The Fueger Lab

The Fueger Lab works at the intersection of science meant to address diabetes and liver disease. We apply an engineer’s eye to the signaling mechanisms that control metabolism in health — and go awry in disease.
We have a special interest in understanding a particular biochemical signaling pathway that sends orders to divide, die, proliferate or differentiate to cells such as insulin-producing beta cells, affecting metabolism in both the pancreas and the liver. Whereas many studies in diabetes, cancer and metabolism seek to block pathways that contribute to disease when messenger proteins are overexpressed, our investigations may lead to treatments that stimulate pathways that are suppressed.