Shared Resources & Services

City of Hope and Beckman Research Institute offer a host of resources meeting researchers’ needs for specialized equipment, services or expert consultation. Sharing state-of-the-art equipment and resources, and the expertise to apply them to meaningful research, are crucial to the pursuit of new treatments and potential cures. They’re key pillars of our status as an NCI-designated Comprehensive Cancer Center.

 

Analytical Cytometry

The Analytical Cytometry Core Facility is providing researchers with high-quality flow cytometry instrumentation, as well as expertise in analyzing and/or sorting sample populations of interest via interpretation of their physical, fluorescent and/or light-scattering properties. The facilities and their services are available to both City of Hope and non-City of Hope researchers.

Analytical Pharmacology

The Analytical Pharmacology Core facility focuses on conducting pharmacokinetic and pharmacodynamic studies for both chemotherapy clinical trials and peer-reviewed preclinical studies.

Biostatistics Core Facility

The Biostatistics Core facility draws upon a talented group of statisticians who collaborate across basic, translational, clinical and population-oriented research at the City of Hope's Comprehensive Cancer Center.

Bioinformatics Core (BIC) Facility

City of Hope's Bioinformatics Core (BIC) Facility is providing researchers with high-throughput biological data analysis tools, data management, unified cyber-infrastructure, training, as well as trained staff working with multidisciplinary team to facilitate experimental design, information management, data integration, annotation, dissemination and visualization.

Biological & Cellular GMP Manufacturing Facility

The Center for Biomedicine and Genetics and the Cellular Therapies Production Center are empowering scientific and clinical investigators with the freedom to test and refine the most promising new therapeutics

Chemical GMP Synthesis Facility

The Chemical GMP Synthesis Facility (CGSF) is a state-of-the-art manufacturing resource for small and large molecule therapeutics for clinical trials.

Clinical Immunobiology Correlative Studies (CICSL)

The Clinical Immunobiology Correlative Studies (CICSL) is a centralized facility supporting development and implementation of cutting-edge, immune-correlative studies to support clinical trial protocols in the Cancer Center.

Computational Therapeutics Core

The overall goal of the Computational Therapeutics Core facility is to rationalize and provide insights to experimental data in molecular biology, further make predictions on protein structures and dynamics to generate hypothesis for newer experiments to be done and design small molecule and biologics targeting proteins for therapeutic purposes.

Cytogenetics Core Laboratory

Our Cytogenetics Core Laboratory provides classic and molecular cytogenetics services to Beckman Research Institute researchers, as well as non-City of Hope investigators.

Design and Fabrication Laboratory

The design and fabrication laboratory was established in 1970 as part of Biomedical Instrumentation Services Department and provides design and fabrication services.

Drug Discovery and Structural Biology Core

The DDSB Core technically and scientifically facilitates research into new, more effective and less toxic therapies for the treatment of cancer.

Electron Microscopy and Atomic Force Microscopy

City of Hope’s Electron Microscopy and Atomic Force Microscopy Core is allowing researchers to take sharper, closer looks at the building blocks of biological life.

Gene Editing and Viral Vector Core (Coming Soon)

The Gene Editing and Viral Vector Core will develop gene editing tools for manipulating mammalian genomes and deliver these tools into cells using viral vectors.

High Throughput Screening

The High Throughput Screening (HTS) Core is assisting researchers in the identification of novel lead compounds for the development of anticancer drugs and of chemical probes useful for biochemical mechanistic studies.

Integrative Genomics Core

The Integrative Genomics Core is committed to providing high quality, efficient, comprehensive, and cost effective genomic services to City of Hope researchers using microarray and high- throughput sequencing technologies. It also provides basic and advanced data analysis services to make complex data biologically interpretable for clinical and basic scientists.

Light Microscopy/Digital Imaging

Our Light Microscopy Digital Imaging Core is providing services, facilities and expertise to City of Hope investigators needing high quality light microscope images.

Mass Spectrometry & Proteomics

The Mass Spectrometry and Proteomics Core is enabling high-quality mass analysis of biomolecules - proteins, glycoproteins, peptides, oligonucleotides, nucleic acids, lipids and small-molecule metabolites - for a variety of biomedical investigations. The facility offers supporting techniques as well as scientific consultation.

Nuclear Magnetic Resonance Core

The NMR Core facility focuses on applying high resolution NMR spectroscopy to the structural characterization of biomolecules, small organic compounds, natural products, and biomolecular complexes.

Office of Technology Licensing (OTL)

The Office of Technology Licensing works closely with City of Hope inventors in identifying, creating and protecting effective strategies to commercially advance their inventions and technologies.

Office of IND Development and Regulatory Affairs (OIDRA)

OIDRA helps City of Hope investigators in interacting with governmental regulatory agencies and remaining in compliance with United States Food and Drug Administration requirements.

Pathology Core

The Pathology Core at City of Hope provides optimally preserved tumors and normal tissue samples to researchers. Supported by the Cancer Center Support Grant with funding from the National Cancer Institute, the Pathology Core maintains a bank of several thousand diverse tumor samples.

Small Animal Imaging Core

Imaging of small animals has become indispensable to medical research and to scientific developments, helping investigators remain competitive for extramural funding. The SAIC provides a diverse spectrum of exciting services and benefits.

Stem Cell Core (Coming Soon)

The COH/BRI Stem Cell Core Facility aims to accelerate stem cell research at COH by providing critical stem cell resource and technical support.

Survey Research Core

The Survey Research Core (SRC) is a shared resource helping investigators conduct research using survey methodology. The SRC offers a wide range of services in the areas of study design and sampling, survey instrument development and evaluation, data coding, collection, management, analysis and reporting.

Synthetic and Biopolymer Chemistry Core

The Synthetic and Biopolymer Chemistry Core (SBCC) is providing both biopolymer and small-molecule synthetic services to scientists.

Translational Biomarker Discovery Core

The Translational Biomarker Discovery Core is providing Biomarker discovery services to basic scientists and clinicians doing research being applied to improving clinical outcomes for patients.

X-ray Crystallography Core Facility

The X-ray Crystallography Core give researchers access to a state-of-the-art facility for the generation of crystals and structure determination of macromolecules including proteins, DNA, RNA, and complexes between macromolecules and their ligands.