Newport Beach

City of Hope | Newport Beach brings the latest in personalized cancer therapies, highly specialized physicians and nationally recognized compassionate care to local communities.

Designed with the patient in mind, City of Hope Newport Beach houses a state-of-the-art infusion center with serene ocean views and comfortable treatment bays, a patient resource center, light and bright exam rooms equipped with large-screen monitors, and two procedure rooms for multiple minor surgical procedures and biopsies. Physicians and staff offer another City of Hope hallmark - compassionate care throughout the cancer journey for patients and their families.

33.6148476, -117.8689171

1601 Avocado Avenue
Newport Beach, CA 92660
All Patients
Hope Infusions

Monday through Friday
8:00 a.m. - 6:30 p.m.
Closed on major federal holidays


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City of Hope cares for patients from prevention through survivorship by pairing our expertise in numerous cancers and conditions with world-class technologies and services.

Recognizing that many types of cancer require specialists with highly focused knowledge, City of Hope Newport Beach offers a roster of physicians who possess unique cancer expertise. The specialty team includes an internationally recognized researcher in multiple myeloma treatment, a pioneer in kidney and bladder cancer, one of the country’s leading experts and researchers on colorectal cancer, a surgeon focusing exclusively on breast surgery and aesthetic reconstruction, and a national thought leader in cancer patient education and prevention.

City of Hope Newport Beach also offers an innovative Precision Prevention and Early Detection Program designed to inform individuals and families of their risk factors based on state-of-the-art technologies.

The infusion center provides relaxing views of the Pacific Ocean, green landscapes and California sunlight. Designed with warm natural wood and organic stone accents, the center features 17 outward-facing patient bays (two are semi-private), heated blankets, cozy soft loungers, dimming lights, complimentary beverages and snacks, free Wi-Fi, and the use of iPads and headphones to ensure patient comfort. Chemotherapy, immunotherapy, intraperitoneal chemotherapy, hydration, IVIG, IV Iron and IV antibiotics are all available in the center.

Our medical oncology program includes the diagnosis and treatment of benign and malignant tumors, as well as a variety of blood disorders. Patients have access to the latest advances in chemotherapy, immunotherapy, and pain and symptom management, including hormonal, biologic and targeted therapies to ensure optimal outcomes across a broad spectrum of diagnoses.


For the first time, Orange County residents have local access to City of Hope’s world-renowned physicians, who are backed by the powerful City of Hope clinical network.

Is My Insurance Accepted?

View a list of insurance companies that City of Hope currently contracts with for its locations and physicians. Even if your plan is included, check with your insurance company to make sure you are covered. Your insurance company/medical group will tell you if you need any authorizations.

If you wish to receive treatment at City of Hope, but we're not currently contracted with your insurance plan, contact your insurance company and ask about obtaining authorization to receive treatment here.

View our pricing and billing

Provider based billing

No Surprise Billing

When you're treated by an out-of-network provider at an in-network facility, you are protected from balance billing. In these cases, you shouldn't be charged more than your plan's copayments, coinsurance and/or deductible. Learn about your rights and protections against surprise medical bills

Hope Infusions

City of Hope’s expertise in infusion therapy extends beyond cancer-related drugs. We are uniquely equipped to offer non-oncology infusion options safely and effectively, supported by our patient-centered approach to care. Contact our Hope Infusions patient concierge team to learn how we verify insurance coverage before your first appointment: 949-671-4146.

Explore City of Hope Newport Beach

City of Hope opened a new chapter in Newport Beach. This site is more than our first location in Orange County. It's where our story of new hope and promise begins. We're providing never-before-available cancer breakthroughs, delivered by world-renowned clinician-scientists with unique cancer expertise. 

Newport Beach Building Exterior
Newport Beach 1 year
Newport Beach Building Infusion Center
Newport Beach Building Interior

Visiting City of Hope Orange County Newport Beach?

Our Physicians

Monzr M. Al Malki, M.D.
Monzr M. Al Malki, M.D.

Monzr M. Al Malki, M.D., is an associate professor in the Department of Hematology & Hematopoietic Cell Transplantation and is board certified in internal medicine, hematology and medical oncology at City of Hope.

Meet Dr. Seth A. Cohen
Seth A. Cohen, M.D.
Urologic Surgeon; Urogynecologist

Seth Cohen, M.D., is a urologic surgeon with a focus on female pelvic medicine and reconstructive surgery at City of Hope's community practice sites in Orange County.

Joshua G. Cohen, M.D., F.A.C.O.G., F.A.C.S., is a board-certified gynecologic oncologist dedicated to offering his patients in Orange County empathy and excellence in clinical care.

Doctor Misagh Karimi
Misagh Karimi, M.D.
Medical Oncologist and Hematologist

Misagh Karimi, M.D., is a medical oncologist who is passionate about patient education, appearing frequently at community forums to discuss obesity, the environment and other possible risk factors for cancer.

Amrita Krishnan, M.D.

Amrita Krishnan, M.D., directs the Judy and Bernard Briskin Center for Multiple Myeloma Research at City of Hope's cancer research hospital, seeking to make gains in one of the most rapidly changing areas in cancer research.

Christian C. Lu, M.D., M.H.S.
Christian C. Lu, M.D., M.H.S.
Assistant Clinical Professor

Christian Co Lu, M.D., M.H.S., is a patient-centric physician with 15+ years of experience in medical care. 

Hoda Pourhassan, M.D
Hoda Pourhassan, M.D.

Hoda Pourhassan, M.D., is a hematologist-oncologist in the Department of Hematology & Hematopoietic Cell Transplantation at City of Hope.

George Semeniuk III, M.D.
George Bernard Semeniuk, III, M.D.
Medical Oncologist and Hematologist

George Bernard Semeniuk, III, M.D., is a hematologist/oncologist specializing in leukemia, lymphoma and hematopoietic cell transplantation.

Wade Smith, M.D.
Wade Smith, M.D.
Medical Oncologist and Hematologist

Wade Smith, M.D., is a medical oncologist specializing in breast cancer at City of Hope Orange County and Duarte.

Dr.Tin Tang  profile image
Tingting Tan, M.D., Ph.D.
Medical Oncologist and Hematologist

Tingting Tan, M.D., Ph.D., is a medical oncologist and assistant clinical professor in the Department of Medical Oncology & Therapeutics Research at City of Hope.

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