With the opening of the City of Hope’s Cancer Specialty Hospital on its 72-acre academic research campus, City of Hope advances a next-generation national model of cancer care for the more than 2 million Americans diagnosed each year. Patients benefit from access to a complete continuum of advanced cancer care—from prevention through survivorship—delivered on a single academic cancer campus built for the single purpose of saving lives.
City of Hope Orange County Cancer Specialty Hospital is a provider-based facility of City of Hope National Medical Center, a general acute care hospital. Together, they complete the region’s most advanced and fully integrated cancer care network, expanding access to specialized expertise, innovative acute and outpatient treatments, novel clinical trials, and groundbreaking technologies. Seamlessly connected to the Lennar Foundation Cancer Center, the hospital was intentionally designed with and for the community it serves.
33.6518172, -117.7313691
Irvine, CA 92618
Monday - Sunday: 24/7 patient care
Open on federal holidays
- Clinical Services
- Planning a Trip
- Insurance Information
City of Hope is an internationally recognized leader in cancer research and specialized care, noted for driving advancements in CAR T and advanced cellular therapies, a national network of hundreds of clinical trials, unique supportive care and survivorship programs, and renowned experts across cancer sub-specialties.
- Highly Specialized Cancer-Focused Expertise
The academic research campus is now home to more than 100 world-renowned surgical oncologists, medical oncologists and hematologists with specialized expertise in treating thoracic, gastrointestinal cancers, women’s cancers, urologic cancers, plastic surgery and more as well as pulmonologists and hospitalists. - Clinical Trials
City of Hope patients currently have access to more than 700 Phase 1-3 clinical trials conducted each year, the most cancer-focused clinical trials in Southern California. The new hospital provides access to 30 percent more cancer-focused clinical trials, including early-stage clinical trials in hematology and solid tumors. These Phase 1 clinical trials require close supervision in a hospital setting.
For Patients and Visitors
Family and friends are always welcome and encouraged to visit patients during their stay at City of Hope.
Find out what you need to know about patient and family services available at our Irvine Academic Research Campus.
Primary visitors typically the patient’s closest family or friends – will receive wristbands for visitation during operational hours: 6:00 am to 9:00 pm. Please note that for the patient's health, safety and well-being, staff may request visitors to leave the patient room and wait in the visitor lounges located near the elevators on each floor of the hospital. Click here to view additional visitor information.
Download the Irvine Academic Research campus map >
Upcoming Appointments
If you have an upcoming appointment at City of Hope Orange County cancer specialty hospital, the MyCityofHope app makes the check-in process fast and simple. Our Preparing for Your Hospital Stay page includes steps on what to know about your visit, what to bring with you to your appointment and other resources.
Is My Insurance Accepted?
View a list of insurance companies that City of Hope currently contracts with for its locations and physicians. Even if your plan is included, check with your insurance company to make sure you are covered. Your insurance company/medical group will tell you if you need any authorizations.
If you wish to receive treatment at City of Hope, but we're not currently contracted with your insurance plan, contact your insurance company and ask about obtaining authorization to receive treatment here.
View our pricing and billing
Provider based billing
No Surprise Billing
When you're treated by an out-of-network provider at an in-network facility, you are protected from balance billing. In these cases, you shouldn't be charged more than your plan's copayments, coinsurance and/or deductible. Learn about your rights and protections against surprise medical bills.
- Evaluation and Treatment Center (ETC): An outpatient clinic designed to evaluate established City of Hope patients with cancer-related concerns.
- Gift Shop: Carefully curated items for people with cancer, including inspirational books and specialty gifts.
- Hangar 22 at OC: Made-to-order healthy food options served with our signature hospitality and indoor/outdoor seating offering sunshine therapy.
Learn More About Campus Dining Options
- Four operating rooms and two procedure rooms designed to work as one surgical unit along with the three additional ORs in the outpatient center. Surgical services include the latest da Vinci robotic surgery systems, including DV5, which features haptic feedback, enhanced 3D visualization and increased arm dexterity for greater precision and efficiency.
- 14 pre-op bays and postanesthesia care units.
- Advanced imaging capabilities include real time fluoroscopy, ultrasound and X-ray imaging.
- Sterile Processing Department
- Lab & Blood Bank
- Grand Outdoor Terrace
- 20 patient rooms with ensuite bathrooms, large windows, visitor recliners and couches that can be converted to beds, original artwork, and a cozy blanket donated by Pacsun.
- An inpatient rehabilitation gym staffed by physical therapists with oncology expertise who provide safe and productive healing exercise for patients. The integrated cancer rehab program supports chemoradiation treatment concurrently with rehabilitation.
Learn More About Rehabilitative Services Offered - Outdoor Terrace
- 20 ICU beds for comprehensive and continuous care for critically ill patients.
- The Wetterau Family Spiritual Care Center: A first-of-its-kind immersive, multifaith spiritual care center that allows patients and their families to choose customized faith experiences featuring the sights, sounds and prayer candles from seven sacred spaces.
- Physician On-Call Room
- Medical Records
- Outdoor Terrace
- Medical-surgical unit: 17 beds
- Patient-family suites: Two suites include separate-but-connected guest room accommodations for loved ones.
- Physician On-Call Room
- Training Conference Room
- Outdoor Terrace
- Expert management and care for patients with complex blood cancers and disorders, including immunotherapy, targeted therapy, clinical trials and more. This floor features eight medical-surgical beds and eight ICU beds with positive air suites.
- A specialty pharmacy on this floor delivers breakthrough treatments for acute cancer patients.
- Multipurpose Rooms
- Outdoor Terrace
City of Hope's Evaluation and Treatment Center (ETC) is an appointment-based outpatient clinic designed to evaluate established City of Hope patients with cancer-related concerns.
City of Hope® Orange County has created the first multifaith spiritual care center designed to immerse cancer patients in their healing places. The Wetterau Family Spiritual Care Center, housed in City of Hope Orange County’s cancer specialty hospital, was intentionally designed to reflect the spiritual diversity of our community.
The Lennar Foundation Cancer Center is seamlessly connected to Orange County’s only cancer specialty hospital exclusively focused on treating and curing cancer. Together, the two make up the Irvine Academic Research Campus, exclusively focused on treating and curing cancer.
