Recent Projects

2017
 
Wong P, Li L, Chea J, Delgado MK, Crow D, Poku E, Szpikowska B, Bowles N, Channappa D, Colcher D, Wong JYC, Shively JE, Yazaki, PJ. 2017.  PET imaging of 64Cu-DOTA-scFv-anti-PSMA lipid nanoparticles (LNPs): Enhanced tumor targeting over anti-PSMA scFv or untargeted LNPs.  Nuclear Medicine and Biology 47:62–68
 
Tiet P, Clark KC, McNamara II JO, Berlin JM. 2017. Colorimetric detection of Staphylococcus aureus contaminated solutions without purification. Bioconjug Chem 28:183-193
 
2016
 
Kato M, Wang M, Chen Z, Bhatt K, Oh HJ, Lanting L, Deshpande S, Jia Y, Lai JYC, O’Connor CL, Wu WF, Hodgin JB, Nelson RG, Bitzer M , Natarajan R. 2016.  An endoplasmic reticulum stress-regulated lncRNA hosting a microRNA megacluster induces early features of diabetic nephropathy.  Nat Commun 7:e12864
 
Cheng CT, Kuo CY, Ouyang C, Li CF, Chung Y, Chan DC, Kung HJ, Ann DK.  2016.  Metabolic stress-induced phosphorylation of KAP1 Ser473 blocks mitochondrial fusion in breast cancer cells. Cancer Res 76:5006-5018
 
Mooney R, Schena E, Saccomandi P, Zhumkhawala A, Aboody K, Berlin JM.  2016.  Gold nanorod-mediated near-infrared laser ablation: in vivo experiments on mice and theoretical analysis at different settings. Int J Hyperthermia 20:1-10
 
Jin L, Gao D, Feng T, Tremblay JR, Ghazalli N, Luo A, Rawson J, Quijano JC, Chai J, Wedeken L, Hsu J, LeBon J, Walker S, Shih HP, Mahdavi A, Tirrell DA, Riggs AD, Ku HT. 2016. Cells with surface expression of CD133(high)CD71(low) are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas. Stem Cell Research 16:40-53
 
2015
 
Ghazalli N, Mahdavi A, Feng T, Jin L, Kozlowski MT, Hsu J, Riggs AD, Tirrell DA, Ku HT. 2015. Postnatal pancreas of mice contains tripotent progenitors capable of giving rise to duct, acinar, and endocrine cells in vitro. Stem Cells and Development 24:1995-2008
 
Fong MY, Zhou W, Liu L, Alontaga AY, Chandra M, Ashby J, Chow A, O'Connor ST, Li S, Chin AR, Somlo G, Palomares M, Li Z, Tremblay JR, Tsuyada A, Sun G, Reid MA, Wu X, Swiderski P, Ren X, Shi Y, Kong M, Zhong W, Chen Y, Wang SE. (2015) Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis. Nat Cell Biol 17:183-194
 
Van Haute D, Longmate JM, Berlin JM. 2015. Controlled assembly of biocompatible metallic nanoaggregates using a small molecule crosslinker. Advanced Materials 27:5158-5164
White EE, Pai A, Weng Y, Suresh AK, Van Haute D, Pailevanian T, Alizadeh D, Hajimiri A, Badie B, Berlin JM. 2015. Functionalized iron oxide nanoparticles for controlling the movement of immune cells. Nanoscale 7:7780-7789
 

2014

LaBarge S, McDonald M, Smith-Powell L, Auwerx J, Huss JM. 2014. Estrogen-related receptor-α (ERRα) deficiency in skeletal muscle impairs regeneration in response to injury. FASEB J 28:1082-1097

Mooney R, Weng Y, Garcia E, Bhojane S, Smith-Powell L, Kim SU, Annala AJ, Aboody KS, Berlin JM. 2014. Conjugation of pH-responsive nanoparticles to neural stem cells improves intratumoral therapy. J Control Release 191: 82-89.

Mooney R, Weng Y, Tirughana-Sambandan R, Valenzuela V, Aramburo S, Garcia E, Li Z, Gutova M, Annala AJ, Berlin JM, Aboody KS. 2014. Neural stem cells improve intracranial nanoparticle retention and tumor-selective distribution. Future Oncol 10(3): 401-415.

