Gene Editing and Viral Vector Core
The Gene Editing and Viral Vector Core (GEVVC) serves as a supporting facility for City of Hope’s principal investigators, whose primary interest involves genetic engineering of human and mouse genomes for basic research and therapeutic disease treatment. The missions of the core include:
- Using gene editing techniques to modify the genome of animals, cultured human/mouse cell lines, primary cells, including hematopoietic stem cells and pluripotent stem cells;
- production of infectious lentiviral and retroviral vector for gene delivery into culture cells;
- production of adenoviral vector (AdV) and adeno-associated vector (AAV) for direct gene delivery into animal in vivo or primary cells in vitro.
Using the Facility
- Using gene-editing techniques to modify the genome of animals, cultured human/mouse cell lines, primary cells, including hematopoietic stem cells and pluripotent stem cells
- Production of infectious lentiviral and retroviral vector for gene delivery into culture cells
- Production of adenoviral vector (AdV) and adeno-associated vector (AAV) for direct gene delivery into animal in vivo or primary cells in vitro
Meet the Team
Leadership
Core Staff
Tammy Chang
Senior Research Associate
626-256-4673, ext. 84093
[email protected]
Victor Huang
Research Associate II
[email protected]
Rita Zhang
Research Associate I
[email protected]
Contact the Team
Current pricing can be found on iLab Solutions.
Our Publications
Miao, Y., Ajami, N.E., Huang, TS. et al.
City of Hope is focused on basic and clinical research in cancer, diabetes and other life-threatening diseases.
Equipment
In a given year, City of Hope conducts more than 400 clinical trials enrolling more than 6,000 patients.
