An NCI-designated Comprehensive Cancer Center

Leo Wang Lab

Protein-Focused Stem Cell Research
Our research focuses on using leading-edge mass spectrometric technologies to identify novel activation pathways in small numbers of blood cells. Our innovative mass spectrometry platforms enable us to phosphoproteomically profile hematopoietic stem and progenitor cells, leukemia cells and immune cells as they undergo state and fate transitions.
These strategies, combined with in vitro and in vivo model systems, will enable us to understand and to treat pediatric blood cancers and solid tumors more effectively.

Principal Investigator

Leo David Wang, M.D., Ph.D.
Pediatric Hematologist - Oncologist
Role: Principal Investigator
Research Focus: Hematopoietic Stem and Progenitor Cell Biology
Immune Cell Signaling and Engineering

Principal Investigator

Leo David Wang, M.D., Ph.D.
Pediatric Hematologist - Oncologist
Role:Principal Investigator
Research Focus: Hematopoietic Stem and Progenitor Cell Biology; Immune Cell Signaling and Engineering

Lab Members

Research Associate
Sr. Administrative Assistant
Research Associate
Staff Scientist

Lab Alumni

  • Nathan Hendricks, Ph.D.
  • Sadie Johnson, Ph.D.
  • Antigoni Manousopoulou , M.D., Ph.D.
  • MeiLu McDermott
  • Chris Meeks
  • Shilpa Shahani, M.D.
  • Matthew Yap

Lab Publications

Default publication image
Leo Wang's Publications
To view a complete list of publications, please click the link below.

Research Support

Pediatric cancer research is woefully underfunded; only 4 percent of the budget of the National Cancer Institute is dedicated to this critically important work.

We rely on support from foundations and other philanthropic sources to keep our lab running and to continue our work to find cures for pediatric brain and blood cancers.

We thank all of our wonderful donors for their past, current and future support.


Current Support


Previous Support

In the News


HLA typing — a simple genetic procedure used in bone marrow transplants — might help determine who is most at risk for contracting COVID-19, who might have the worst response and how the most effective vaccine can be developed.

Leo David Wang Bio Photo

The complex process of cell division is being studied at City of Hope by a team of stem cell biologists led by Leo David Wang, M.D., Ph.D.

Leo Wang

Dual-trained pediatric oncologist and scientist Leo Wang, M.D., Ph.D., is working in the lab to understand how blood cells develop and grow, and plans to use that information to help patients with cancer live longer and experience fewer side effects of treatment.


The goal of the Leo Wang Lab is to revolutionize the way that pediatric and blood cancers are treated, and we could not be more thrilled to bring our innovative and exciting scientific research group to the San Gabriel Valley.
We are looking for enthusiastic, self-motivated individuals who thrive in a fast-paced, challenging startup research environment, and who can interact well with others as part of a cohesive team. If you have a desire to make a significant impact in health care, and have the fortitude to work hard, we invite you to contact us.

Lab Location & Contact

Leo Wang Lab
1500 East Duarte Road
Duarte, CA 91010