
Together We Deliver Hope
Choose Hope for Your Patients
Our comprehensive programs offer a wide variety of services — from precision medicine and medical oncology to surgical oncology and infusion therapies — bringing world-renowned care to your patients.
City of Hope’s breast cancer physician scientists are highly specialized experts focusing on one type of disease, bringing the latest treatments from the laboratory to bedside with lifesaving speed. Our top-ranked breast cancer physicians dedicate themselves to help care for patients through prevention, diagnosis, treatment, access to clinical trials, and transition to recovery.
City of hope surpasses SEER national median survival for female breast Cancer survival rates at all stages (Stages I–IV). Our Stage IV survival is 50% Greater than the seer national average of 10 years post-diagnosis.
Our specialized surgical team brings patients the latest techniques for treating breast cancer, including minimally invasive approaches, breast-conserving surgery and reconstructive surgery. Surgical treatment options include, but are not limited to:
- One-stage implant reconstruction
- Autologous reconstruction
- Concurrent oncoplastic surgery
- Nerve preservation
- Nipple and skin-sparing mastectomy
- Axillary reverse mapping
- Lymphovenous bypass
- Aesthetic flat closure
City of Hope’s approach to treating gastrointestinal cancers starts with a coordinated, multidisciplinary care team whose main goals are helping patients live a long, healthy, cancer-free life. We combine leading-edge technologies — like minimally invasive laparoscopic and robotic surgeries — with the latest precision medicine, therapeutic and radiological advances.
Specializing in GI Cancers and Conditions
- Anal cancer
- Appendix cancer
- Bile duct cancer
- Biliary tract cancers (BTC)
- Cancer of unknown primary (CUP)
- Cholangiocarcinoma
- Colon cancer
- Colorectal cancer
- Esophageal cancer
- Hepatobiliary Cancers
- Hepatocellular Cancer (HCC)
- Hereditary colorectal cancer syndromes including familial adenomatous polyposis (FAP) and Lynch syndrome (hereditary non-polyposis colorectal cancer)
- Liver cancer
- Neuroendocrine tumor (NET)
- Pancreatic cancer
- Rectal cancer
- Stomach cancer
For a complete list of treatment options and team members, click the learn more button below.
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City of Hope has developed Orange County’s most integrated program for gynecologic oncology and urogynecologic care. This unique program offers your patients a broad range of expertise in cancer treatment, complex non-cancerous gynecologic disorders, urogynecology and pelvic floor dysfunction.
Our nationally recognized oncologists, radiation oncologists, interventionalists, supportive medicine specialists and surgical teams are all highly regarded for their innovation and utilization of the most advanced treatment techniques.
Specializing In Gynecologic Oncology Cancers and Conditions
- Gynecologic pre-cancer prevention
- Ovarian cancer (ovaries, fallopian tubes, etc.)
- Uterine cancer (uterus, endometrium, etc.)
- Cervical cancer (neoplasms of the cervix, vulva, etc.)
- Vaginal cancer, vulvar cancer
- Genetic predispositions (BRCA1, BRCA2, Lynch syndrome)
- Strong family history of cancer (ovarian, uterine and breast)
- Advanced endometriosis
- DES exposure in utero
- Cervical stenosis
- Pelvic and ovarian masses
- Cervical, vaginal and vulvar dysplasia
Specializing In Urogynecology Conditions
- Pelvic floor disorders
- Urinary incontinence
- Fecal incontinence
- Pelvic organ prolapse
- Recurrent UTI
- Urethral diverticulum
- Hematuria
- Vaginal stenosis
- Pelvic pain, interstitial cystitis
- Vesicovaginal and rectovaginal fistulas
- Overactive bladder syndrome
- Congenital anomalies of the genitourinary tract
- Neurogenic bladder
- Post-delivery pelvic floor dysfunction
- Vaginal atrophy
For a complete list of treatment options and team members, click the learn more button below.
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As a pioneer in advancing care for all hematologic cancers and related blood disorders, City of Hope leads the field as one of the largest and most successful hematology centers in the United States. Our dedicated, multidisciplinary team combines innovative research discoveries with superior clinical treatments to improve outcomes for patients with the most common to incredibly rare hematologic diseases, including leukemia, lymphoma, myeloma, amyloidosis, myelodysplastic syndrome, and other benign hematologic disorders.
Sub-Specializing In Simple And Complex Hematology
- Leukemia
- Complex lymphoma (including Hodgkin lymphoma)
- B-cell non-Hodgkin lymphomas
- DLBCL
- Mantle cell lymphoma
- Follicular lymphoma
- CLL/SLL
- Waldenstrom’s macroglobulinemia
- Marginal zone lymphoma
- Complex multiple myeloma
- Non-malignant hematology
- Myelodysplastic syndrome
- Myeloproliferative neoplasms
- Hematopoietic cell transplantation (HCT)
- Chimeric antigen receptor T-cell therapy (CART)
For more information on how City of Hope Orange County is pioneering hematology treatments and to see a complete list of team members, click the learn more button below.
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City of Hope is a nationally recognized leader in the research and treatment of lung cancer, one of the most common cancers in the United States and a leading cause of cancer deaths worldwide. We combine acclaimed lung cancer expertise, leading-edge technologies and advanced therapies with access to pioneering research and lifesaving clinical trials to offer you and your patients the most advanced comprehensive lung cancer care in the region.
For more information and a complete list of team members, click the learn more button below.
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City of Hope offers the most innovative treatments and internationally recognized physician scientists. When treating a genitourinary cancer diagnosis, our dedicated team of experts takes a uniquely integrated, patient-centered approach to diagnose and treat the prostate, kidney, bladder, testicular and penile cancer to ensure optimal outcomes with minimal impact on quality of life. Our surgical specialists have performed over 5,000 procedures.
Fellowship-trained program leaders bring an extra level of education and specialization to genitourinary cancer care. Our specialists use research and technology to treat some of the most complex genitourinary conditions not treated at other facilities.
For a complete list of treatment options and team members, click the learn more button below.
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City of Hope Orange County Lennar Foundation Cancer Center’s Department of Radiation Oncology is leading the way in improving patient care with the latest radiation treatments. With TrueBeam®, Ethos® and MRIdian®, we offer the most comprehensive, specialized radiation oncology programs in Orange County and one of the most advanced in the country.
As Southern California’s only Center of Excellence for Adaptive Radiotherapy (ART), City of Hope excels at techniques that direct radiation precisely to the tumor, minimizing healthy organ exposure, which results in improved outcomes and shorter treatments.
For more information on our advanced technologies, treatment capabilities and to see a complete list of team members, click the learn more button below.
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We’re well-trained to care for patients with allergy and immunology, bone health (Osteoporosis), cardiology, dermatology, gastroenterology, infectious disease, neurology, ophthalmology, rheumatology, transplant, and many other conditions.
Here’s a listing of many conditions we treat:
- Amyotrophic Lateral Sclerosis (ALS)
- Alzheimer’s
- Anemia
- Asthma
- Fabry Disease
- Gout
- Hypercholesterolemia
- Hunter Syndrome
- Immunotherapy
- Inflammatory Bowel Disease
- Kidney Transplant
- Lupus
- Migraines
- Multiple Cancers
- Multiple Sclerosis
- Osteoporosis
- Polyneuropathy
- Psoriasis
- Rheumatoid Arthritis
- Sarcoid Myocarditis
- Thyroid Eye Disease
For more information on our non-oncology infusion services, medications offered, locations and how to refer a patient, click the learn more button below.
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City of Hope Orange County brings specialized cancer care and clinical trials closer to home. Easily scroll through our specialties to find a physician at Lennar Foundation Cancer Center or one of our regional network locations.

