive because of this wonderful lady.” - Patient
 
Named repeatedly one of the Best Doctors in America, Lucille Leong, M.D., has been a key member of the City of Hope team for 30 years. In addition to her clinical and research commitments, Dr. Leong directs our Hematology/Oncology Fellowship Program.
 
A Yale graduate, Dr. Leong received her medical degree from Stanford University, then completed her internship and residency at Harbor-UCLA Medical Center in Torrance.
 
An outspoken advocate of diversity in medicine and eliminating inequalities in cancer outcomes, Dr. Leong serves on the advisory board of City of Hope's Center of Community Alliance for Research and Education (CCARE).
  • 2003-present Clinical Professor, Department Medical Oncology & Therapeutics Research, City of Hope, Duarte, CA
  • 2009-2011, Medical Staff President, City of Hope, Duarte, CA
  • 2004-2006, Acting Chair, Department of Medical Oncology & Therapeutics Research, City of Hope, Duarte, CA
  • 1994-present Associate Director for Clinical Affairs, Department of Medical Oncology & Therapeutics Research, City of Hope, Duarte, CA
  • 1987-present, Coordinator of ACGME-accredited Hematology/Medical Oncology
  • Fellowship Program at the City of Hope
  • 1985-2003, Staff Physician, Department of Medical Oncology & Therapeutics Research, City of Hope, Duarte, CA.
  • 1997-present, Assistant Clinical Professor of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA
  • 1986-1997, Clinical Instructor, UCLA School of Medicine, Los Angeles, CA

Locations

Duarte

1500 East Duarte Road, Duarte, CA, 91010

Get Directions

Phone :  626-256-4673

Degrees

  • 1975 -1979, Stanford University School of Medicine, Stanford CA, M.D.
  • 1972 -1975, Yale University, New Haven, CT, B.S. (cum laude)

Fellowship

  • 1983 -1985, City of Hope, Duarte, CA. Fellowship, Medical Oncology, Department of Medical Oncology and Therapeutics Research
  • 1982 -1983, Harbor-UCLA Medical Center. Torrance, CA. Fellowship, Hematology, Division of Hematology

Residency

  • 1979 -1982, Harbor-UCLA Medical Center, Torrance, CA.Internship and Residency, Department of Internal Medicine

Internship

  • 1979 -1982, Harbor-UCLA Medical Center, Torrance, CA.Internship and Residency, Department of Internal Medicine
  • 1993 - present, Licensed Physician Assistant Supervisor
  • 1985, Board certified in subspecialty of Medical Oncology
  • 1984, Board certified in subspecialty of Hematology
  • 1982 - present, Board certified in specialty of Internal Medicine, American Board of Internal Medicine
  • 1980 - present, Licensed Physician of the State of California

Shibata, S., Chow, W., Frankel, P., Juhasz, A., Koczywas, M., Leong, L., Lim, D., Margolin, K., McNamara, M., Morgan, R., Newman, E., Somlo, G., Twardowski, P., Yen, Y., Synold, T., and Doroshow, J.  A Phase I study of oxaliplatin in combination with gemcitabine: Correlation of clinical outcome with gene expression.  Cancer Chemother Pharmcol 59(4): 549-57, 2007.

Morgan, R.J., Jr., Synold, T.W., Gandara, D., Muggia, F., Scudder, S., Reed, E., Margolin, K., Raschko, J., Leong, L., Shibata, S., Tetef, M., Vasilev, S., McGonigle, K., Longmate, J., Yen, Y., Chow, W., Somlo, G., Carroll, M. and Doroshow, J.H.  Phase II trial of carboplatin and infusional cyclosporine with alpha-interferon in recurrent ovarian cancer: A California Cancer Consortium Trial.  Int'l. J Gynecol Cancer 2: 373-8, 2007.

Leong, L.  Challenges and Rewards of Being a Medical Oncologist in Inside the Minds - The Art and Science of Oncology, Aspatore Books: 45-54, 2007.; Lowe, T., Ferrell, B., Leong, L.  Quality-of-Life Issues in the Management of Epithelial Ovarian Cancer.  Curr Treat Options Oncol 8:402-416, 2007.

Yen, Y., Lim, D.W., Chung, V., Morgan, R.J., Leong, L.A., Shibata, S.I., Wagman, S.D., Marx, H., Chu, P.G., Longmate, J.A., Lenz, H-J., Ramanathan, R.K., Belani, C.P., Gandara, D.R.  Phase II study of oxaliplatin in patients with unresectable, metastatic, or recurrent hepatocellular cancer: a California Cancer Consortium Trial. Am J Clin Oncol. 2008 Aug;31(4):317-22 Erratum in: Am J Clin Oncol. 2009 Feb;32(1):98. Wagman, Stephen D [corrected to Wagman, Lawrence D]. PMID: 18845988.

