Anti-PD-L1 checkpoint inhibitors: Decoding the mystery

July 24, 2019 | City of Hope

An study conducted by Michael Caligiuri, M.D., and Jianhua Yu, Ph.D., unveiled why anti-PD-L1 monoclonal antibodies (mAb) are still effective in fighting tumors that lack PD-L1 receptors on their cells.

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City of Hope enrolling patients in clinical trial for HPV-linked cancers

August 20, 2019 | Letisia Marquez

A first-in-human, phase 1 T cell trial for patients who have human papillomavirus (HPV)-associated cancers that have relapsed, or are resistant to treatment, is now open at City of Hope. The institution is the first to open such a trial on the West Coast.

First in the nation: City of Hope to offer experimental T cell drug for liver cancer patients

August 5, 2019 | Zen Vuong

An ongoing clinical study in China on the drug showed liver tumor shrinkage, regression of metastatic tumors and fewer side effects than in other T cell clinical trials.

Leukemia patient finds donor halfway around the world

May 9, 2019 | Letisia Marquez

Acute myeloid leukemia patient Leif Voeltz's perfect match for a bone marrow transplant was located in Germany. Now Marcel Waldmann is traveling to the U.S. for the first time to meet the man whose life he saved.

Def Leppard guitarist defies cancer diagnosis

March 29, 2019 | Samantha Bonar

Def Leppard guitarist Vivian Campbell was diagnosed with Hodgkin's lymphoma in 2013. After chemotherapy and a stem cell transplant failed, immunotherapy has kept his cancer at bay for the last four years.