Comprehensive Cancer Center

The program’s mission is to advance the science and application of cancer etiology, prevention and outcomes research, and to reduce the burden of cancer across all segments of the population through collaborative, interdisciplinary, interventional and educational efforts. All research associated with Cancer Control and Population Sciences involves strong educational components, ranging from K-through-12 programs in the community to health care provider and caregiver training designed to enable better communication and care for cancer survivors.

Our team of cancer immunotherapeutics researchers are focused on the discovery and application of more specific and less toxic cancer therapies, and translating those therapies into clinical practice. Research in the program has yielded a growing portfolio of active investigational new drugs. New Food and Drug Administration-authorized therapies impact a growing number of patients, including those with glioma, lymphoma, childhood neuroblastoma and colorectal, breast and prostate cancers.

The search for more effective, less toxic treatments for cancer is an ongoing and vital pursuit at City of Hope. In our Developmental Cancer Therapeutics Program, research scientists and clinicians are collaborating closely to develop and evaluate novel therapies for cancer patient. The program team develops targeted and selective anti-cancer treatments to reduce the amount of collateral damage to normal tissues associated with many currently available treatments. These leading-edge studies are leading to greatly improved cancer therapies, with further advances expected to continue.

Bringing together clinical and basic scientists in dynamic ways, intensive studies within the leading-edge Hematologic Malignancies Program bring basic science research findings to the clinic to target and treat the transformed cells in the blood, lymph nodes and bone marrow that generate malignant blood cancers. The Hematologic Malignancies Program improves public health, particularly in the underserved populations in the catchment areas of the cancer center, both through its refinement of currently available treatment options for hematological malignancies and its advancement of novel therapies to the clinic.

The mission of the Molecular and Cellular Biology of Cancer Program is to advance basic research in cancer biology and accelerate the application of basic cancer science into the clinic for cancer prevention and therapeutics. To achieve this, the program brings together world-class investigators in the areas of DNA damage response and repair, RNA biology and therapeutics, cancer metabolism and oncogenic signaling.