An NCI-designated Comprehensive Cancer Center
Wade Smith

Wade Smith, M.D.

Medical Oncologist
Clinical Expertise
Assistant Clinical Professor, Department of Medical Oncology & Therapeutics Research

Clinical Teams

Wade Michael Smith, M.D., brings his expertise and training in a variety of cancers to City of Hope | Newport Beach in his role as an oncologist and assistant clinical professor in the Department of Medical Oncology & Therapeutics Research.
After completing his Bachelor of Science degree in biology at Loyola Marymount University in Los Angeles, Dr. Smith received his M.D. at the Creighton School of Medicine at Creighton University Medical Center in Omaha, Nebraska, and completed his residency and fellowship at Emory University School of Medicine in Atlanta. He then relocated back to Southern California to continue his career in medical oncology.
Dr. Smith is particularly passionate about treating breast cancer. He cites a “lifelong fascination with biology” that has led to work exploring immunotherapy to treat chemotherapy-resistant cancers, particularly breast cancer.Helping to bring these immune-oncology treatments from ‘bench to bedside’ is a contribution I am most excited about,” Dr. Smith said.
Dr. Smith appreciates the way City of Hope has integrated itself seamlessly into the communities of Southern California, establishing itself as a premier not-for-profit cancer research and treatment center. “Combining the latest cutting-edge cancer research with the ancillary amenities provided through its community expansion means that I can offer the absolute best in patient-centered, compassionate care,” he said.


1601 Avocado Ave

Newport Beach, CA 92660

DeJoya-De Keyser R., Bencheqroun HK, Smith W. Not All That Cavitates in the Lung is TB (poster). American Thoracic Society International Conference 2014.
Smith W, Khuri F. The care of lung cancer patients in the 21st century: a new age. Seminars in Oncology, Vol. 31, No. 2, Suppl. 4(April), 2004: 11-15.
Smith W, Fanucchi M. Treatment of advanced non-small cell lung cancer in special populations. Oncology, Vol.18, No. 10(Sept.), 2004: 1326-1327.
Smith W, Saba N. Critical Reviews in Hematology and Oncology, Vol. 55, 2005: 143-152.