A National Cancer Institute-designated Comprehensive Cancer Center

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Clinical Cancer Genetics

 
 
 Mission Statement:
 The City of Hope Division of
 Clinical Cancer Genetics is
 committed to being a national
 leader in the advancement
 of cancer genetics, screening
 and prevention, through
 innovative patient care,
 research and education.
 
 
In light of a growing body of research confirming that many common cancers, including breast, ovarian, and colorectal cancer, are hereditary, the Division of Clinical Cancer Genetics (CCG) Cancer Screening & Prevention Program helps people understand their personal cancer risk profiles, offering a comprehensive cancer risk assessment that takes into account family history and genetics, along with environmental and lifestyle factors. With this information, people can take proactive steps to “outsmart cancer.”
 
 
 
 
The division’s Cancer Genetics Education Program (CGEP) offers courses and professional development tools designed to further health care professionals’ understanding of cancer genetics.
 
 

Major initiatives include:

The Intensive Course (IC) promotes community-based, practitioner-level competence in the selection, application and interpretation of genetic testing in order to provide these critical services in underserved areas.
 
 
 
The Clinical Cancer Genetics Community of Practice (CCGCoP) is a network of clinicians who have graduated from the IC and/or the Cancer Genetics Career Development Program (CGCDP), along with members of the CCGCRN. Those who are part of this unique community have access to collaborators and professional support from other community members, and to enhanced continuing professional development activities offered by CCG.
 
 
 
In the Cancer Genetics Career Development Program, outstanding post-graduate research scientists receive training with a focus on cutting edge genetic and genomic technology. Graduates of this program continue their work in cancer genetics with the goal of reducing the burden of cancer among those at highest risk.
 
 
 
Clinical cancer genetics research at City of Hope investigates multiple approaches that utilize the latest findings in cancer genetics in order to improve the prevention, treatment, and support of those with hereditary cancers.
 
 
 
Major initiatives include:
 
The CCG molecular genetics research laboratory uses a multitude of research tests such as MLPA, long range PCR and next generation sequencing as well as a variety of state of the art equipment to prescreen high risk patients for mutations in cancer predisposition genes such as BRCA1, BRCA2 and RAD51. Specific equipment available in the laboratory include:  -Sequenom MassArray Analyzer (MALDI-TOF Mass spectrometry) -Sequenom MassArray Robotic Nanodispenser -Ion Torrent Personal Genome Machine -Ion One Touch -Nanodrop 2000c spectrophotometer -Qubit 2.0 Fluorometer -ABI 3130xl Genetic Analyzer -Veriti 96 well thermocyclers -Gene Amp 9700 PCR systems
 
 
 
 
An essential but often unmet aspect of providing quality care to persons affected by cancer or those at hereditary cancer risk is addressing their psychosocial needs. As such, understanding and minimizing the negative impact of hereditary cancer risk on persons' lives is the focus of the CCG Clinical and Behavioral Research program. The program studies health-related behaviors, quality of life (including emotional, psychological and basic daily living needs), and ethical, legal, and social issues, by going directly to the source--our patients and their family members.
 
 
 
 
An integral component of the research program is the Cancer Genetics Community Research Network (CCGCRN), a prospective research registry protocol initiated at City of Hope as a biospecimen repository with associated personal and family medical history, and psychosocial and clinical follow-up data collection. Collaborating community-based oncogenetic practice sites across the U.S. and Latin America are recruiting thousands of genetic cancer risk assessment patients annually.
 
 
 
 
 
In addition, CGEP staff participate in educational outreach to medical groups, hospital medical staffs and other community health care professionals. The program is supported in part by the National Cancer Institute and the California Research Program.
 

Clinical Cancer Genetics

Clinical Cancer Genetics

 
 
 Mission Statement:
 The City of Hope Division of
 Clinical Cancer Genetics is
 committed to being a national
 leader in the advancement
 of cancer genetics, screening
 and prevention, through
 innovative patient care,
 research and education.
 
 
In light of a growing body of research confirming that many common cancers, including breast, ovarian, and colorectal cancer, are hereditary, the Division of Clinical Cancer Genetics (CCG) Cancer Screening & Prevention Program helps people understand their personal cancer risk profiles, offering a comprehensive cancer risk assessment that takes into account family history and genetics, along with environmental and lifestyle factors. With this information, people can take proactive steps to “outsmart cancer.”
 
 
 
 
The division’s Cancer Genetics Education Program (CGEP) offers courses and professional development tools designed to further health care professionals’ understanding of cancer genetics.
 
 

Major initiatives include:

The Intensive Course (IC) promotes community-based, practitioner-level competence in the selection, application and interpretation of genetic testing in order to provide these critical services in underserved areas.
 
 
 
The Clinical Cancer Genetics Community of Practice (CCGCoP) is a network of clinicians who have graduated from the IC and/or the Cancer Genetics Career Development Program (CGCDP), along with members of the CCGCRN. Those who are part of this unique community have access to collaborators and professional support from other community members, and to enhanced continuing professional development activities offered by CCG.
 
 
 
In the Cancer Genetics Career Development Program, outstanding post-graduate research scientists receive training with a focus on cutting edge genetic and genomic technology. Graduates of this program continue their work in cancer genetics with the goal of reducing the burden of cancer among those at highest risk.
 
 
 
Clinical cancer genetics research at City of Hope investigates multiple approaches that utilize the latest findings in cancer genetics in order to improve the prevention, treatment, and support of those with hereditary cancers.
 
