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Orange County Newsroom

City of Hope Orange County leaders and physicians are available to provide commentary on a wide range of healthcare topics and cancer-focused news, trends and research. Interviews with leaders, physicians and patients or visits to the cancer center can be arranged by emailing:
A New City of Hope Orange County Report Reveals Concerning Trends About Cancer in Younger Adults in Southern California

City of Hope Orange County, the most advanced cancer research and treatment organization in Orange County, has released a report that evaluates the cancer incidence rate in people ages 18 and 49 in Orange County and Southern California amid a national epidemic of early-onset cancer diagnoses.

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Younger Face of Cancer

In the News

Sacituzumab or Dato-DXd? Experts Weigh First-Line ADCs in Metastatic TNBC

October 23, 2026

City of Hope's Hope S. Rugo, M.D. and City of Hope's Irene M. Kang, M.D., led a discussion comparing sacituzumab govitecan-hziy and datopotamab deruxtecan-dlnk as first-line antibody-drug conjugates for metastatic triple-negative breast cancer. Joined by other City of Hope oncologists, they reviewed efficacy and safety data from recent trials. Topics included treatment sequencing, toxicity management like neutropenia and diarrhea, how crossover complicates survival analyses and optimizing patient outcomes by considering adverse event profiles when choosing between ADCs.

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Metastatic Breast Cancer Clinical Trials: What Black Women Should Know

October 22, 2026

An article discusses metastatic breast cancer (mBC) clinical trials, emphasizing their importance for treatment advancement. City of Hope's Tingting Tan, M.D., Ph.D., explains that mBC patients require personalized, lifelong treatment and that clinical trials introduce new therapies when drug resistance occurs. Tan highlights the benefits of participation, including access to novel options and contributing to scientific research.

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Press Releases & Statements

Listen to Talking Hope

Hear breakthrough conversations about preventing, treating and curing cancer, brought to you by City of Hope, a National Cancer Institute-designated comprehensive cancer center offering Orange County’s most advanced cancer care. The Science of Cancer Survival Starts Here.

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Orange County Stories

Gynecologic cancer patient Faten Alsafadi and son Donatello
Oct 23, 2026
City of Hope Orange County
A Son's Love, a Mother's Hope: How One Family’s Search for Answers Led Them to City of Hope Orange County
Lifesaving gynecologic cancer care at City of Hope Orange County transformed this family’s journey.
Orange County
Patient Stories
Breast cancer survivor Caroline de Vaulx at a Pink Dragons dragon boat event
Oct 22, 2026
City of Hope Orange County
After Breast Cancer, She’s Charting New Waters — in a Dragon Boat
City of Hope Orange County grateful patient Caroline de Vaulx discovered a team of breast cancer survivors who helped her move forward, one synchronized stroke at a time.
Orange County
Patient Stories
Eagle Scout Kenny Smith and Mrs. Foy
Oct 20, 2026
City of Hope Orange County
A Garden of Hope: Eagle Scout Project Honors Legacy, Creates Lasting Impact
What began as an Eagle Scout project to refresh two garden areas in Celebration Plaza at City of Hope Orange County became something far more meaningful, bringing together remembrance, hope and community in a way no one could have anticipated.
Orange County
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Media Gallery

Annette Walker with grateful patients at Breast Cancer Awareness Month celebration
Pacific Symphony performance at a City of Hope event at South Coast Plaza
Dietitian Preeti Soni and chef during a City of Hope cooking demonstration
City of Hope “Hope Is a Rising Tide” art installation
City of Hope blue piano activation at Lido Marina Village

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