David Chen Lab

David Chen, Ph.D. is an assistant professor and the director of the Division of Epigenetic and Transcriptional Engineering in the Department of Systems Biology. Combining patient-derived leukemia and lymphoma xenografts, dCas9-technology for genetic engineering, and computational modeling, Chen and his team will interrogate the genome-wide effects of modifiers that write and erase epigenetic marks and their contribution to malignant leukemia and lymphoma. Chen trained in the group of Scott Armstrong, M.D., Ph.D., at Memorial Sloan Kettering Cancer Center and the Dana-Farber Cancer Institute and is currently a National Institute of Health Pathway to Independence Award (K99/R00) scholar, with a main research emphasis on MLL-rearranged leukemias.