Top Cancer Treatment and Research Center | City of Hope

City of Hope^®, one of the largest and most advanced cancer research and treatment organizations in the United States, has been recognized as having one of the nation’s Top 5 hospitals for cancer care, according to U.S. News & World Report’s 2024-25 rankings. The recognition marks the latest milestone for City of Hope as it enhances its ability to make a meaningful impact in the lives of patients, families and communities nationwide.

We are bringing breakthroughs from the laboratory to our patients, with lifesaving speed – treating cancer with leading-edge technologies, innovative treatments and supportive care tailored to each patient’s needs.

And we’re treating patients across the United States through our national footprint of cancer centers.

Learn about our cancer centers by exploring the links below.

Our Cancer Centers

Atlanta Area

City of Hope Chicago

Chicago Area

Los Angeles Area

NCI-Designated Comprehensive Cancer Center

Orange County Area

City of Hope Phoenix Cancer Center building

Phoenix Area

Stephenson Prize Innovations in Pancreatice Cancer Reasearch.

A Transformative Gift From the Stephenson Family

City of Hope has received a historic $150 million gift from entrepreneur and philanthropist A. Emmet Stephenson Jr. and his daughter Tessa Stephenson Brand to immediately fund pancreatic cancer research.

Learn more about this transformative gift

NCI's Top Designation for Cancer Centers

Our National Cancer Center near Los Angeles is a National Cancer Institute (NCI)-Designated Comprehensive Cancer Center. This designation recognizes City of Hope as a national leader in cancer care and an institute dedicated to transforming research into new, innovative treatments for cancer patients across the country and world.

NCI Designated Comprensive Cancer Center

Patient-Focused Care

Our reputation for groundbreaking discoveries, innovative treatments and compassionate care make us a leader in the fight to help patients here and around the world conquer cancer, diabetes, HIV/AIDS and other life-threatening diseases.

A group of City of Hope doctors providing patient care together

Cancers and Conditions We Treat

Refer a Patient to City of Hope

Forward-Focused Research

Our infrastructure and collaborative energy sets us apart. By having scientists, treatment staff and manufacturing facilities side-by-side, our treatment advances can travel from laboratory to patient with lifesaving speed.

A technician working in a lab

Explore Our Research

Search Clinical Trials

Read Latest News

Hope-Inspired Learning

As a leading research institute, our academic programs look beyond the standard treatments of today, providing educational opportunities that explore the latest advancements in research and therapies.

Graduation ceremony at the Beckman Research Institute

Explore Academics & Training

Irell & Manella Graduate School

FIND A CITY OF HOPE DOCTOR

City of Hope is home to many of the nation's leading cancer doctors. Find the right one for your patient’s needs.

FIND A CITY OF HOPE LOCATION

Headquartered in Duarte, California, with locations across the United States, our unique approach to care is available in your community.

HOW TO REFER A PATIENT

We're here to help and welcome the opportunity to partner with you in providing your patients with the latest treatment innovations.

PHYSICIAN CAREERS

Join a world leader in treating, researching and preventing life-threatening diseases, including cancer, diabetes and HIV/AIDS.

News and City Stories

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City of Hope Orange County leads “Pink is Powerful” breast health initiative

City of Hope Orange County

City of Hope Orange County leads “Pink is Powerful” breast health initiative

Pink lab coats symbolize shared commitment to educate women about the importance of mammograms and raise awareness of the impact of breast cancer in Orange County.

Ashley Saylor artwork

Young Mom Perseveres Over Stage 3 Breast Cancer

Months after giving birth to her first child, Ashley Saylor was diagnosed with triple-negative breast cancer. Her City of Hope care team and the power of art saw her through treatment challenges

Grateful ovarian cancer patient is back on the road to tomorrow

City of Hope Orange County

Grateful ovarian cancer patient is back on the road to tomorrow

Cancer demanded Viana Mehl-Laituri’s full attention right after she finished grad school. She reset her life “back to normal” through City of Hope Orange County’s advanced expertise in gynecologic oncology.

Give Hope

You can accelerate leading-edge research and help provide compassionate patient-care.