Cancer From Cradle To Grave: Age And Its Effects On Cancer Biology, Therapy and Outcomes
The 29th Beckman Symposium
November 1, 2019

8 to 8:30 a.m.
Registration and Breakfast

8:30 to 8:40 a.m. 

Steven Rosen, M.D.
Provost and Chief Scientific Officer
Director, Comprehensive Cancer Center and 
Beckman Research Institute
Irell & Manella Cancer Center Director's Distinguished Chair 
SPOC (Strategic Portfolio Optimization Committee) Co-Chairman
8:40 to 8:45 a.m. 
Overview of Morning Session: How aging biology informs cancer

Mark LaBarge, Ph.D.
Professor, Department of Population Sciences, 
Beckman Research Institute at the City of Hope
8:45 to 9:30 a.m.
Aging, Tissue Ecology, and the Evolution of Cancer
James DeGregori, Ph.D. 
Courtenay C. and Lucy Patten Davis Endowed Chair in Lung Cancer Research
Professor, Department of Biochemistry and Molecular Genetics
Deputy Director, University of Colorado Cancer Center
9:30 to 10:15 a.m. 
DNA methylation in stem cell aging

Jean-Pierre Issa, M.D.
President and CEO
Coriell Institute for Medical Research
10:15 to 10:25 a.m.
10:25 a.m. to 11:10 a.m. 
Anticancer mechanisms in long-lived cancer resistant rodents

Vera Gorbunova, Ph.D.
Doris Johns Cherry Professor of Biology
Co-Director Rochester Aging Research Center
Department of Biology
University of Rochester
11:10 a.m. to 12:10 p.m.
12:10 to 12:15 p.m.
Overview of 1st Afternoon Session: How development biology informs cancer
Leo Wang, M.D., Ph.D.
Assistant Professor, Departments of Pediatrics and Immuno-Oncology
Pediatric Hematologist/ Oncologist
City of Hope
12:15 to 1 p.m.
Myelin Plasticity in Health and Disease

Michelle Monje-Deisseroth, M.D., Ph.D.
Associate Professor, Department of Neurology and Neurological Sciences 
Stanford University 
1:00 to 1:45 p.m.
Structure and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Human Cancer

Cigall Kadoch, Ph.D.
Assistant Professor of Pediatric Oncology, Dana-Farber Cancer Institute
Affiliated Faculty, Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Institute Member and Epigenomics Program Co-Director, Broad Institute of MIT and Harvard 
1:45 to 2:30 p.m.
Cloak and Dagger: How Pediatric Brain Tumors Hide from the Immune System

(And What We Can Do About It)
Robert Wechsler-Reya, Ph.D.
Director and Professor
Tumor Initiation and Maintenance Program
Sanford Burnham Prebys Medical Discovery Institute 
2:30 to 3:15 p.m. 
The role of developmental signaling pathways in pediatric malignant germ cell tumors

James Amatruda, M.D., Ph.D.
Sarcoma Research Chair 
Children's Center for Cancer and Blood Diseases
Division of Hematology, Oncology and Blood & Marrow Transplantation
Children's Hospital Los Angeles
Professor of Pediatrics and Medicine 
Keck School of Medicine
University of Southern California

3:15 to 3:25 p.m.
3:25 to 3:30 p.m. 
Overview of 2nd Afternoon Session: Challenges and opportunities in the care of young and old
Saro Armenian, D.O., M.P.H.
Associate Professor, Departments of Pediatrics and Population Sciences
Director, Division of Outcomes Research, Department of Population Sciences
City of Hope
William Dale, M.D., Ph.D. 
Arthur M. Coppola Family Chair in Supportive Care Medicine 
Director of the Center for Cancer and Aging 
Clinical Professor, Department of Supportive Care Medicine
City of Hope
3:30 to 4:15 p.m. 
Premature aging and frail health in childhood cancer survivors

Kristen Ness, PT, Ph.D., FAPTA
Department of Epidemiology and Cancer Control
St Jude Children’s Hospital 
4:15 to 5:00 p.m. 
Symptom Science in Cancer Survivors: Advances in Biology and Management

Patricia Ganz, M.D.
Distinguished Professor of Health Policy & Management and Medicine
UCLA Fielding School of Public Health
Director, Cancer Prevention & Control Research
David Geffen School of Medicine at UCLA
Jonsson Comprehensive Cancer Center
5 to 5:45 p.m.
Treating older adults with cancer: embracing complexity to personalize care

Heidi Klepin, M.D.
Hematology and Oncology

*Schedule time subject to change