An NCI-designated Comprehensive Cancer Center

Mark Wakabayashi, M.D., M.P.H.

Gynecologic Oncology Surgeon
Clinical Expertise
  • Cytoreductive/debulking cancer surgery
  • Gynecologic Oncology
  • Heated Intraperitoneal Chemotherapy (HIPEC)
Research Focus
  • Gynecologic Oncology
Appointments
Chief, Division of Gynecologic Oncology, Department of Surgery; Co-director, Gynecological Oncology/Peritoneal Malignancy Program; Associate Clinical Professor, Department of Surgery
Contact
Referring Physicians/Colleagues: 626-218-5001
Email: [email protected]

Clinical Teams

  • Gynecologic Oncology and Peritoneal Malignancy Program
  • Cervical Cancer
  • Uterine and Endometrial Cancers
Mark Wakabayashi, M.D., is an accomplished surgeon who focuses on treating ovarian, cervical, endometrial and other gynecological cancers. As chief of the gynecologic oncology division at City of Hope’s department of surgery, Dr. Wakabayashi and his team are experts in minimally invasive and robotically-assisted surgeries, which can be as effective as traditional surgery but with reduced scarring, pain and recovery time.
 
Dr. Wakabayashi is also an expert in cytoreductive/debulking cancer surgery, which can significantly improve outcomes for patients by enhancing radiation and chemotherapy effectiveness.
 
Dr. Wakabayashi earned his medical degree at the Stritch School of Medicine, Loyola University of Chicago and a Master of Public Health from University of Hawaii at Manoa. Prior to City of Hope, Dr. Wakabayashi has practiced at John A. Burns School of Medicine at the University of Hawaii, Women’s Cancer Center at Kapiolani Women’s and Children’s Medical Center and Kaiser Permanente Medical Center at Moanalua.

Locations

City of Hope Comprehensive Cancer Center, 1500 East Duarte Road

Duarte, CA 91010

Peer-reviewed

1.    Chung CP, Sargent RE, Chung NT, Lacey JV Jr., Wakabayashi MT. Graft-Versus-Host Disease-Associated Vulvovaginal Symptoms after Bone Marrow Transplantation. Biol Blood Marrow Transplant 2015 Sep

2.    Cohn DE, Havrilesky LJ, Osann K, Lipscomb J, Hsieh S, Walker JL, Wright AA, Alvarez RD, Karlan BY, Bristow RE, DiSilvestro PA, Wakabayashi MT, Morgan R, Mukamel DB, Wenzel L. Consensus in controversy: The modified Delphi method applied to Gynecologic Oncology practice. Gynecol Oncol. 2015 Sep;138(3):712-6

3.    Wen W, Liang W, Wu J, Kowolik CM, Buettner R, Scuto A, Hsieh MY, Hong H, Brown CE, Forman SJ, Horne D, Morgan R, Wakabayashi M, Dellinger TH, Han ES, Yim JH,  Jove R. Targeting JAK1/STAT3 signaling suppresses tumor progression and metastases in a peritoneal model of human ovarian cancer. Mol Cancer Ther. 2014 Dec;13(12):3037-48, 2014  

4.    Denlinger CS, Ligibel JA, Are M, Baker KS, Demark-Wahnefried W, Dizon D, Friedman DL, Goldman M, Jones L, King A, Ku GH, Kvale E, Langbaum TS, Leonardi-Warren K, McCabe MS, Melisko M, Montoya JG, Mooney K, Morgan MA, Moslehi JJ, O'Connor T, Overholser L, Paskett ED, Peppercorn J, Raza M, Rodriguez MA, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian NR, Freedman-Cass DA. Survivorship: screening for cancer and treatment effects, version 2.2014. J Natl Compr Canc Netw. 2014 Nov;12(11):1526-31

5.    Denlinger CS, Ligibel JA, Are M, Baker KS, Demark-Wahnefried W, Dizon D, Friedman DL, Goldman M, Jones L, King A, Ku GH, Kvale E, Langbaum TS, Leonardi-Warren K, McCabe MS, Melisko M, Montoya JG, Mooney K, Morgan MA, Moslehi JJ, O'Connor T, Overholser L, Paskett ED, Peppercorn J, Raza M, Rodriguez MA, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian NR, Freedman-Cass DA. Survivorship: nutrition and weight management, Version 2.2014. Clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2014 Oct;12(10):1396-406.

