Diagnosed With Cancer? Don’t Wait.
At City of Hope®, we’re redefining cancer care in the Chicagoland and surrounding areas, with a team of experts delivering leading-edge treatments and whole-person supportive care at lifesaving speed. With locations in Lake County, downtown Chicago and the North Shore, our multidisciplinary teams provide access to appointments within 24 hours, same-day diagnostics and 48-hour pathology results.
Here, top oncologists, Magnet®-designated nurses, expert genetic counselors and other clinical team members unite to create a personalized treatment plan for you, blending leading-edge research with compassionate care. From diagnosis to survivorship, everything you need is under one roof — so you can focus on healing, not waiting.
Why Choose City of Hope Illinois Locations for Cancer Treatment?
At City of Hope Illinois, we know every cancer diagnosis is unique — which is why we pair leading-edge treatments that target cancer down to the DNA with compassionate care tailored to your individual hopes, needs and goals.
Our nationally recognized programs include the only blood cancer program to offer the full spectrum of stem cell transplants midway between Chicago and Milwaukee, advanced gynecological cancer surgery, and a Certified Quality Breast Cancer of Excellence, one of only ten comprehensive programs in the nation and the only location in Illinois recognized for the highest clinical standards by the National Quality Measures for Breast Centers program. Alongside treatment, we provide comprehensive supportive care to help manage both physical and emotional side effects. From gathering medical records and verifying insurance to scheduling appointments, our team ensures a seamless, coordinated experience so you can focus on healing.
When you choose City of Hope, you gain access to:
An expert multidisciplinary team recognized for clinical excellence with nearly four decades of accreditation by the Commission on Cancer
A longstanding blood cancer program that was recognized by U.S. News & World Report’s 2025-26 ratings as “high performing” in the field of leukemia, lymphoma and myeloma
An award-winning gynecologic cancer surgery program that was recognized by U.S. News & World’ Report’s 2024-2025 “Best Hospital” list as “high performing” in gynecologic surgery
Press Ganey Guardian of Excellence and Pinnacle of Excellence Awards for our strong patient satisfaction ratings
Learn more about City of Hope Chicago's recognitions, accreditations and awards
City of Hope Cancer Center Chicago
City of Hope Cancer Center Chicago is part of one of the largest cancer research and treatment organizations in the United States. Just minutes over the Wisconsin/Illinois state line in northeastern Lake County, our hospital is located at 2520 Elisha Avenue, Zion, IL 60099.
Advanced Treatment in Northern Illinois for All Cancer Stages and Types
Our Illinois clinical teams focus exclusively on cancer treatment. It's all we do. With extensive expertise in common and rare cancers, our specialists will deliver a precise, disease-specific care plan tailored to you. Patients like you across Northern Illinois benefit from access to experts in blood, breast, lung, gastrointestinal, gynecologic, prostate and skin cancers, each offering advanced treatment options and innovative approaches.
Our Illinois clinical team understands the unique challenges of each cancer type and are committed to providing personalized treatment plans designed for the best possible outcomes.
Our fully accredited Blood Cancer Center treats all types of blood cancers, including leukemia, lymphoma and multiple myeloma. We’re also the only location midway between Chicago and Milwaukee that offers the full range of stem cell transplantation services.
As the only Certified Quality Breast Center of Excellence in Illinois, we customize each patient’s treatment plan to her individual needs and cancer. Personalized options may include breast-conserving surgery, reconstructive options and radiation therapy that protects the heart.
Driven by speed, our multidisciplinary team of experts delivers a lung cancer diagnosis and treatment plan in as little as one week. Focused on precision and innovation, we offer minimally invasive options to aggressively treat lung cancer.
Our team of gastroenterology experts provides precise treatments for colorectal, stomach, pancreatic, liver and esophageal cancers. Using advanced technologies, including AI, we aim to aggressively treat your cancer while improving your quality of life.
