"Every patient has a unique story. My goal is to provide every breast cancer patient with several treatment options, based on their stage of disease, individual personal values and family history.”
Laura L. Kruper, M.D., M.S., led a major study which discovered that 7 out of 10 women who get mastectomies to treat breast cancer do not undergo reconstructive surgery. She wants to change that, especially after hearing from her minority and lower-income patients who were denied the option at other hospitals.
“One of my goals is to make things a little more equal for everybody,” she said.
A graduate of University of Pennsylvania School of Medicine, Dr. Kruper has over 15 years' experience as a cancer surgeon. At City of Hope since 2008, she strives to optimize the treatment of breast cancer through clinical trials, getting the best available therapies to patients as quickly as possible.
A frequently sought-after medical expert for television news and talk shows, Dr. Kruper is passionate about improving breast cancer awareness and education.
2008, California Fluoroscopy Operators Permit Certification
2008, American Board of Surgery Certification
2007, California Medical License
2004, DEA License
2001, Pennsylvania Medical License
2000, Connecticut Medical License
2015, Stanford Executive Program for Women Leaders, Stanford University, Stanford, CA
2005, University of Pennsylvania, Center for Clinical Epidemiology & Biostatistics, Philadelphia, PA, M.S., Health Services and Outcomes Research
2000, University of Pennsylvania School of Medicine, Philadelphia, PA, M.D.
1989, Brown University, Providence, RI, B.A., Egyptology, Magna Cum Laude
2007-2008, Breast Oncology Fellow, John Wayne Cancer Institute, Santa Monica, CA
2001-2007, Surgical Resident, Hospital University of Pennsylvania, Philadelphia, PA
2000-2001, Surgical Intern, Yale New Haven Hospital, Yale University, New Haven, CT
2019-present, Assistant Clinical Professor and Chief, Division of Breast Surgery, Department of Surgery, City of Hope, Duarte, CA
2012 - Present, Director, Women's Center, City of Hope, Duarte, CA
2008 - 2019, Assistant Clinical Professor and Surgeon, Head of Breast Surgery Service, Division of Surgical Oncology, Department of Surgery, City of Hope, Duarte, CA
1999, Teaching Assistant, University of Pennsylvania School of Medicine, Department of Anatomy and Physiology
1995-1996, Research Assistant, The Wistar Institute, University of Pennsylvania, Philadelphia, PA
1995, Teaching Assistant, Bryn Mawr College, Department of Chemistry
1990-1993, Assistant Photo Editor, Condé Nast Traveler Magazine, New York, NY
My long-term academic and research objectives are to optimize the management of breast cancer through better clinical trials. I believe one way to work toward this objective is to translate current scientific research findings from basic bench research into clinical studies and eventually clinical practice.
Awards & Memberships
2011-2015, Pasadena Top Doctors
2007, Lynn Sage Breast Cancer Fellow Travel Grant
2003-2005, National Institutes of Health National Research Service Award University of Pennsylvania Center for Clinical Epidemiology
2000, Alpha Omega Alpha University of Pennsylvania School of Medicine
1999, National Institutes of Health Cancer Grant
1997, National Institutes of Health Short Term Research Grant
1989, Brown Alumni Prize for Academic Excellence
1987, Dorot Archaeological Travel Grant
2009, American College of Surgeons Oncology Group
2009, Southwestern Oncology Group
2009, American Society of Breast Surgeons
2009, American College of Surgeons, So. California Chapter
2007, Society of Surgical Oncology
2001, American College of Surgeons
Kruper L, Low DW, Bucky LP. Immediate Pectoralis Flap Closure Following Septic Arthritis of the Manubriosternal Joint. Plast Reconstr Surg 2001;107(4):997-9.
Kruper L, Tchou J. The Breast. In: Kaiser LR, ed. The Surgical Review: An Integrated Basic and Clinical Science Study Guide. 2nd ed. Philadelphia: Lippincott 2005.
Kruper L, Sonnad SS. Statistics and Epidemiology. In: Kaiser LR, ed. The Surgical Review: An Integrated Basic and Clinical Science Study Guide. 2nd ed. Philadelphia: Lippincott 2005.