6.    Denlinger CS, Ligibel JA, Are M, Baker KS, Demark-Wahnefried W, Dizon D, Friedman DL, Goldman M, Jones L, King A, Ku GH, Kvale E, Langbaum TS, Leonardi-Warren K, McCabe MS, Melisko M, Montoya JG, Mooney K, Morgan MA, Moslehi JJ, O'Connor T, Overholser L, Paskett ED, Peppercorn J, Raza M, Rodriguez MA, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian NR, Freedman-Cass DA. Survivorship: Healthy lifestyles, Version 2.2014. Clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2014 Oct;12(10):1222-37

7.    Denlinger CS, Ligibel JA, Are M, Baker KS, Demark-Wahnefried W, Dizon D, Friedman DL, Goldman M, Jones L, King A, Ku GH, Kvale E, Langbaum TS, Leonardi-Warren K, McCabe MS, Melisko M, Montoya JG, Mooney K, Morgan MA, Moslehi JJ, O'Connor T, Overholser L, Paskett ED, Peppercorn J, Raza M, Rodriguez MA, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian NR, Freedman-Cass DA. Survivorship: Immunizations and prevention of infections. Version 2.2014. J Natl Compr Canc Netw. 2014 Aug;12(8):1098-111

8.    Denlinger CS, Ligibel JA, Are M, Baker KS, Demark-Wahnefried W, Friedman DL, Goldman M, Jones L, King A, Ku GH, Kvale E, Langbaum TS, Leonardi-Warren K, McCabe MS, Melisko M, Montoya JG, Mooney K, Morgan MA, Moslehi JJ, O'Connor T, Overholser L, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian NR, Freedman-Cass DA. Survivorship: Cognitive function, vesrsion 1.2014. J Natl Compr Canc Netw. 2014 Jul; 12(7):976-86

9.    Denlinger CS, Ligibel JA, Are M, Baker KS, Demark-Wahnefried W, Friedman DL, Goldman M, Jones L, King A, Ku GH, Kvale E, Langbaum TS, Leonardi-Warren K, McCabe MS, Melisko M, Montoya JG, Mooney K, Morgan MA, Moslehi JJ, O'Connor T, Overholser L, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D. Survivorship: fatigue, version 1.2014 J Natl Compr Canc Netw. 2014 Jun;12(6):876-87.

10.    Denlinger CS, Ligibel JA, Are M, Baker KS, Demark-Wahnefried W, Friedman DL, Goldman M, Jones L, King A, Ku GH, Kvale E, Langbaum TS, Leonardi-Warren K, McCabe MS, Melisko M, Montoya JG, Mooney K, Morgan MA, Moslehi JJ, O'Connor T, Overholser L, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D. Survivorship: sleep disorders, version 1.2014. J Natl Compr Canc Netw. 2014 May;12(5):630-42

11.    Denlinger CS, Ligibel JA, Are M, Baker KS, Demark-Wahnefried W, Friedman DL, Goldman M, Jones L, King A, Ku GH, Kvale E, Langbaum TS, Leonardi-Warren K, McCabe MS, Melisko M, Montoya JG, Mooney K, Morgan MA, Moslehi JJ, O'Connor T, Overholser L, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D. Survivorship: pain, 1.2014. J Natl Compr Canc Netw. 2014 Apr;12(4):488-500

12.    Denlinger CS, Carlson RW, Are M, Baker KS, Davis E, Edge SB, Friedman DL, Goldman M, Jones L, King A, Kvale E, Langbaum TS, Ligibel JA, McCabe MS, McVary KT, Melisko M, Montoya JG, Mooney K, Morgan MA, O'Connor T, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D. Survivorship: sexual dysfunction (male), version 1.2013. J Natl Compr Canc Netw. 2014 Mar 1;12(3):356-63

13.    Denlinger CS, Carlson RW, Are M, Baker KS, Davis E, Edge SB, Friedman DL, Goldman M, Jones L, King A, Kvale E, Langbaum TS, Ligibel JA, McCabe MS, McVary KT, Melisko M, Montoya JG, Mooney K, Morgan MA, O'Connor T, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D. Survivorship: sexual dysfunction (female), version 1.2013. J Natl Compr Canc Netw. 2014 Feb;12(2):184-92

14.    Denlinger CS, Carlson RW, Are M, Baker KS, Davis E, Edge SB, Friedman DL, Goldman M, Jones L, King A, Kvale E, Langbaum TS, Ligibel JA, McCabe MS, McVary KT, Melisko M, Montoya JG, Mooney K, Morgan MA, O'Connor T, Paskett ED, Raza M, Syrjala KL, Urba SG, Wakabayashi MT, Zee P, McMillian N, Freedman-Cass D.Survivorship: introduction and definition. Clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2014 Jan;12(1):34-45

15.    Cohn DE, Leitao M, Levenback C, Berkowitz R, Roman L, Lucci J, Kim S, Lancaster J, Odunsi K, Wakabayashi M, Goff BA. Reporting of quality measures in gynecologic oncology programs at Prospective Payment System (PPS)-Exempt Cancer Hospitals: an early glimpse into a challenging initiative. Gynecol Oncol. 2013 Sep; 130(3):403-6