Recognized for excellence in gynecologic cancer surgery, our experts provide personalized treatments for cervical, ovarian, fallopian tube, uterine and vaginal cancers. Our skilled team excels in advanced and robotic surgery.
Our prostate cancer program combines advanced treatment options and technologies with a strong focus on men’s sexual health both during and after treatment. In addition to surgery and radiation therapy, we also provide innovative options like Pluvicto® for recurrent and metastatic disease.
Our expert clinical care team brings together innovation and collaboration to treat all stages of skin cancer. This encompasses recurrent and metastatic disease and skin reactions from certain cancer treatments therapies, such as immunotherapy and radiation.
Become a Patient at City of Hope
Explore how to become a patient at City of Hope — whether you’re newly diagnosed, seeking a second opinion or exploring advanced treatment options. Learn about our expertise in complex cancers and how we support you through insurance and referrals, and hear inspiring stories from former patients. Start here to feel supported, informed and empowered in your care.
We Coordinate the Details, Supporting You Every Step of the Way
Navigating cancer care can feel overwhelming, but City of Hope's three Illinois locations are here to make the process easier for you and your loved ones. From verifying your insurance and coordinating appointments to arranging travel support for eligible patients*, our team ensures the details are taken care of. You'll also have a dedicated nurse navigation team by your side to answer questions and guide you with confidence. Whether you live nearby or are traveling from across the Midwest or beyond, City of Hope is ready to support you every step of the way.
Get Peace of Mind With a Second Opinion
Many patients make a final decision after seeking a second opinion on their diagnosis and treatment plan. At City of Hope — a national network of cancer experts who collaborate coast to coast — we understand that you need accurate answers, quickly.
That’s why, when you seek a second opinion at one of our locations, our cancer experts work to perform the comprehensive evaluation you need, with the urgency you deserve. When you make a second opinion appointment with us, you’ll get results you can trust, delivered by a team of specialists who will collaborate on treatment recommendations personalized to your individual diagnosis, needs and preferences.
Fast, easy insurance verification.
Meet Our Cancer Center Clinical Experts
Choosing the right doctor and care team is one of the most important decisions you’ll make when you’re diagnosed with cancer. At our Illinois locations, our physicians are not just experts in their fields with the experience of working with cancer patients every day — they’re also dedicated to providing compassionate, whole-person care to support you emotionally and physically.
Meet our local clinical leaders:
Dr. Buttin treats all gynecologic cancers and specializes in minimally invasive surgical techniques, including robotic surgery. She has performed over 1,500 robotic cases to date.
As president of the medical staff at City of Hope Chicago, Dr. Khan provides leadership to our Illinois medical staff, guides protocols, ensures standard-of-care guidelines are consistently met and exceeded, and helps recruit high-quality physicians.
Dr. Rodriguez has over 20 years of experience treating blood cancer and is an expert in bone marrow transplantation. He has performed over 2,500 transplant procedures.
As chief clinical officer at City of Hope Chicago, Dr. Stadler ensures operational excellence in physician recruitment and clinical care, while focusing on expanding access to innovative cancer treatments. He holds over 30 years of experience in academic medicine in the Chicagoland area.
Dr. Winchester is a surgical oncologist with nearly three decades of surgical experience, including procedures for breast, skin and thyroid cancers.
National Cancer Care Expertise is Close to Home
Our locations in Northern Illinois, including Lake County, downtown Chicago and the North Shore are part of our national network of nearly 2,100 City of Hope physicians, scientists and researchers at the forefront of cancer research and treatment, striving to provide tomorrow’s advances in cancer care to those who need them today.
Hope Matters, Chicago – Your Local Cancer Care News
Welcome to our Midwest cancer care blog – your go-to resource for the latest information on cancer prevention, treatment options and cancer trends in Illinois and surrounding states. Join us as we navigate the journey of cancer care together, providing you with the knowledge and support you need.
