An NCI-designated Comprehensive Cancer Center
Many research laboratories lack the means (and skilled technicians) to maintain sufficient breadth of advanced microscopy and image analysis technologies. At City of Hope, we support investigators whose research requires high-quality 2D, 3D, and 4D data sets, along with training and comprehensive service.  
 
Our research-grade facility and equipment perfectly enable the observation and documentation required for publications, grant proposals, and education. 
 
The Light Microscopy Digital Imaging Core makes available the latest research platforms for automated microscopy experiments, advanced observation techniques, and sophisticated digital image processing and analysis. Our team of researchers and technicians is comprised of experienced specialists who not only provide onboarding and instruction—they also work as consulting practitioners. 
 
The core facility has high-end workstations with the power, memory and graphics cards needed for handling large data sets. These workstations have state of the art image analysis software which can be accessed from other sites on campus. Training and support is available from core staff that have significant expertise in image analysis.  
   
Note: This core is not supported by the National Cancer Institute-funded Cancer Center Support Grant.

Meet the Team

Director, Light Microscopy Imaging Core

Abstract for Grants

The objective of the Light Microscopy Digital Imaging Core is to provide cutting edge microscopy systems and expertise to City of Hope investigators needing high quality light microscope images and data. Microscopy and imaging are rapidly evolving fields that depend increasingly on expensive equipment and skills beyond the means of most individual laboratories. We seek to provide a range of research-grade light and confocal microscope platforms for simple observations and documentation suitable for publications or grant proposals. The Light Microscopy Digital Imaging Core also makes available the latest research platforms for automated microscopy experiments, advanced observation techniques and sophisticated digital image processing and analysis.
 
Services
  • Instruction in general aspects of light and confocal microscopy
  • Instruction in general aspects of digital imaging and image analysis
  • Consultation on microscopy and imaging projects
     
Microscope Systems
  • Widefield: __________7 Fluorescent Systems
  • Live Cell Imaging: ____5 Zeiss Observers, 1 Nikon Biostation
  • Confocal: __________ 1 LSM700, 2 LSM880 Airyscan
  • 2-Photon: ___________1 Prairie Ultima with Coherent Chameleon
  • LaserMicroDissection: _1 Leica LMD7000
  • Digital Slide Scanner_Hamamatsu Nanozoomer HT2.0
  • Fluidigm Hyperion IMC
     
Imaging Software for Image Quantification and Presentation
  • Image Pro Premier
  • Imaris 3D
  • AMIRA 3D
  • Autoquant Deconvolution
  • Visiopharm