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Cancer Immunotherapeutics and Tumor Immunology



An Overview


The Division of Cancer Immunotherapeutics and Tumor Immunology (CITI) is led by City of Hope's preeminent researchers and physicians, CITI's chair is Andrew Raubitschek, M.D., with Michael Jensen, M.D. as the Associate Chair, and Stephen Forman, M.D., as the Director of Clinical Research.

Immunotherapy, a powerful weapon against cancer because of its potential to exploit the body's natural defenses against infection, has been called the "fourth modality" of cancer treatment by the American Cancer Society. We want to make it a primary cure.

Currently, T-cell therapy and radioimmunotherapy offer renewed hope to people who have exhausted other treatment options. They are also effective for eliminating microscopic residual disease which can lead to cancer recurrence, even after chemotherapy, radiation therapy and surgery have been successful. The goal of CITI is to one day advance immunotherapeutic cures that will eliminate these more debilitating forms of treatment.

 

Cancers Being Targeted

Breast Cancer: diagnosed in more than 200,000 women every year.

Colorectal Cancer: caused more than 55,000 deaths in 2005 alone.

Gliomas: the deadliest and most common type of brain cancer.

Leukemia: accounts for a third of all cancers in children under the age of 15.

Lung Cancer: takes more lives than colorectal, breast and prostate cancers combined.

Lymphoma: the fifth most common cancer in this country, affecting both adults and children.

Medulloblastomas: represent approximately 15% of childhood brain tumors.

Neuroblastoma: diagnosed in children less than one year old in almost half of all cases.

Ovarian Cancer: will be diagnosed in more than 25,000 American women.

Prostate Cancer:is the second leading cause of cancer death among American men, claiming more than 30,000 lives every year.
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