An NCI-designated Comprehensive Cancer Center


Pediatric Nurse Wearing PPE

Our COVID-19 Measures

We're taking preventive measures to protect our patients, caregivers and staff as the COVID-19 situation evolves, including a strict visitor policy and requirement to wear a mask at all times.
These heightened restrictions are based on the latest information and recommendations from public health authorities during this critical period and will remain in effect until further notice.
Please visit our Visitor Policy page for more detail.
Patient Hotline: Call 844-961-4673 for general questions about COVID-19 between 9 a.m. to 5 p.m., Monday to Friday

Cancer Doesn't Stop

To find out more about our services or schedule an appointment at City of Hope Newport Beach, call 949-763-2204.

City of Hope knows our patients need us more than ever. We’re providing lifesaving treatments from our location in Newport Beach, California, while doing everything we can to keep you safe.  Find the latest in personalized therapies, highly specialized physicians and nationally recognized compassionate care at 1601 Avocado Avenue.


Meet the science that's fighting cancer

"Each cancer is unique, which is why we assembled a roster of outstanding researchers and physicians who provide targeted treatments for specific cancer diagnoses." - Ravi Salgia, M.D., Ph.D.
City of Hope | Newport Beach is home to many of the nation’s leading clinician-scientists who are transforming laboratory breakthroughs into treatments to offer the best hope for patients. Due to their expertise in caring for immunocompromised patients, they are among the most prepared providers in the country to help cancer patients through this COVID-19 crisis.

A campus of the future

Orange County City of Hope Irvine Campus
Last year, City of Hope announced a plan to invest $1 billion to develop and operate a 21st century comprehensive cancer campus in Irvine and a network of care that will provide residents unprecedented access to leading-edge medicine. City of Hope leaders and volunteers are engaging the philanthropic community to help make this vision a reality.
Our comprehensive cancer campus at Irvine’s FivePoint Gateway is being developed in partnership with FivePoint, an owner and developer of large mixed-use, master-planned communities in California.
The cancer campus will bring highly specialized care, clinical trials, precision medicine, and early detection closer to home. Housed on 11 acres, it will include Orange County’s only specialty hospital exclusively focused on treating and curing cancer, which will open in 2025.
The World Class Campus will include:
  • An outpatient center offering diagnostic imaging and screenings, precision medicine and early detection, medical oncology, and much more
  • A clinical research center offering phase I-III clinical trials
  • Personalized supportive care services, upheld as a model for other institutions across the country, to address physical and emotional issues that can arise during treatment 
  • Access to a wide range of solid tumor and blood cancer specialists dedicated to finding the best treatments for each patient

Now Open in Newport Beach

Newport Beach Location
City of Hope Newport Beach, our first location in Orange County, brings the latest in personalized therapies, highly specialized physicians and nationally recognized compassionate care to local communities. 
Using our expertise in numerous diseases with a focus on breast cancer, colorectal cancer, lung and thoracic cancers, urology, urologic cancers, gastrointestinal and genitourinary cancers, hematology and hematologic cancers, as well as an array of world-class technologies and services, City of Hope cares for patients from prevention through survivorship.
Services offered include: medical oncology, hematology and hematology-oncology, surgery and surgery-oncology, chemotheraphy/infusion therapy, precision prevention and early detection, and supportive care.

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If you are a reporter and want to learn more about City of Hope Orange County, contact Nisha Morris at [email protected].

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