Key publications

  • In a pair of studies published in the journal Cell Metabolism in 2007, Dr. Huss and colleagues demonstrated the involvement of the nuclear receptors ERRa and ERRg in a host of processes: normal differentiation and growth in skeletal muscle, insulin resistance, muscle injury-regeneration and the pathophysiology of heart disease. These results had a fundamental impact on the direction of research into ERR, from the initial discovery of the role that ERRa and ERRg play in metabolism to the development of genetic and physiologic models to explore new aspects of ERR function.