Chow A, Zhou W, Liu L, Fong MY, Champer J, Van Haute D, Chin AR, Ren X, Gugiu BG, Meng Z, Huang W, Ngo V, Kortylewski M, Wang SE. 2014. Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB. Sci Rep 4: 5750

Morgan-Bathke M, Hill GA, Harris ZI, Lin HH, Chibly AM, Klein RR, Burd R, Ann DK, Limesand KH. 2014. Autophagy correlates with maintenance of salivary gland function following radiation. Sci Rep 4: 5206.

Zhou W, Fong MY, Min Y, Somlo G, Liu L, Palomares MR, Yu Y, Chow A, O'Connor ST, Chin AR, Yen Y, Wang Y, Marcusson EG, Chu P, Wu J, Wu X, Li AX, Li Z, Gao H, Ren X, Boldin MP, Lin PC, Wang SE. 2014. Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis. Cancer Cell 25: 501-515.

Jin L, Feng T, Zerda R, Chen CC, Riggs AD, Ku HT. 2014. In vitro multilineage differentiation and self-renewal of single pancreatic colony-forming cells from adult C57BL/6 mice. Stem Cells Dev 23: 899-909.

Jin L, Feng T, Chai J, Ghazalli N, Gao D, Zerda R, Li Z, Hsu J, Mahdavi A, Tirrell DA, Riggs A D, Ku H T. 2014. Colony-forming progenitor cells in the postnatal mouse liver and pancreas give rise to morphologically distinct insulin-expressing colonies in three-dimensional cultures. Rev Diabet Stud. 11: 35-53.

Qiu F, Chen YR, Liu X, Chu CY, Shen LJ, Xu J, Gaur S, Forman HJ, Zhang H, Zheng S, Yen Y, Huang J, Kung HJ, Ann DK. 2014. Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells. Sci Signal. 7(319): ra31.

2013

Gutova, M., Frank, J.A., D’Apuzzo, M.,  Khankaldyyan, V., Gilchrist, M., Annala, A.J., Metz, M.Z., Abramyants, Y., Herrmann, K.A., Ghoda, L.Y., Najbauer, J., Brown, C.E., Blanchard, M.S., Lesniak, M.S., Kim, S.U., Barish, M.E., Aboody, K.S., Moats, R.A. (2013)  MRI tracking of Ferumoxytol-labeled human neural stem cells: Studies leading to clinical use. Stem Cells Translational Medicine 2(10): 766-775

Morgan-Bathke M, Lin HH, Chibly AM, Zhang W, Sun X, Chen CH, Flodby P, Borok Z, Wu R, Arnett D, Klein RR, Ann DK. 2013. Deletion of ATG5 shows a role of autophagy in salivary homeostatic control. J Dental Res 92: 911-917.

Jin, L., Feng, T., Shih, H. P., Zerda, R., Luo, A., Hsu, J., Mahdavi, A., Sander, M., Tirrell, D. A., Riggs, A. D., and Ku, H. T. (2013)  Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel. Proceedings of the National Academy of Sciences of the United States of America 110: 3907-3912.

Zhang, Z. and Shively, J.E. (2013) Acceleration of bone repair in NOD/SCID mice by human monoosteophils, novel LL-37-activated monocytes. PloS One 8(7): e67649.

Nechaev, S., Gao, C., Moreira, D., Swiderski, P., Jozwiak, A., Kowolik, C. M., Zhou, J., Armstrong, B., Raubitschek, A., Rossi, J. J., and Kortylewski, M. (2013)  Intracellular processing of immunostimulatory CpG-siRNA: Toll-like receptor 9 facilitates siRNA dicing and endosomal escape. Journal of Controlled Release : Official Journal of the Controlled Release Society 170: 307-315.

Suresh AK, Weng Y, Li Z, Zerda R, Van Haute D, Williams JC, Berlin JM. (2013)  Matrix metalloproteinase-triggered denuding of engineered gold nanoparticles for selective cell uptake. J Mater Chem B. 1: 2341-2349

Schnarr, K., Mooney, R., Weng, Y., Zhao, D., Garcia, E., Armstrong, B., Annala, A.J., Kim, S.U., Aboody, K.S., Berlin, J.M. (2013)  Gold nanoparticle-loaded neural stem cells for photothermal ablation of cancer. Adv Healthc Mater 2(7): 976-982.