Shen Li, M.D.

888-296-0313
Shen Li, M.D.
Surgical Oncologist
Clinical Expertise
  • Surgical Oncology
Other Languages Spoken
Mandarin
Academic Appointments
  • Assistant Clinical Professor, Department of Surgery
Additional Contacts
  • Referring Physicians Phone
    (847) 746-9990
  • Referring Physicians Fax
    (847) 342-4089
  • Referring Physicians Email
    [email protected]

In his role at City of Hope® Cancer Center Chicago, Surgical Oncologist Shen Li, M.D., treats a wide range of conditions, specializing in complex gastrointestinal cancers, soft tissue disease and hepato-pancreato-biliary conditions and using advanced and minimally invasive techniques. When collaborating with his patients’ multidisciplinary cancer care team, Dr. Li brings compassion, clinical expertise and a patient-centered approach to making treatment decisions. 

Dr. Li earned his medical degree at the University of Pittsburgh School of Medicine in Pennsylvania, before completing a residency in general surgery at Beth Israel Deaconess Medical Center in Boston. In addition to a research fellowship at Massachusetts General Hospital in Boston, he completed a fellowship in surgical oncology at the University of Chicago Medical Center. 

A physician-scholar, Dr. Li has written or co-written more than a dozen articles on topics including surgical treatments and genetic therapies for liver and pancreatic cancer. A board-certified surgeon, he is a member of the American College of Surgeons, the American Association for the Study of Liver Disease and the American Association for Cancer Research. His work has been published in Nature, Gut, JCI Insight and The FACEB Journal. 

While Dr. Li performs all procedures at our hospital in Lake County, he also provides surgical consultations at our outpatient care locations in downtown Chicago and the North Shore.

Location

Education & Experience

Board Certifications
  • General Surgery – American Board of Surgery
Degrees
  • University of Pittsburgh School of Medicine, Pittsburgh, PA
Residency
  • Surgery – Beth Israel Deaconess Medical Center, Boston, MA
Fellowship
  • Research Fellowship – Massachusetts General Hospital, Boston, MA
  • Surgical Oncology – University of Chicago Medical Center, Chicago, IL
     

Awards & Memberships

Memberships

  • American College of Surgeons
  • American Association for the Study of Liver Disease (AASLD)
  • American Association for Cancer Research (AACR)
  • Society of Surgical Alimentary Track (SSAT)
  • Society of Surgical Oncology (SSO)

