Bart Roep

Bart O. Roep, Ph.D.

  • Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes
  • Professor and Founding Chair, Department of Diabetes Immunology

Bart O. Roep, Ph.D.

Research Focus :
  • Type 1 diabetes
  • Immunology
  • Immunotherapy
  • Gene therapy

Bart O. Roep, Ph.D., is Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes and the founding chair of the Department of Diabetes Immunology within City of Hope's Diabetes & Metabolism Research Institute. He is an internationally recognized authority and key opinion leader on multiple aspects of type 1 diabetes, with particular interest in understanding the cause of the disease and translating this knowledge into immune intervention strategies (including gene therapy, stem cell therapy and bone marrow transportation) with the ultimate goal to cure type 1 diabetes.

Dr. Roep’s mission is to cure people from type 1 diabetes. His quest of over 25 years has been honored with multiple scientific and medical awards, including the most prestigious national and European awards in diabetes such as the Minkowski Prize for outstanding contributions to the advancement of knowledge in the field of diabetes mellitus.

Highlights of Dr. Roeps' career include discovering which targets in insulin-producing beta-cells are recognized by self-destructive T cells, which can be translated into immune-based therapies targeting this mechanism. He is also the first to discover immune system factors that predicts clinical outcome of islet transplantation for type 1 diabetic islet recipients, setting the stage for personalized medicine.

Dr. Roep received his medical and doctorate degrees at Leiden University in the Netherlands and his Master of Science degree at the University of Amsterdam.

  • 2015 to present - Professor and Chair, Department of Diabetes Immunology, Diabetes & Metabolism Research Institute at City of Hope, Duarte, CA
  • 2015 to present - Visiting Professor, Danish Diabetes Academy, Odense, Denmark
  • 2015 to present - Adjunct Director, Bartholin Institute, University of Copenhagen, Copenhagen, Denmark
  • 2009 to present - Professor of Medicine, Strategic Professor of Diabetology, Immunopathology & Intervention, Leiden University, Leiden, Netherlands
  • 2008 to present - Director, National Diabetes Expert Center on Immunoprotection
  • 2001 to present - Head, Division of Autoimmunity, Leiden University, Leiden, Netherlands
  • 1993 to present - Principal Investigator, Diabetes Research, Leiden University
  • 2001 to 2009 - Associate Professor of Medicine, Immunology of Diabetes, Leiden University, Leiden, Netherlands
  • 1998 to 2001 - Assistant Professor and Clinical Research Fellow, Immunology of Diabetes, Leiden University, Leiden, Netherlands


  • 1991 - M.D., Ph.D., Leiden University, Leiden, Netherlands 1987 - M.S., University of Amsterdam, Netherlands


  • 1993 to 1998 - Fellow of the Royal Academy of Arts and Sciences, Netherlands
  • 1992 to 1993 - Postdoctoral Fellow, Department of Immunohaematology & Blood Bank, Leiden University Medical Center, Leiden, Netherlands
  • 1991 to 1992 - Senior Research Fellow, Hormone Research Institute, University of California, San Francisco
  • 2015 - Elected Member of the Danish Diabetes Academy
  • 2014 - Gerold & Kayla Grodsky Award
  • 2013 - JDRF Netherlands Award for T1D Scientific Excellence
  • 2011 - Corona-Gallina Prize for Scientific Excellence
  • 2010 - Dutch Diabetes Patient Society Award
  • 2010, 2013, 2014 - Presidential Lecture, EASD-AIDPIT Society
  • 2008 to 2009 - Best Teaching Professor in English Course, Faculty of Medicine
  • 2009 - Tammeling Award Nomination by Medical Students
  • 2007 - Vici Award
  • 2007 - Mary Jane Kugel Research Award, JDRF
  • 2002 - Minkowski Prize
  • 2001 - Bronze Hummingbird, Diabetes Patient Society
  • 2001 - Honorary Lecture, Japan Diabetes Society
  • 1999 - Marie Parijs Prize for Innovative Clinical Research
  • 1993 - Royal Academy of Arts and Sciences Fellow
  • 1990 to 1991 - Eli Lilly Diabetes Award
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