Kruper L, Schuchter L. Malignant Melanoma and non-Melanoma Skin Cancer. In: Muss HB, Hunter CP, and Johnson KA, eds. Multidisciplinary Treatment and Management of Cancer in the Elderly. New York: Taylor & Francis Group 2006.
Kruper L, Spitz F, Czerniecki BJ, Blackwood-Chirchir A, Elder DE, Fraker DL, Guerry D, Ming M, Schuchter LM. Gimotty PA. Predicting sentinel node status in clinical stage I/II melanoma. Cancer, 2006; 107(10):2436-45.
Kruper L, Kurichi JE, Sonnad SS. Methodological quality of cost-effectiveness analyses of surgical procedures. Annals of Surgery, 2007; 245(1):147-151.
Kruper L, Giuliano AE. A randomized clinical trial on sentinel lymph node biopsy versus axillary dissection: A matter of technique. Annals of Surgery, 2008; 247(2):214-216.
Kruper L, Giuliano AE. Preoperative identification of the sentinel lymph node in breast cancer. Breast Diseases: A Year Book Quarterly, 2008; 19(3): 238-9.
Kruper L, Giuliano AE. Breast disease. In Practical Gynecologic Oncology, ed. Berek JS, Hacker, NF. 5th edition. Williams & Wilkins, Philadelphia, 2009.
Pal SK, Lau S, Kruper L, Nwoye U, Garberoglio C, Gupta RK, Paz IB, Vora L, Guzman E, Artinyan A, Somlo G. Papillary Carcinoma of the breast: An Overview. Breast Cancer Res Treat, 2010;122(3): 637-45.
Kruper L, Holt A, Xu X, Duan L, Henderson K, Bernstein L, Ellenhorn J. Disparities in reconstruction rates after mastectomy: Patterns of care and factors associated with the use of breast reconstruction in Southern California. Ann Surg Oncol 2011;18:2158-65..
Kounalakis N, Pezner R, Kruper L. Partial breast irradiation in a patient with bilateral breast cancers and CREST Syndrome. Brachytherapy, 2011;10:486-90.
Wiatrek R, Kruper L. Sentinel lymph node biopsy indications and controversies in breast cancer. Maturitas, 2011;69:7-10.
Kruper L, Xin Xin X, Henderson K, Bernstein L. Disparities in reconstruction rates after mastectomy for ductal carcinoma in situ (DCIS): Patterns of care and factors associated with the use of breast reconstruction for DCIS as compared to invasive cancer. Ann Surg Oncol 2011;18:3210-9.
Pal SK, Dehaven M, Nelson RA, Onami S, Waliany S, Hsu J, Kruper L, Mortimer J.
Impact of modern chemotherapy on the survival of women presenting with de novo metastatic breast cancer. BMC Cancer,2012;12:435.
Oxner CR, Vora L, Yim J, Kruper L, Ellenhorn JDI. Magnetic resonance-guided breast biopsy in lesions not visualized by mammogram or ultrasound. Am Surg, 2012;78:1087-90.
Kruper L, Henderson K, Xu X, Bernstein L, Chen S. Utilization of mastectomy and reconstruction in the outpatient setting. Ann of Surg Oncol, 2013;20:828-35.
Priceman SJ, Kujawski M, Shen S, Cherryholmes GA, Lee H, Zhang C, Kruper L, Mortimer J, Jove R, Riggs AD, Yu H. Regulation of adipose tissue T cell subset by stat3 is crucial for diet-induced obesity ad insulin resistance. Proc Natl Acad Sci 2013;110:13079-13084.
Arrington A, Kruper L, Vito C, Yim JH, Kim J, Chen SL. Rural and urban disparities in the evolution of sentinel node utilization in breast cancer. Am J Surg 2013;206:674-81.