Your direct contact to help navigate the referral process.
- Answers for service offerings, locations and how to access our cancer experts.
- Help with patient intake, scheduling and post-appointment follow-up.

We work in partnership with you and your patients. Three ways to refer a patient.
- Call centralized referral at 866-408-1263.
- Download referral form and fax to 949-777-6750.
- Contact one of our regional clinics directly.
You may also connect with a physician liaison to help navigate the referral process.

Additional Referral Resources
City of Hope provides innovative and groundbreaking techniques for the treatment of cancer. Refer your patient today.
We're here to help and welcome the opportunity to partner with you in providing your patients with the latest treatment innovations.
City of Hope Orange County Lennar Foundation Cancer Center Breast Screening & Diagnostic Center Referring Physician Order Form.
City of Hope Orange County's expertise in infusion therapy extends beyond cancer-related drugs. We also administer non-oncology medications.
For more information about our comprehensive cancer program, or to schedule a one-on-one with a City of Hope cancer expert, please contact one of our physician liaisons.
City of Hope Orange County Lennar Foundation Cancer Center supports general x-ray, fluoroscopy, ultrasound, CT, MRI, molecular/nuclear medicine, and interventional radiology service request.
"City of Hope is in Orange County to provide world-renowned research, pioneering therapies, and nationally-recognized compassionate care for patients with common or complex cancers. Our focus is on the future of cancer care and providing the best chance for cancer survival."
— Edward Kim M.D., M.B.A., Physician-in-Chief at City of Hope Orange County and nationally recognized advocate for expanding access to lifesaving clinical trialse

Orange County Regional Network Locations
Find expert and compassionate care through our City of Hope network, including City of Hope Orange County Lennar Foundation Cancer Center and five network locations in Sand Canyon, Newport Beach, Huntington Beach, and Long Beach.
City of Hope National Medical Center
Hospital-Based Outpatient Facilities
TAX ID: 95-1683875 | SITE NPI#: 1750358297
1000 FivePoint, Irvine, CA 92618
Phone: 866-408-1263 | Fax: 949-777-6750
2100 Main St., Ste. 300, Huntington Beach, CA 92648
Phone: 866-408-1263 | Fax: 714-963-8407
Regional Network Clinics
TAX ID: 27-4803222 | SITE NPI#: 1871886366
1601 Avocado Ave., Newport Beach, CA 92660
Phone: 949-763-2204 | Fax: 949-536-8036
16300 Sand Canyon Ave., Ste. 207, Irvine, CA 92618
Phone: 949-333-7580 | Fax: 949-333-7599
1043 Elm Ave., Ste. 104, Long Beach, CA 90813
Phone: 562-590-0345 | Fax: 562-437-8139
3747 Worsham Ave., Ste. 101, Long Beach, CA 90808
Phone: 562-430-5900 | Fax: 562-799-8379