The Thurmond Lab

The Thurmond Lab seeks to identify cellular and molecular mechanisms behind diabetes development and find therapies that can stop or reverse the disease’s progression.
Our science centers on multitaskers, messenger proteins that play a beneficial role across multiple types of tissue. In this case, those proteins both increase the production of insulin — essential to the body’s ability to process sugar — and improve the capacity of skeletal muscle to make use of insulin.
What we discover about how those proteins work and how to manipulate them ultimately will help to develop innovative cellular treatments for fighting type 1 and type 2 diabetes, in collaboration with our scientific and clinical colleagues at City of Hope. Other projects in the Thurmond Lab focus on how these multitaskers can improve islet cell transplantation—a promising investigational treatment for type 1 diabetes—and can serve as biomarkers for detecting the development of diabetes.