Arrington A, Nelson R, Chen S, Vito C, Yim J, Kruper L. The Decision to Undergo Prophylactic Mastectomy and Subsequent Satisfaction: The patient perspective. Ann Surg Oncol. (Under Revision)
Uyeno LA, Goldstein L, Chen SL, Yim JH, Kruper L. Hospital readmissions and post-operative complications following outpatient mastectomy. (Submitted)
Arrington A, Goldstein L, Kruper L, Vito C, Yim JH, Chen SL. Life expectancy after curative-intent treatment of breast cancer: Impact on long-term follow-up care. Am J Surg 2014;80:604-9.
Kruper L, Kauffmann R, Smith D, Nelson R. Survival analysis of contralateral prophylactic mastectomy: A question of selection bias? Ann Surg Oncol 2014;21:3448-56.
Miller M, Ottesen R, Niland J, Kruper L, Chen S, Vito C. Lymph Node Ratio is a Prognostic Indicator of Overall Survival for Non-Metastatic Breast Cancer Patients after Neoadjuvant Chemotherapy. Ann Surg Oncol 2014;21:3317-23. PMID: 25059788.
Mortimer J, Jung J, Yuan Y, Kruper L, Stewart D, Chung S, Yu KM, Mendelsohn M, D’Apuzzo M, Tegtmeier B, Dadwal S. Skin/Nail infections with the addition of pertuzumab to trastuzumab-based chemotherapy. Breast Cancer Res Treat 2014;148:563-70.
Bitz C, Clark K, Vito C, Kruper L, Ituarte PHG, Loscalzo M. Partners’ Clinic: An innovative gender strengths-based intervention for breast cancer patients and their partners immediately prior to initiating care with their treating physician. Psycho-Oncology 2015;24:355-8.
Schinde AM, Zhai J, Yu KW, Frankel P, Yim JH, Luu T, Kruper L, Vito C, Shaw S, Vora NL, Kirschenbaum M, Somlo G. Pathologic complete response rates in triple-negative, HER2-positive, and hormone receptor-positive breast cancers after anthracycline-free neoadjuvant chemotherapy with carboplatin and paclitaxel with or without trastuzumab. Breast 2015;24:18-23.
Kauffmann R, Bitz C, Clark K, Loscalzo M, Kruper L, Vito C. Addressing psychosocial needs of partners of breast cancer patients: a pilot program using social workers to improve communication and psychosocial support. Support Care Cancer 2015.
Patel SK, Wong AL, Wong FL, Breen EC, Hurria A, Smith M, Kinjo C, Paz IB, Kruper L, Somlo G, Mortimer JE, Palomares MR, Irwin MR, Bhatia S. Inflammatory Biomarkers, Comorbidity, and Neurocognition in Women With Newly Diagnosed Breast Cancer. J Natl Cancer Inst 2015;107:1-7.
Merchant S, Goldstein L, Kruper L. Patterns and trends in immediate post-mastectomy reconstruction in California: Complications and unscheduled admissions. Plast Reconstr Surg 2015;136:10-19.
Ratings and reviews below are gathered from the Press Ganey Clinician and Group Consumer Assessment of Healthcare Providers and Systems (CG CAHPS) survey. CG CAHPS is a standardized survey that is used to measure a patient's experience in the physician office setting. Ratings are an average of all responses to questions about a provider's care, with 5 stars being the highest.
Provider explain in way you understand
Provider listen carefully to you
Know important info medical history
Show respect for what you say
Spend enough time with you
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Recommend this provider office
Dr Kruper has always been attentive, professional and a very empathetic care provider. - Verified patient
Dr. Kruper is an excellent physician, but also an extraordinary person. She displays compassion and a deep interest in the well being of her patients, far beyond basic medicine. And truly fulfills the City of Hope spirit of "not just treating the body, but also caring for the soul. - Verified patient
The doctor was highly recommended. She met all of my expectations. Very competent & very good communicator. - Verified patient
[...] in the Women's Center were fantastic in their delivery of care and support during my annual appointment for a mammogram, ultra-sound and follow up visit with Dr. Kruper. All were professional, proficient, thorough and efficient in rendering service and care during my visit. - Verified patient
Amazing how staff went out of the way to contact drs. and schedule appointment. They are like angels. A 15 on a scale of 10. - Verified patient