Luu, TH, Morgan, R., Leong, L., Lim., D., McNamara, M., Portnow, J., Frankel, P., Smith, DD, Doroshow, JH, Wong, C., Aparicio, A., Gandara, DR, Somlo, G. A Phase II Trial of Vorinostat (Suberoylanilide Hydroxamic Acid) in Metastatic Breast Cancer: A California Cancer Consortium study. Clin Cancer Res. 2008 Nov 1; 14(21):7138-42. (Erratum in: Clin Cancer Res. 2009 Jan 1; 15(1):416.) PMID: 18981013

Shibata SI, Doroshow JH, Frankel P, Synold TW, Yen Y, Gandara DR, Lenz HJ, a. Chow WA, Leong LA, Lim D, Margolin KA, Morgan RJ, Somlo G, Newman EM. Phase I, b. trial of GTI-2040, oxaliplatin, and capecitabine in the treatment of advanced. c. metastatic solid tumors: a California Cancer Consortium Study. Cancer Chemother. d. Pharmacol. 2009 Nov;64(6):1149-55. PMCID: PMC3046108

Lashkari, A., Chow, W., Valdes, F., Leong, L., Phan, V., Twardowski, P., Kapoor, N., Molina, A., Al-Kadhimi, S., Frankel P., and Somlo, G. Tandem High-dose Chemotherapy Followed by Autologous Transplantation in Patients with Locally Advanced or Metastatic Sarcoma. Anticancer Res. 29: 3281-3288, 2009. PMID: 19661346

Vanderwalde, AM, Howard, M., Leong, L. Liver Abscess as a Complication of Hepatic Transarterial Chemoembolization: A Case Report, Literature Review, and Clinical Recommendations. Gastrointest Cancer Res. 3(6): 247-251, 2009. PMCID: PMC3000072

Senthil, M., Mailey, B., Leong, L., Chung, V., Yen, Y., Chen, Y., Marx, H., Kim, J. Liver-Directed Regional Therapy in the Multi-Disciplinary Management of Hepatocellular Cancer. Curr Cancer Ther Rev. 6(1): 19-25, 2010.

Leong, L., Ninnis, J., Slatkin, N., Rhiner, M., Schroeder, B.P., Morgan, R. Evaluating the Impact of Pain Management (PM) Education on Physician Practice Patterns - A Continuing Medical Education (CME) Outcomes Study. J Canc Educ. 25:224-228, 2010. PMID: 20204577

Morgan, R., Synold, T., Mamelak, A., Lim, D., Al-Kadhimi, Z., Twardowski, P., Leong, L., Chow, W., Margolin, K., Shibata, S., Somlo, G., Yen, Y., Frankel, P., Doroshow, J.  Plasma and Cerebrospinal Fluid Pharmacokinetics of Topotecan in Phase I Trial of Topotecan, Tamoxifen and Carboplatin, in the Treatment of Recurrent or Refractory Brain or Spinal Cord Tumors. Cancer Chemother Pharmacol. 66(5): 927-33, 2010. PMID: 20107803

Morgan, R.J., Jr., Leong, L., Chow, W., Gandara, D., Frankel, P., Garcia, A., Lenz, H-J., Doroshow, J.H. Phase II Trial of Bryostatin-1 in Combination with Cisplatin in Patients with Recurrent or Persistent Epithelial Ovarian Cancer: A California Cancer Consortium Study. Investigational New Drugs. 2010 Oct 9. [Epub ahead of print]. PMID: 20936324

Engstrom PF, Arnoletti JP, Benson AB 3rd, Berlin JD, Berry JM, Chen YJ, Choti MA, Cooper HS, Dilawari RA, Early DS, Enzinger PC, Fakih MG, Fleshman J Jr, Fuchs C, Grem JL, Knol JA, Leong LA, Lin E, Mulcahy MF, Rohren E, Ryan DP, Saltz L, Shibata D, Skibber JM, Small W, Sofocleous C, Thomas J, Venook AP, Willett C.  NCCN.  NCCN clinical practice guidelines in oncology. Anal carcinoma.  J Natl Compr Canc Netw.  Jan;8(1):106-20, 2010. PMID: 20064293

Krishnan, A., Reckamp, K., Leong, L. Training Program in Blood Diseases: City of Hope Cancer Center Hematology-Oncology Fellowship and Hematopoietic Stem Cell Transplantation (HSCT) Fellowship. Amer. Jour Hem. 86(2): 197-198, 2011. PMID: 21264906

Benson AB 3rd, Arnoletti JP, Bekaii-Saab T, Chan E, Chen YJ, Choti MA, Cooper HS,  Dilawari RA, Engstrom PF, Enzinger PC, Fleshman JW Jr, Fuchs CS, Grem JL, Knol JA, Leong LA, Lin E, May KS, Mulcahy MF, Murphy K, Rohren E, Ryan DP, Saltz L, Sharma S, Shibata D, Skibber JM, Small W Jr, Sofocleous CT, Venook AP, Willett C.  Colon Cancer.  J Natl Compr Canc Netw. Nov 1;9 (11):1238-90, 2011. PMID: 22056656