Publications

  • Perri, G., van Hilst, J., Li, S., Besselink, MG., Hogg, ME., Marchegiani, G., 2023. Teaching modern pancreatic surgery: close relationship between centralization, innovation, and dissemination of care. BJS open, 7(5).
  • Crouchet, E*., Li, S*., Sojoodi, M., Bandiera, S., Fujiwara, N., El Saghire, H., Zhu, S., Qian, T., Rasha, FA., Del Zompo, F., Barrett, SC., Schaeffer, E., Oudot, MA., Ponsolles, C., Durand, SC., Ghoshal S., Arora G., Giannone, F., Chung, RT., Slovic, N., Van Renne, S., Felli, E., Pessaux, P., Lupberger J., Pochet, N., Schuster C., Tanabe, KK., Hoshida, Y., Fuchs, BC., Baumert, TF. 2022. Hepatocellular carcinoma chemoprevention by targeting the angiotensin-converting enzyme and EGFR transactivation. JCI insight, 7(13).
  • Sojoodi, M., Erstad, D.J., Barrett, SC., Salloum, S., Zhu, S., Qian, T., Colon, S., Gale, EM., Jordan, VC., Wang, Y. and Li, S., Ataeina, B., Jalilifiroozinezhad, S., Lanuti, M., Zukerberg, L., Caravan P., Hoshida, Y., Chung, RT., Bhave, G., Lauer, GM., Tanabe KK. 2022. Peroxidasin deficiency re-programs macrophages toward pro-fibrolysis function and promotes collagen resolution in liver. Cellular and Molecular Gastroenterology and Hepatology.
  • Crouchet, E*., Bandiera, S*., Li, S., El Saghire, H., Fernández-Vaquero, M., Riedl, T., Sun, X., Hirschfield, H., Jühling, F. and Zhu, S., Roehlen, N., Ponsolles, C., Heydmann, L., Saviano, A., Qian, T., Venkatesh A., Lupberger J., Verrier, ER., Sojoodi, M., Oudot MA., Duong, FHT., Masia R., Wei L., Thumann Christine., Durand SC., Gonzalez-Motos, V., Heide D., Hetzer J., Hakagawa S., Ono A., Song, WM., Higashi, T., Sanchez, R., Kim, RS., Bian, CB., Kiani, K., Croonenborghs, T., Subramanian, A., Chung, RT., Straub, BK., Schuppan, D., Ankavay, M., Cocquerel, L., Schaeffer, E., Goossens, N., Koh, AP., Mahajan M., Nair, VD., Gunasekaran, G., Schwartz, ME., Bardeesy, N., Shalek, AK., Rozenblatt-Rosen, O., Regev, A., Felli, E., Pessaux, P., Tanabe, KK., Heikenwalder, M., Schuster, C., Pochet, N., Zeisel, MB., Fuchs, BC., Hoshida Y., Baumert, TF.,   2021. A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery. Nature communications, 12(1), pp.1-19.
  • Li, S., Saviano, A., Erstad, D.J., Hoshida, Y., Fuchs, B.C., Baumert, T., Tanabe, KK., 2020. Risk factors, pathogenesis, and strategies for hepatocellular carcinoma prevention: emphasis on secondary prevention and its translational challenges. Journal of Clinical Medicine, 9(12), p.3817.
  • Hexiao, T., Yuquan, B., Lecai, X., Yanhong, W., Li, S., Weidong, H., Ming, X., Xuefeng, Z., Gaofeng, P., Li, Z. and Minglin, Z., 2021. Knockdown of CENPF inhibits the progression of lung adenocarcinoma mediated by ERβ2/5 pathway. Aging (albany NY), 13(2).
  • Erstad DJ, Sojoodi M, Taylor MS, Clavijo Jordan V, Farrar CT, Axtell AL, Rotile NJ, Jones C, Graham-O'Regan KA, Ferreira DS, Michelakos T, Kontos F, Chawla A, Li S, Ghoshal S, Chen YI, Arora G, Humblet V, Deshpande V, Qadan M, Bardeesy N, Ferrone CR, Lanuti M, Tanabe KK, Caravan P, Fuchs BC. Fibrotic Response to Neoadjuvant Therapy Predicts Survival in Pancreatic Cancer and is Measurable with Collagen-Targeted Molecular MRI. Clinical Cancer Research. 2020 Jul 1.
  • Li S, Alapati A, Riba L, Fleishman A, James TA, Sharma R. Delayed Adjuvant Hormonal Therapy and Its Impact on Mortality in Women with Breast Cancer. Breast Journal. 2020 May;26(5):952-959.
  • Li S*, Jühling F*, Hamdane N*, Crouchet E*, El Saghire H, Mukherji A, Fujiwara N, Oudot MA, Thumann C, Saviano A, Roca Suarez AA, Goto K, Masia R, Sojoodi M, Arora G, Aikata H, Ono A, Tabrizian P, Schwartz M, Polyak SJ, Davidson I, Schmidl C, Bock C, Schuster C, Chayama K, Pessaux P, Tanabe KK, Hoshida Y, Zeisel MB, Duong FH, Fuchs BC, Baumert TF. Targeting Clinical Epigenetic Reprogramming for Chemoprevention of Metabolic and viral hepatocellular Carcinoma 
    Gut. 2021 Jan; 70(1): 157-169.
  • Erstad, DJ., Razavi, AA., Li, S., Tanabe, KK., Fuchs, BC., 2019. Prevention strategies for hepatocellular carcinoma. Hepatocellular carcinoma: Translational precision medicine approaches, pp.255-289.
     

Ratings & Reviews

Ratings and reviews below are gathered from the Press Ganey Clinician and Group Consumer Assessment of Healthcare Providers and Systems (CG CAHPS) survey. CG CAHPS is a standardized survey that is used to measure a patient's experience in the physician office setting. Ratings are an average of all responses to questions about a provider's care, with five stars being the highest.
4.8
Provider explain in way you understand
4.8
Provider listen carefully to you
4.8
Rate provider 0-10
4.7
Recommend this provider office
4.7
Show respect for what you say
4.7
Spend enough time with you
4.6
Know important info medical history
04/07/25
Dr. Li has been an active listener to all of my many complications. He talks to whoever can help in my care, other Dr, surgeons & relies heavily on the expertise of his team which makes me feel very comfortable in the direct care I am receiving. That is not to say any of this is easy & they have seen me emotional on many levels. The care that they show keeps me coming back due to the complexity of my case. - Verified patient