An NCI-designated Comprehensive Cancer Center

Judith Singer-Sam, Ph.D.

Professor Emeritus, Diabetes & Metabolism Research Institute
Research Focus
  • Epigenetics
  • Mono-allelic Expression
  • Central Nervous System
Other Languages Spoken
  • French


City of Hope Comprehensive Cancer Center, 1500 East Duarte Road

Duarte, CA 91010

  • Li, M., Valo, Z., Wang, J., Gao, H., Bowers, C.W., Singer-Sam, J. (2012). Transcriptome-wide survey of     mouse CNS-derived cells reveals monoallelic expression within novel gene families.  PLoS ONE  7,     e31751.
  • Wang, J., Valo, Z., Bowers, C., Smith, D., Liu, Z, Singer-Sam, J. (2010). Dual DNA methylation patterns in     the CNS reveal developmentally poised chromatin and monoallelic expression of critical genes.  PLoS     ONE  5, e13843.
  • Singer-Sam, J. (2010).  Monoallelic expression. Nature Education 3, 1.
  • Wang, J., Valo, Z., Smith, D., and Singer-Sam, J. (2007). Monoallelic expression of multiple genes in the CNS. PLoS ONE 2, e1293.
  • Bowers, C.H. and Singer-Sam, J. (2007).  Unique retrotransposon LINE-1 distribution at the Prader-    Willi/Angelman syndrome locus. J. Mol. Evol. 65, 475-484.
  • Buettner, V. L., Walker, A. L., and Singer-Sam, J. (2005). Novel paternally expressed intergenic transcripts  at the mouse Prader-Willi/Angelman Syndrome locus. Mammalian Genome 16, 219-227
  • Buettner, V. L., Longmate, J. A., Barish, M. E., Mann, J. R., and Singer-Sam, J. (2004). Analysis of imprinting in mice with uniparental duplication of proximal chromosomes 7 and 15 by use of a custom oligonucleotide microarray. Mammalian Genome 15, 199-209.
  • Shively, L., Chang, L., LeBon, J. M., Liu, Q., Riggs, A. D., and Singer-Sam, J. (2003). A real time PCR assay for quantitative mismatch detection. BioTechniques 34, 498-504.
  • Ring, R. H., Valo, Z., Gao, C., Barish, M. E., and Singer-Sam, J. (2003). The Cdkn1a gene (p21WAf1/Cip1) is an inflammatory response gene in the mouse central nervous system. Neurosci. Lett. 350, 73-76.
  • Singer-Sam, J., and Gao, C. (2001). Quantitative RT-PCR-based analysis of allele-specific gene expression. In Methods in Molecular Biology, A. Ward, ed. (Totowa, NJ, Humana Press), pp. 145-152.
  • Mann, J. R., Szabo, P. E., Reed, M. R., and Singer-Sam, J. (2000). Methylated DNA sequences in genomic imprinting. In Critical Reviews in Eukaryotic Gene Expression, G. S. Stein, J. L. Stein, and J. B. Lian, eds. (New York, Begell House, Inc.), pp. 241-257.
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