Neuroblastoma, Wilms' Tumors and Other Pediatric Cancers Treatments

Neuroblastoma, Wilms' Tumors and Other Pediatric Cancers Treatments

What is neuroblastoma?

Neuroblastoma, a cancer that develops in immature nerve cells, represents a diagnostic and treatment dilemma that requires expert understanding of the tumor’s biology. At City of Hope, our ground-breaking work in both laboratory science and patient care gives us the experience to determine whether the individual diagnosis calls for observation or for the most aggressive approach.
 
City of Hope is a member of the Children’s Oncology Group (COG), which provides access to the nation’s largest group of pediatric and adolescent clinical trials for neuroblastoma with treatments that include chemotherapy, autologous hematopoietic cell transplant (HCT), retinoic acid therapy and antibody therapy (anti-Ch14.18) for aggressive neuroblastoma. City of Hope scientists are working on several research initiatives to develop new therapies for neuroblastoma. Pediatric team members are collaborating on research efforts to bring these therapies to clinical practice.
 

What is Wilms' Tumor?

Wilms' tumor is a cancer of the kidney that is curable in most diagnosed children, with a survival rate of more than 90 percent. Usually only surgery and chemotherapy are needed to successfully treat Wilms' tumor, but in difficult cases, more aggressive treatment, including radiation therapy, may be required. Our long-standing expertise in autologous hematopoietic cell transplant (HCT) enables aggressive treatment in patients with very advanced disease.
 
City of Hope is a member of the Children’s Oncology Group (COG), which provides access to the nation’s largest group of pediatric and adolescent clinical trials for Wilms tumor.
 

Other pediatric solid tumors

Children, adolescents and young adults can have many other types of tumors. As a National Cancer Institute-designated Comprehensive Cancer Center, City of Hope is prepared to deliver the best care available with its experienced pediatric oncology team. City of Hope is a member of the Children’s Oncology Group (COG), which provides access to the nation’s largest group of pediatric and adolescent clinical trials for the variety of cancers seen in children, adolescents and young adults. City of Hope offers expert treatment for the following diseases:
  • Germ cell tumors
  • Testicular or ovarian tumors
  • Thyroid cancer*
  • Melanoma
  • Carcinoma of head/neck, including larynx or tongue
  • Rare tumors of children, adolescents and young adults
 
*City of Hope is one of an elite few centers in Southern California offering comprehensive care with collaboration between endocrinology and pediatric oncology.