Hematologic Services
Conditions and Treatments
City of Hope offers the most innovative treatments and internationally recognized physician scientists. Our cancer center and hospital teams are specially trained and experienced in treating cancer, which provides additional expertise in specialized post-op care.
- Leukemia
- Acute lymphoblastic leukemia
- Acute myeloid leukemia (AML)
- Chronic myelogenous leukemia
- Lymphoma
- Hodgkin lymphoma
- B-cell non-Hodgkin lymphomas including:
- Chronic lymphocytic leukemia (CLL)
- Diffuse large B-cell lymphoma
- Follicular lymphoma
- Hairy cell leukemia (HCL)
- Lymphoplasmacytic lymphoma
- Mantle cell lymphoma
- Marginal zone lymphoma
- Small lymphocytic lymphoma (SLL)
- Waldenstrom’s macroglobulinemia
- Myelodysplastic syndrome
- Myeloma and complex plasma cell disorders including:
- Amyloidosis
- Monoclonal gammopathy of renal significance (MGRS)
- Monoclonal gammopathy of undetermined significance (MGUS)
- POEMS syndrome
- Smoldering Myeloma
- Myeloma and complex plasma cell disorders including:
- Myeloproliferative neoplasms
- Allogeneic and autologous (BMT)
- Bispecific antibody therapy
- CAR T-cell therapy
- Gene therapy
- Hematopoietic cell transplantation (HCT)
- Immunotherapy
- Novel targeted therapies
- Oral and systemic chemotherapy
- Post transplant services
- Radiation therapy
- Supportive care services
Why Choose City of Hope
Driving the Field Forward — An International Pioneer
for Hematology Treatments
City of Hope Orange County physician scientists lead the development of a large, diverse clinical trial portfolio for leukemia, multiple myeloma and lymphoma including newly diagnosed patients as well as those with more advanced disease.
Over 81 ongoing clinical trials in Orange County, the most in the region, advancing new therapies specifically for hematologic cancers.
City of Hope is one of the largest and most successful bone marrow and blood stem cell transplant centers in the world. It’s ranked as “overperforming” by the Center for International Blood and Marrow Transplant Research (CIBMTR)
Instrumental in developing new bispecific antibody therapies in lymphoma and multiple myeloma.
Now providing CAR T cell therapy in the outpatient setting.
Nearly 20,000 bone marrow transplants across City of Hope’s national network.
Unique Power of City of Hope
Here we expand and broaden our world-renowned work in the research and treatment of all forms of leukemia, with a particular emphasis on acute myeloid leukemia, a major cause of death in older patients.
The center has earned its third Lymphoma Specialized Programs of Research Institute (SPORE) grant from the National Cancer Institute. City of Hope holds one of the two mantle cell lymphoma Specialized Center of Research awards in the United States.
Our goal is to improve the overall quality of life for survivors of hematologic cancers beyond treatment through one of the largest cohorts (more than 11,000) of long-term survivors in active follow-up.
The mission of this team is to reduce treatment toxicity and improve patient outcomes by using leading-edge research to advance hematopoietic stem cell transplant methods.
One of the most comprehensive CAR T cell therapy programs globally. With CAR T cell engineering and manufacturing, we are one of only a handful of centers in the country applying proprietary CAR T technology in active preclinical and clinical programs.
A world-class leader in research on genetic modification of stem cells, we’re dedicated to converting that research into real-world treatments and cures as quickly as possible.
City of Hope has played a role in nearly every modern treatment for myeloma and the only Southern California member of the Multiple Myeloma Research Foundation. We are pioneers in bispecific and trispecific antibody treatments, novel CART therapies and rapid whole genome sequencing to better tailor promising new treatments to patients.
We work in partnership with you and your patients. Three ways to refer a patient.
- Call centralized referral at 866-408-1263.
- Download referral form and fax to 949-777-6750.
- Contact one of our regional clinics directly.
You may also connect with a physician liaison to help navigate the referral process.
Additional Referral Resources
We're here to help and welcome the opportunity to partner with you in providing your patients with the latest treatment innovations.
City of Hope Orange County's expertise in infusion therapy extends beyond cancer-related drugs. We also administer non-oncology medications.