Somlo G, Martel CL, Lau SK, Frankel P, Ruel C, Gu L, Hurria A, Chung C, Luu T, Morgan R Jr, Leong L, Koczywas M, McNamara M, Russell CA, Kane SE. A phase I/II prospective, single arm trial of gefitinib, trastuzumab, and docetaxel in patients with stage IV HER-2 positive metastatic breast cancer.  Breast Cancer Res Treat. Nov 1., 2011 PMID: 22042372

Portnow, J., Frankel, P., Koehler, S., Twardowski, P., Shibata, S., Martel, C., Morgan, R., Cristea, M., Chow, W., Lim, D., Chung, V., Reckamp, K., Leong, L., Synold, T. A phase I study of bortezomib and temozolomide in patients with advanced solid tumors. Cancer Chemother Pharmacol. Aug 18, 2011.  PMID: 21850464

Portnow J, Frankel P, Koehler S, Twardowski P, Shibata S, Martel C, Morgan R, Cristea M, Chow W, Lim D, Chung V, Reckamp K, Leong L, Synold TW.  A phase I study of bortezomib and temozolomide in patients with advanced solid tumors.  Cancer Chemother Pharmacol. 2012 Feb;69(2):505-14. PMID: 21850464

Somlo G, Martel CL, Lau SK, Frankel P, Ruel C, Gu L, Hurria A, Chung C, Luu T, Morgan R Jr, Leong L, Koczywas M, McNamara M, Russell CA, Kane SE.  A phase I/II prospective, single arm trial of gefitinib, trastuzumab, and docetaxel in patients with stage IV HER-2 positive metastatic breast cancer.  Breast Cancer Res Treat. 2012 Feb;131(3):899-906. PMID: 22042372

Morgan RJ Jr, Leong L, Chow W, Gandara D, Frankel P, Garcia A, Lenz HJ, Doroshow JH.  Phase II trial of bryostatin-1 in combination with cisplatin in patients with recurrent or persistent epithelial ovarian cancer: a California cancer consortium study.  Invest New Drugs. 2012 Apr;30(2):723-8. PMID: 20936324

Benson AB 3rd, Arnoletti JP, Bekaii-Saab T, Chan E, Chen YJ, Choti MA, Cooper HS, Dilawari RA, Engstrom PF, Enzinger PC, Fakih MG, Fleshman JW Jr, Fuchs CS, Grem JL, Leong LA, Lin E, May KS, Mulcahy MF, Murphy K, Rohren E, Ryan DP, Saltz L, Sharma S, Shibata D, Skibber JM, Small W Jr, Sofocleous CT, Venook AP, Willett C, Freedman-Cass DA. Anal Carcinoma, Version 2.2012: featured updates to the NCCN guidelines. National Comprehensive Cancer Network. J Natl Compr Canc Netw. 2012 Apr;10(4):449-54. PMID: 22491045

Uemura M, Morgan R, Jr, Mendelsohn M, Kagan J, Saavedra C, Leong L.  Enhancing quality improvements in cancer care through CME activities at a nationally recognized cancer center.  Submission to Journal of Continuing Education in the Health Professions, July, 2012.

VanderWalde A, Ye W, Frankel P, Asuncion D, Leong L, Luu T, Morgan R,  Twardowski P, Koczywas M, Pezner R, Paz IB, Margolin K, Wong J, Doroshow JH, Forman S, Shibata S, Somlo G.  Long-term survival after high-dose chemotherapy followed by peripheral stem cell rescue for high-risk, locally advanced/ inflammatory, and metastatic breast cancer.  Biol Blood Marrow Transplant. 2012 Aug;18(8):1273-80. PMID: 22306735

Leong L.  Clinical Relevance of Targeting Cancer Metastases. In Metastatic Cancer: Integrated Organ System and Biological Approach. Jandial R. and Hunt K., ed.  Landes Bioscience: 2012: 1-11. (Posted on Madame Cuie Bioscience Database May 18, 2012.  Book publication date October 29. 2012.)

  • 2007 American Society of Clinical Oncology
  • 2001 American Association for Cancer Education
  • 2004 National Comprehensive Cancer Network
  • 2005 National Cancer Institute
  • 2009 Association of American Medical Colleges
  • 1998 SWOG (Southwest Oncology Group) National Cooperative Clinical Trials Group for Cancer Treatment
  • 1996 NSABP (National Surgical Adjuvant Breast Project)
  • 2007 GOG (Gynecologic Oncology Group)
  • 2001 LACMA/California Medical Association
  • 2007-2008 Los Angeles County Basin Clinical and Translational Science Institute
  • 1997 Harbor-UCLA Professional Staff Association
  • 1993 American Cancer Society
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