16.    Han ES, MD. PhD, Wakabayashi M, MD Leong L, Angiogenesis Inhibitors in the Treatment of Epithelial Ovarian Cancer. Curr Treat Options Oncol. 2013 Mar; 14(1):22-33

17.    Yang C, Lee H, Jove V, Deng J, Zhang W, Liu X, Forman S, Dellinger TH, Wakabayashi M, Yu H, Pal S. Prognostic significance of B-cells and pSTAT3 in patients with ovarian cancer. PLOS One.  2013  Jan;8(1)

18.    Otis-Green, S. Wakabayashi MT, Morgan, R., Hakim, A., Ferrell, B., Sun, V.; Yang, E., Grant, M., J. Palliative care opportunities for women with advanced ovarian cancer associated with intraperitoneal chemotherapy. J Palliative Med. 2013 Jan; 16(1): 44-53

19.    Sun, V; Otis-Green, S.; Morgan, R. Wakabayashi, M; Hakim, A.; Callado, M.E.; Yang, E.; Ferrell, B.; Grant, M.  Toxicities, complications, and clinical encounters during intraperitoneal chemotherapy in 17 women with ovarian cancer. European Journal of Oncology Nursing. 2012 Nov; 17 (2013): 375-380

20.    Ojo J, De Silva S, Han E, Lin P, Wakabayashi M, Nelson, Lai L.  Krukenberg Tumors from colorectal cancer: Presentation, Treatment, and Outcome.  Am Surg. 2011 Oct; 77(10): 1381-1385

21.    Han ES and Wakabayashi MT, Indications for Minimally Invasive Surgery for Ovarian Cancer. J Natl Compr Canc Netw. 2011 Jan; 9(1): 126-132

22.    McKenzie S, Baek JH, Wakabayashi M, Garcia-Aguilar J, Pigazzi A: Totally laparoscopic right colostomy with transvaginal specimen extraction: the authors’ initial institutional experience. Surg Endosc. 2010 Aug; 24(8):2048-52

23.    Ashing-Giwa KT, Gonzalez P, Lim JW, Chung C, Paz B, Somlo G, Wakabayashi MT: Diagnostic and therapeutic delays among a multiethnic sample of breast and cervical cancer survivors, Cancer. 2010 Jul; 1:116(13):3195-204

24.    Han ES, Lin P, Wakabayashi, MT.: Current status on biologic therapies in the treatment of epithelial ovarian cancer; Curr Treat Options Oncol. 2009 Apr; 10(1-2):54-66

25.    Lin PS, Wakabayashi MT, Han ES, Role of robotic surgery in endometrial cancer. Curr Treat Options Oncol. 2009 Apr; 10(1-2): 33-43.

26.    Wakabayashi MT, Lin PS, Hakim AA, The role of cytoreductive/debulking surgery in ovarian cancer. J Natl Compr Canc Netw. 2008 Sept; 6(8):803-811

27.    Hakim AA, Lin PS, Wilczynski S, Nguyen K, Lynes B, Wakabayashi MT: Indications and efficacy of the human papillomavirus vaccine.  Curr Treat Options Oncol. 2007 Dec; 8(6):393-401

28.    Hernandez BY, McDuffie K, Zhu X, Wilkens LR, Killeen J, Kessel B, Wakabayashi MT, Bertram CC, Easa D, Ning L, Boyd J, Sunoo C, Kamemoto L, Goodman MT: Anal human papillomavirus infection in women and its relationship with cervical infection. Cancer Epidemiol Biomarkers Prev. 2005 Nov; 14(11):2550-2556

29.    Oyama, IA, Wakabayashi MT, Frattarelli LC, Kessel B: Local anesthetic reduces the pain of colposcopic biopsies: A randomized trial. Am J Obstet Gynecol. 2003 May; 188:1164-5

30.    Wakabayashi MT, Da Silva DM, Potkul RK and Kast WM: Comparison of human papillomavirus type 16 L1 chimeric virus-like particles versus L1/L2 chimeric virus-like particles in tumor prevention. 2002 Intervirology 45:300-307

31.    Wakabayashi MT, Tretiak M, Kessel B, Kosasa T, Aeby T, Kamemoto L and Sharma S: Intravaginal misoprostol for medical evacuation of first trimester Missed abortion. Clin J Women’s Health. 2001; 1:80-85

32.    Da Silva DM, Eiben GL, Fausch SC, Wakabayashi MT, Rudolf MP Velders MP, and Kast WM: Cervical cancer vaccines: emerging concepts and developments.  J Cell Physiol. 2001 Feb; 186:169-182

33.    Wakabayashi MT: Laparoscopic assisted vaginal hysterectomy/ laparoscopic hysterectomy.  Hi Med J. 1991 Jan; 58:12-14
 

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