Small intestine cancer is quite rare, with about 9400 new cases diagnosed each year in the U.S. 

If you've been diagnosed with cancer of the small intestine, talk to us. It's important to learn about your options and take action right away. Survival rates for small intestine cancer are encouraging; they've doubled over the past 40 years. Early detection can make a significant difference.

Our world-class team of specialists can answer your questions, address your concerns, and deliver a personalized treatment plan with the most innovative, cutting-edge therapies available anywhere.

At City of Hope, we are committed to treating the whole person, body and soul. We have an unmatched reputation for coordinated, compassionate care. We bring together a broad array of cancer expertise from multiple disciplines, all under one roof:

  • State-of-the-art screenings and diagnostic tools including endoscopy, CT scans and genetic testing
  • Minimally-invasive, robotically-assisted surgery for fewer complications and faster recovery
  • Surgical specialists dedicated to preserving quality of life
  • Ultra-precise radiation therapy to target tumors and preserve healthy tissue
  • Targeted drugs and drug combinations for greater effectiveness and fewer side effects
  • Pioneering drug research and clinical trials

Plus, your supportive care continues long after treatment is complete. Our specialists will help you adjust to post-treatment diet and lifestyle changes, and our unique family and survivorship programs will assist your loved ones.

Nationally Ranked Cancer Center

City of Hope is a recognized leader in small intestine cancer research and treatment. We are designated a Comprehensive Cancer Center by the National Cancer Institute, and for over a decade, U.S. News & World Report has named City of Hope one of the top cancer hospitals in America.

Learn more about small intestine cancer.

Care Team

City of Hope’s renowned physicians and researchers utilize the latest in technology and innovation to treat cancer, coupled with our enduring belief in providing unparalleled compassionate care. If you have been diagnosed with small intestine cancer or are looking for a second opinion consultation about your treatment, request an appointment online or contact us at 800-826-HOPE. Please visit Making Your First Appointment for more information.

Yi-Jen Chen, M.D., Ph.D.

Clinical Specialties:

  • Radiation Oncology
Vincent Chung, M.D., F.A.C.P.

Clinical Specialties:

  • Medical Oncology
Donald S. David, M.D., F.A.C.G.

Clinical Specialties:

  • Gastroenterology
Marwan G. Fakih, M.D.

Clinical Specialties:

  • Medical Oncology
Jonathan Kessler, M.D.

Clinical Specialties:

  • Diagnostic Radiology
  • Interventional Radiology
Lily Lai, M.D., F.A.C.S.

Clinical Specialties:

  • Surgical Oncology
Dean W. Lim, M.D.

Clinical Specialties:

  • Medical Oncology
Laleh Melstrom, M.D.,M.S., F.A.C.S.

Clinical Specialties:

  • Hepato-Pancreato-Billiary (HPB) Surgery
  • Surgical Oncology
Sentovich-Stephen M.
Stephen M. Sentovich, M.D., MBA

Clinical Specialties:

  • Colon and Rectal Surgery

Tests & Treatments

Every patient is different, with different needs. City of Hope treats you as a valued individual. Our entire team works together to bring you precise, state-of-the-art surgical, chemotherapy, radiation and other options that will deliver the best outcome for you. We support you every step of the way, both during treatment and long after, helping you and your loved ones manage your recovery.

Learn more about treatment options for small intestine cancer.

Clinical Trials

At City of Hope, we offer access to drug, surgical and other clinical trials aimed at improving survival rates and enhancing quality of life. Our latest research ranges from enhancing PET scans using a drug that targets a specific protein, to studying the impact of a cancer diagnosis on caregivers and alleviating that impact through a Caregiver Intervention Program.

Browse through some of our clinical trials and research projects here:


When you come to City of Hope, you automatically gain access to an unparalleled array of support services to help you and your family cope with each challenge in your small intestine cancer diagnosis and treatment. We can help with all of these concerns, and more:

  • Managing pain, fatigue, nausea
  • Adjusting to new diet and lifestyle habits
  • Your emotional, social and spiritual well-being
  • Palliative care
  • Staying healthy and active
  • Healthy cooking and eating
  • Healing arts
  • Caregiver skills
  • Dealing with family, school and work stress
  • Navigating the health care system

Learn more about these resources at our Living with Cancer or Supportive Care Medicine sites.

Support the Small Intestine Cancer Program

It takes the help of a lot of caring people to make hope a reality for our patients. City of Hope was founded by individuals' philanthropic efforts more than 100 years ago. Their efforts − and those of our supporters today − have built the foundation for the care we provide and the research we conduct. It enables us to strive for new breakthroughs and better therapies − helping more people enjoy longer, better lives.

For more information on supporting this specific program, please contact us below.

Joe Komsky
Senior Development Officer
Phone: 626-218-6291
Email: [email protected]

Or, you can make a gift to support all the research at City of Hope by donating online.

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