The Lei Jiang Lab

The Lei Jiang Lab explores metabolism as a coordinated system, both when in balance and when thrown out of balance by disease. In particular, we study changes in how the body processes sugar and amino acids in diabetes and cancer.
Our investigations zero in on mitochondria—the powerhouse within cells themselves. To gain insight into these mechanisms within live cells, we track metabolism with leading-edge imaging techniques using a nonradioactive tracing agent for mass spectrometry.
With an eye toward the evolving world of precision medicine, we also use computational tools to process vast amounts of data and to model biological systems. Our findings have the potential to determine targets for new therapies against cancer and diabetes.