An NCI-designated Comprehensive Cancer Center
The Cytogenetics Shared Research Core Facility provides cytogenetic and molecular cytogenetic assays to researchers at City of Hope and outside facilities.  Primary services include conventional and 24-color karyotyping for both human and mouse specimens, fluorescence in situ hybridization (FISH) assays for aneuploidy, gene tracking, and gene alterations on both archival and fresh tissue, targeted genotype/phenotype FISH assays, custom probe development for human and mouse model systems, gene integration/mapping studies, as well as high resolution genomic analyses using Thermo Fisher CytoScan and OncoScan microarrays.  We provide complete service from sample submission through analysis and interpretation, depending on your research needs.

Meet the Team

Abstract for Grants

The City of Hope Shared Resources Cytogenetics Core facility provides classic and molecular (FISH and MCA) cytogenetic services to City of Hope and Beckman Research Institute scientific investigators, as well as outside researchers and institutions.
 
The Core facility will also provide training, cell line tumor banking, and consultation services for applied molecular cytogenetic testing.

Publications

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Duplex DNA from Sites of Helicase-Polymerase Uncoupling Links Non-B DNA Structure Formation to Replicative Stress
1. Amparo C, Clark J, Bedell V, Murata-Collins JL, Martella, M, Pichiorri, F, Warner EF, Abdelhamid M, Waller ZAE, Smith SS. Cancer Genomics & Proteomics. 2020; 17:1-15. DOI: 10.21873/cgp.200xx.