Human Islet Resource Network Bioinformatics Center

The Human Islet Resource Network (HIRN) is a national team-based program that unites diabetes researchers into consortia exploring important issues relating to insulin-producing beta cells:

  • Consortium on Beta Cell Death and Survival
  • Consortium on Human Islet Biomimetics
  • Consortium on Modeling Autoimmune Interactions
  • Consortium on Targeting and Regeneration
  • Human Pancreas Analysis Program
This collaboration in biomedical science was established in 2014 through a collaboration of funding agencies—the National Institute of Diabetes and Kidney Disease and the Type 1 Diabetes Statutory Funding Program.
City of Hope’s Department of Diabetes & Cancer Discovery Science is the home of the HIRN Bioinformatics Center with John Kaddis, Ph.D., assistant professor, Department of Diabetes & Cancer Discovery Science, leading the center as principal investigator.

Our Role

The HIRN Bioinformatics Center serves as the network’s hub for shared resources and data analysis. With the goal of advancing knowledge about type 1 diabetes, we meet essential technical needs of HIRN investigators:

  • Developing and supporting cloud-based services for handling data, from storage and sharing to analysis and visualization
  • Processing and analyzing data
  • Training scientists to get the most out of our bioinformatics resources
  • Providing expert consultation

Our Impact

HIRN research as of August 2018:

  • 35 grants from the National Institutes of Health
  • More than 100 investigators in five countries
  • 265 publications

For Investigators

HIRN Bioinformatics Center resources