City of Hope Orange County Lennar Foundation Cancer Center supports general x-ray, fluoroscopy, ultrasound, CT, MRI, molecular/nuclear medicine, and interventional radiology service request.
Our Hematology Experts
Internationally renowned hematologic cancer experts right here in Orange County. With a focus on targeted treatments and clinical trials, our physician scientists for hematology are also industry leaders in dramatically improving the lives of patients with amyloidosis, Hodgkin’s disease, leukemia, lymphoma, multiple myeloma, myelodysplastic syndrome and more.
Profile Key:
- LFCC — City of Hope Orange County Lennar Foundation Cancer Center
- LBE — Long Beach Elm
- LBW — Long Beach Worsham
- NB — Newport Beach
- SC — Sand Canyon
- S — Seacliff
- Blue play button — Will play BIO video in existing window
- Full bio button — Will exit page and open full BIO
Complex Multiple Myeloma, Multiple Myeloma, Smoldering Myeloma, hematopoietic cell transplantation HCT, and CAR T-cell therapy.
Executive Medical Director, Hematology & Hematopoietic Cell Transplantation | Complex Multiple Myeloma, HCT & CAR T
LFCC | NB
Hematologist
LFCC | S
Complex lymphoma including Hodgkin lymphoma and all types of B-cell non-Hodgkin lymphomas (eg. DLBCL, mantle cell lymphoma, follicular lymphoma, CLL/SLL, Waldenstrom’s macroglobulinemia, marginal zone lymphoma, hairy cell leukemia), hematopoietic cell transplantation HCT, and CAR T-cell therapy.
Medical Director of Lymphoma | Director, Chronic Lymphocytic Leukemia (CLL) Program | Lymphoma, Leukemia, HCT & CAR T
LFCC
Complex Lymphoma, Non‑Malignant Hematology, Myelodysplastic Syndrome & Myeloproliferative Neoplasms, HCT & CAR T
LFCC
Hematologist
LFCC
Acute Leukemias, Chronic Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Hematopoietic Cell Transplantation (HCT), Essential Thrombocythemia, Myelofibrosis, Myeloproliferative Neoplasms, Polycythemia Vera, and CAR T-cell therapy.
Hematologist-Oncologist Section Leader | Myeloproliferative Neoplasms (MPH) Program Leukemia & Cell Transplantations
Duarte M.D. at LFCC
Julio Cesar Alvarenga, M.D., is Assistant Clinical Professor at City of Hope Orange County Lennar Foundation Cancer Center.
Hematology & Hematopoietic Cell Transplantation | Leukemia and Acute Leukemia
LFCC
Medical Director, Integrative Medicine & Supportive Care | GI Medical Oncology
LFCC
Physiatrist | Physical Medicine
and Rehabilitation
LFCC | SC
Interventional Pain Management
LFCC | S
Your direct contact to help navigate the referral process.
- Answers for service offerings, locations and how to access our cancer experts.
- Help with patient intake, scheduling and post-appointment follow-up.
Orange County Regional
Network Locations
Find expert and compassionate care through our City of Hope network, including City of Hope Orange County's Cancer Specialty Hospital, Lennar Foundation Cancer Center and five network locations in Sand Canyon, Newport Beach, Huntington Beach, and Long Beach.
City of Hope National Medical Center Provider-Based Locations
TAX ID: 95-1683875 | SITE NPI#: 1750358297
Cancer Specialty Hospital
Lennar Foundation Cancer Center
1000 FivePoint, Irvine, CA 92618
Phone: 866-408-1263 | Fax: 949-777-6750
2100 Main St., Ste. 300, Huntington Beach, CA 92648
Phone: 866-408-1263 | Fax: 714-963-8407
Regional Network Clinics
TAX ID: 27-4803222 | SITE NPI#: 1871886366
1601 Avocado Ave., Newport Beach, CA 92660
Phone: 949-873-0726 | Fax: 949-536-8036
16300 Sand Canyon Ave., Ste. 207, Irvine, CA 92618
Phone: 949-333-7580 | Fax: 949-333-7599
1043 Elm Ave., Ste. 104, Long Beach, CA 90813
Phone: 562-590-0345 | Fax: 562-437-8139
3747 Worsham Ave., Ste. 101, Long Beach, CA 90808
Phone: 562-430-5900 | Fax: 562-799-8379