Myeloma is a relatively rare cancer that strikes an estimated 26,000 Americans each year. If you've been diagnosed with myeloma, talk to us. It's important to learn about your options as soon as you can. Our world-class team of myeloma specialists can answer your questions, address your concerns, and deliver a personalized treatment plan with the most innovative, cutting-edge therapies available anywhere.

At City of Hope's Judy and Bernard Briskin Center for Multiple Myeloma Research, we are committed to treating the whole person, body and soul. We have an unmatched reputation for coordinated, compassionate care. We bring together a broad array of myeloma expertise from multiple disciplines, all under one roof:

  • State-of-the-art diagnostic tools
  • Pioneering drug research and clinical trials
  • Unique chemotherapy, immunotherapy, radiation and transplant options, including T-cell therapy and less-intensive “mini” stem cell transplants for older patients
Plus, your care continues long after treatment is complete, with our unique family and survivorship programs.
City of Hope is the only southern California member of the Multiple Myeloma Research Consortium, dedicated to rapidly bringing the most promising treatments to patients. We are recognized internationally for our research and breakthrough treatments. We operate one of the largest transplant centers in the U.S., producing some of the consistently best outcomes. We are designated a Comprehensive Cancer Center by the National Cancer Institute, and for over a decade, U.S. News & World Report has named City of Hope one of the top cancer hospitals in America.

If you have been diagnosed with myeloma or multiple myeloma or are looking for a second opinion consultation about your treatment, request an appointment online or contact us at 800-826-HOPE. Please visit Making Your First Appointment for more information.


Care Team

City of Hope’s renowned physicians and researchers utilize the latest in technology and innovation to treat cancer, coupled with our enduring belief in providing unparalleled compassionate care.

Stephen J. Forman, M.D., F.A.C.P.

Clinical Specialties:

  • Hematology/Oncology
Generic Faculty Photo
Chatchada Karanes, M.D.

Clinical Specialties:

  • Hematology/Oncology
Amrita Krishnan, M.D., F.A.C.P.

Clinical Specialties:

  • Hematology/Oncology
Pablo M Parker, M.D.

Clinical Specialties:

  • Hematology/Oncology
Leslie L Popplewell, M.D., F.A.C.P.

Clinical Specialties:

  • Hematology/Oncology/Internal Medicine
Eileen P. Smith, M.D.

Clinical Specialties:

  • Hematology/Oncology
George Somlo, M.D.

Clinical Specialties:

  • Medical Oncology
  • Hematology & Hematopoietic Cell Transplantation
Gargi Upadhyaya, M.D.

Clinical Specialties:

  • Medical Oncology
Jeffrey Y.C. Wong, M.D.

Clinical Specialties:

  • Radiation Oncology

Tests & Treatments

At City of Hope, we were among the first to build and develop a Bone Marrow and Stem Cell Transplant program which has performed more than 12,000 procedures since 1976. City of Hope has been recognized for superior survival outcomes for 10 consecutive years—the only transplant center in the United States with such an achievement.

Beyond transplants, we also offer the broadest range of myeloma treatments available, including adoptive T-cell therapy, helical TomoTherapy and monoclonal antibody therapy.

Every patient is different, with different needs. At City of Hope, we treat you as a valued individual. Our entire team works together to bring you precise, state-of-the-art chemotherapy, immunotherapy, radiation and transplant options that will deliver the best outcome for you. We support you every step of the way, both during treatment and long after, helping you and your loved ones manage your recovery.

Learn more about treatment options for myeloma, including chemotherapy, radiation and bone marrow / stem cell transplantation.

Clinical Trials

City of Hope is a recognized leader in myeloma research. We offer access to dozens of clinical trials and new therapies not always available elsewhere. Our latest research is focused on new drugs and drug combinations that target and attack relapsed myeloma which has become resistant to first-line treatment.
Browse through some of our clinical trials and research projects here.


When you come to City of Hope, you automatically gain access to an unparalleled array of support services to help you and your family take each step in your myeloma and multiple myeloma journey. We can help with all of these concerns, and more:
  • Managing side effects
  • Pain management
  • Navigating the health care system
  • Your emotional, social and spiritual health
  • Staying healthy and active
  • Healthy cooking and eating
  • Healing arts
  • Caregiver skills
  • Dealing with family, school or work stress
Learn more about these resources at our Living with Cancer or Supportive Care Medicine sites.
Additional Resources:
Support the Judy and Bernard Briskin Center for Multiple Myeloma Research
We deliver exquisite care at the leading edge of cancer treatment. It takes the help of a lot of caring people to make hope a reality for our patients. City of Hope was founded by individuals' philanthropic efforts over 100 years ago. Their efforts - and those of our supporters today - have built the foundation for the care we provide and the research we conduct.
For more information on supporting this specific program, please contact

Amy M. Cook, Ph.D.
Associate Director, Philanthropy
Direct: 626-218-6228
Or, you can make a gift to support all the research at City of Hope by donating online.


An Expert's Voice

City of Hope experts cover prevention, screening, treatment and other cancer topics on City of Hope’s Breakthrough’s blog.

  • ASCO 2015: Cancer research brings new and better therapies to patients May 26, 2015 | by Nicole Levine
  • Adoptive T cell therapy: Harnessing the immune system to fight cancer August 15, 2014 | by hso
  • Multiple myeloma and bone health: What patients need to know August 06, 2014 | by hso
  • Cancer of the breast, colon, lungs ... Putting research in perspective March 03, 2014 | by tdennis
  • Meet our doctors: Hematologist Leslie Popplewell on clinical trials March 02, 2014 | by Kim Proescholdt
  • Lab matches stem cell donors with bone marrow transplant patients July 22, 2013 | by djoy
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