 
 
Major initiatives include:
 
The CCG molecular genetics research laboratory uses a multitude of research tests such as MLPA, long range PCR and next generation sequencing as well as a variety of state of the art equipment to prescreen high risk patients for mutations in cancer predisposition genes such as BRCA1, BRCA2 and RAD51. Specific equipment available in the laboratory include:  -Sequenom MassArray Analyzer (MALDI-TOF Mass spectrometry) -Sequenom MassArray Robotic Nanodispenser -Ion Torrent Personal Genome Machine -Ion One Touch -Nanodrop 2000c spectrophotometer -Qubit 2.0 Fluorometer -ABI 3130xl Genetic Analyzer -Veriti 96 well thermocyclers -Gene Amp 9700 PCR systems
 
 
 
 
An essential but often unmet aspect of providing quality care to persons affected by cancer or those at hereditary cancer risk is addressing their psychosocial needs. As such, understanding and minimizing the negative impact of hereditary cancer risk on persons' lives is the focus of the CCG Clinical and Behavioral Research program. The program studies health-related behaviors, quality of life (including emotional, psychological and basic daily living needs), and ethical, legal, and social issues, by going directly to the source--our patients and their family members.
 
 
 
 
An integral component of the research program is the Cancer Genetics Community Research Network (CCGCRN), a prospective research registry protocol initiated at City of Hope as a biospecimen repository with associated personal and family medical history, and psychosocial and clinical follow-up data collection. Collaborating community-based oncogenetic practice sites across the U.S. and Latin America are recruiting thousands of genetic cancer risk assessment patients annually.
 
 
 
 
 
In addition, CGEP staff participate in educational outreach to medical groups, hospital medical staffs and other community health care professionals. The program is supported in part by the National Cancer Institute and the California Research Program.
 
Clinical Cancer Genetics
The City of Hope Division of Clinical Cancer Genetics is committed to being a national leader in the advancement of cancer genetics, screening and prevention, through innovative patient care, research and education.

Contact Us
  • 800-826-HOPE (4673)
  • For more information about the Cancer Screening & Prevention Program, call 626-256-8662, ext. 2.
Beckman Research Institute of City of Hope is internationally  recognized for its innovative biomedical research.
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and professional education.
Learn more about City of Hope's institutional distinctions, breakthrough innovations and collaborations.
City of Hope Breakthroughs
Get the latest in City of Hope's research, treatment and news you can use on our blog, Breakthroughs.
 
 


NEWS & UPDATES
  • Cancer treatments have improved over the years, but one potential source of treatments and cures remains largely untapped: nature. Blueberries, cinnamon, xinfeng, grape seed (and skin) extract, mushrooms, barberry and pomegranates all contain compounds with the potential to treat or prevent cancer. Scientists a...
  • In the U.S., there are more new cases of skin cancer than the combined incidence of cancers of the breast, prostate and lung, according to the American Cancer Society. Each year, 5 million people are treated for skin cancer. Here, Hans Schoellhammer, M.D., assistant clinical professor at City of Hope | Ant...
  • As public health experts know, health improvement starts in the community. Now, City of Hope  has been recognized for its efforts to improve the lives of residents of its own community. The institution will receive funding from the Institute for Healthcare Improvement  to support promising community-based work ...
  • For almost four decades, blood cancer survivors who received bone marrow, or stem cell, transplants have returned to City of Hope to celebrate life, second chances and science. The first reunion, in 1976, was a small affair: spaghetti for a single patient, his brother who served as his donor and those who took ...
  • Chemotherapy is an often-essential component of cancer treatment, attacking cells that divide quickly and helping stop cancer’s advance. But the very characteristics that make chemotherapy effective against cancer also can make it toxic to healthy cells, leading to side effects such as hair loss, nausea, ...
  • When you want to understand how to enhance the patient experience, go straight to the source: The patients. Patients and their families offer unique perspectives on care and services and can provide valuable insights about what is working well and what is not. That’s why City of Hope turns to them for advice. S...
  • Take it from City of Hope researchers: Medical science isn’t just for scientists, but something the whole family can enjoy. From 1 to 4 p.m. on Saturday, May 16, the institution will offer a variety of educational and fun-filled science and healthy living activities at its second Community Science Festiva...
  • Attention, parents! Only a few serious sunburns can increase a child’s ultimate risk of skin cancer. Further, some studies suggest that ultraviolet (UV) exposure before the age of 10 is the most important factor for melanoma risk. Here skin cancer expert Jae Jung, M.D., Ph.D., assistant professor in the D...
  • Esophagheal cancer may not be on many people’s radar, but heartburn probably is. The latter can ultimately lead to the former. More formally referred to as gastroesophageal reflux, heartburn occurs when stomach content makes its way back up into the esophagus, causing stomach acid to come into contact with the ...
  • Many City of Hope cancer patients are opening their hearts to an electronic confidante. The tablet-based program, called SupportScreen, prompts them to share deeply personal concerns about their health — and helps jump-start their care. “We’ve found that people will reveal more to a machine than to a person. Te...
  • Older adults, by far, represent the largest population of cancer patients globally. With the median age of U.S. citizens projected to increase sharply in the next few years, the incidence of cancer is expected to rise higher, as well. City of Hope is at the forefront of geriatric cancer care, and an important n...
  • Treatment of cancers of the head and neck requires not just skill, but consummate skill. After all, consider their location: the lip, mouth, tongue, throat and nasal cavity – and that’s just for starters. Such treatment can include chemotherapy and radiation, but surgery is often the primary approach, wit...
  • On a spring day in 2013, 10-year-old Jackie Garcia of Whittier, California, noticed a lump in her jaw. Her mother suspected it was a minor problem, perhaps due to a fall, but made an appointment with a pediatrician, just to be on the safe side. “He thought it was an infection that was dental-related, and told [...
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