Cancer and Diet
Current cancer treatment with drugs completely overlooks the impact of diet composition on cancer treatment outcomes. Research from Shiuan Chen, Ph.D., professor and chair, Department of Cancer Biology, has found that many drugs will modulate how cancer cells utilize nutrients, such as proteins, carbohydrates and fats. mTOR is a key factor that regulates food intake, a nutrient sensor and a major target for cancer treatment. Dr. Chen and his team are studying the best diets for successful cancer treatment outcomes using mTOR inhibitors. They are currently studying the impact of high protein diets on ER+ and triple negative breast cancer, and in animal studies, have found that a high protein diets may decrease tumor growth.