Neuroblastoma, Wilm's Tumors and other Pediatric Cancers

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The Pediatric Oncology Program at City of Hope offers comprehensive, family-centered, leading-edge treatment for childhood, adolescent and young adult (AYA) patients with neuroblastoma, Wilms Tumor and a wide variety of other benign and malignant solid tumors that require expert care to offer the best chance of cure.

City of Hope, located near Los Angeles, California, is a nationally recognized leader in the research and treatment of neuroblastoma, Wilms Tumors and other pediatric cancers. We have been named a best hospital for cancer by U.S. News & World Report for over a decade and a National Cancer Institute comprehensive cancer center, the highest designation that recognizes our commitment to cancer treatment, research and education.

As a founding member of the National Comprehensive Cancer Network, our doctors also help develop and improve evidence-based cancer treatment guidelines for patients throughout the country.


What is neuroblastoma?

Neuroblastoma, a cancer that develops in immature nerve cells, represents a diagnostic and treatment dilemma that requires expert understanding of the tumor’s biology. At City of Hope, our ground-breaking work in both laboratory science and patient care gives us the experience to determine whether the individual diagnosis calls for observation or for the most aggressive approach.
City of Hope is a member of the Children’s Oncology Group (COG), which provides access to the nation’s largest group of pediatric and adolescent clinical trials for neuroblastoma with treatments that include chemotherapy, autologous hematopoietic cell transplant (HCT), retinoic acid therapy and antibody therapy (anti-Ch14.18) for aggressive neuroblastoma. City of Hope scientists are working on several research initiatives to develop new therapies for neuroblastoma. Pediatric team members are collaborating on research efforts to bring these therapies to clinical practice.

What is Wilm's Tumor?

Wilm’s tumor is a cancer of the kidney that is curable in most diagnosed children, with a survival rate of more than 90 percent. Usually only surgery and chemotherapy are needed to successfully treat Wilm’s tumor, but in difficult cases, more aggressive treatment, including radiation therapy, may be required. Our long-standing expertise in autologous hematopoietic cell transplant (HCT) enables aggressive treatment in patients with very advanced disease.
City of Hope is a member of the Children’s Oncology Group (COG), which provides access to the nation’s largest group of pediatric and adolescent clinical trials for Wilms tumor.

Other pediatric solid tumors

Children, adolescents and young adults can have many other types of tumors. As a National Cancer Institute-designated Comprehensive Cancer Center, City of Hope is prepared to deliver the best care available with its experienced pediatric oncology team. City of Hope is a member of the Children’s Oncology Group (COG), which provides access to the nation’s largest group of pediatric and adolescent clinical trials for the variety of cancers seen in children, adolescents and young adults. City of Hope offers expert treatment for the following diseases:
  • Germ cell tumors
  • Testicular or ovarian tumors
  • Thyroid cancer*
  • Melanoma
  • Carcinoma of head/neck, including larynx or tongue
  • Rare tumors of children, adolescents and young adults
*City of Hope is one of an elite few centers in Southern California offering comprehensive care with collaboration between endocrinology and pediatric oncology.

Neuroblastoma, Wilm’s tumor and the other tumors seen in children, adolescents and young adults require a team of experienced professionals to provide comprehensive and family-centered care.  At City of Hope, our pediatric team specializes in the treatment of children, adolescents and young adults from birth to 30 years of age. The team includes social workers; child life specialists; recreation, occupational and physical rehabilitation therapists; school reintegration specialists; nutritionists; psychologists; neuropsychologists; and spiritual care specialists.

Pediatric Hematology-Oncology

Clarke Anderson, M.D.

Clinical Specialties

  • Pediatric Hematology-Oncology

Pediatric Hospital Medicine

Julie F. DiMundo, D.O.

Clinical Specialties

  • Pediatric Hospital Medicine

In addition to the best medical care available, City of Hope also provides patients and their families access to several programs that include:

Late effects/survivor clinic follows patients long after their treatment to identify, treat and counsel for any issue that can arise related to their life-saving treatmentWhen you come to City of Hope, you automatically gain access to an unparalleled array of support services to help you and your family take each step during and after your brain tumor treatment. We can help with all of these concerns, and more:

  • Managing side effects and symptoms
  • Pain management
  • Navigating the health care system
  • Your emotional, social and spiritual health
  • Handling and coping with stress
  • Staying healthy and active
  • Healthy cooking and eating
  • Healing arts
  • Caregiver skills
  • Restoring normalcy in your family, job or school routine

Learn more about these resources at our Living with Cancer or Supportive Care Medicine sites.

The pediatric psychosocial team

Natalie Kelly, Ph.D., ABPP
Assistant Clinical Professor, Department of Supportive Care Medicine
Director, Neuropsychology Clerkship
Amy Tafel, M.S.W.
Pediatric Social Worker, Sheri & Les Biller Patient and Family Resource Center
Kayla Fulginiti, M.S.W.
Surgery/Medical Oncology Social Worker, Department of Supportive Care Medicine
Jeanelle Folbrecht, Ph.D.
Chief and Associate Clinical Professor, Division of Psychology, Department of Supportive Care Medicine