Pediatric Cancers

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Each year, more than 15,000 children in the U.S. are diagnosed with cancer. At City of Hope, your child will be cared for by a dedicated team of world-class professionals specially trained in pediatric cancer.

Pediatric oncologists, hematologists, surgeons, radiation therapists, pathologists and others work together to develop targeted and effective treatment plans, while professionals in psychology, social work, physical therapy, occupational therapy, recreational therapy, music therapy and school reintegration provide support to patients and their families.

Request an Appointment

If your child have been diagnosed with a pediatric cancer or are looking for a second opinion consultation about your treatment, request an appointment online or contact us at 800-826-HOPE. Please visit Making Your First Appointment for more information.

City of Hope is a member of the Children's Oncology Group which maintains rigorous staffing, services and facilities standards for treating children's cancer. 90 percent of all pediatric cancer cases in the U.S. are treated at COG institutions. 

Through COG, City of Hope has access to the nation's largest group of clinical trials for pediatric and adolescent cancers.

We specialize in the treatment of cancers and blood disorders that occur most often in children, adolescents and young adults, including:



Pediatric cancer treatment options

City of Hope specializes in the treatment of childhood cancers and blood disorders, including:

  • Multiple types of leukemia, including acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML) and chronic myelogenous leukemia (CML)
  • Hodgkin and non-Hodgkin lymphomas
  • Musculoskeletal tumors, such as osteosarcoma, Ewing sarcoma, chondrosarcoma, rhabdomyosarcoma and soft tissue sarcomas
  • Brain tumors: astrocytoma, medulloblastoma and retinoblastoma
  • Neuroblastoma
  • Reproductive system tumors: Wilm’s tumor and germ cell tumors
  • Head and neck cancers, including cancers of the oral and nasal cavities, throat, sinuses, thyroid and salivary glands
  • Bleeding and clotting diseases: hemophilia, Idiopathic Thrombocytopenic Purpura (ITP), blood clots and platelet disorders
  • Red blood cell disorders: various forms of anemia, sickle cell disease and iron deficiency
  • Bone marrow and neutrophil disorders: aplastic anemia, storage diseases and neutropenia
  • Hematopoietic cell transplant (HCT), bone marrow transplant and cord blood transplant

Most pediatric cancers grow rapidly but also respond very well to chemotherapy. Survival rates are excellent, averaging 80 percent or higher. But cancers in children can also trigger long-term health challenges later in life, making follow-up care and regular monitoring especially important.

With the ever-increasing number of survivors of childhood cancer, we also emphasize long-term survivorship, providing continued surveillance to monitor and proactively address the long-term effects of childhood cancer.

City of Hope’s renowned pediatric physicians and researchers utilize the latest in technology and innovation to treat cancer, coupled with our enduring belief in providing unparalleled compassionate care. Call 800-826-HOPE or go online to request an appointment.

Pediatric Hematology-Oncology

Clarke Anderson, M.D.

Clinical Specialties

  • Pediatric Hematology-Oncology
Saro H. Armenian, D.O., M.P.H.

Clinical Specialties

  • Pediatric Hematology-Oncology
Nicole A. Karras, M.D.

Clinical Specialties

  • Pediatric Hematology-Oncology
Anna Pawlowska, M.D.

Clinical Specialties

  • Pediatric Hematology-Oncology
Joseph Rosenthal, M.D., M.H.C.M.

Clinical Specialties

  • Pediatric Hematology-Oncology
Judith K. Sato, M.D.

Clinical Specialties

  • Pediatric Hematology-Oncology
Leo David Wang, M.D., Ph.D.

Clinical Specialties

  • Hematopoietic stem cell transplantation
  • Pediatric hematology-oncology

Pediatric Hospital Medicine

Vincent Chan, M.D.

Clinical Specialties

  • Pediatric Hospital Medicine
Julie F. DiMundo, D.O.

Clinical Specialties

  • Pediatric Hospital Medicine

Pediatric Infectious Diseases

John A. Zaia, M.D.

Clinical Specialties

  • Pediatric Infectious Diseases

Pediatric cancer research and clinical trials

At City of Hope, we take the advances made by researchers in our laboratories and turn them into lifesaving therapies as quickly as possible. Many of these new therapies are not always available elsewhere. Browse through our current clinical trials and research projects here.

Childhood Cancer Suvivorship Program

The Childhood Cancer Survivorship Program at City of Hope provides specialized follow-up care for patients who have completed treatment for cancer or a similar illness that was diagnosed at age 21 or younger.  Patients who participate in this program are seen every year in a clinic specially designed to meet the needs of childhood cancer survivors.  Patients are evaluated by a team of health care professionals who are experts in survivorship issues, including a physician or nurse practitioner, a dietitian, and a psychologist or social worker.

Patients in this program will receive careful monitoring for possible health problems that can sometimes occur after cancer treatment. They will also have the opportunity to talk with the Survivorship Program team about the treatment that they received for cancer, its potential impact on their health, and ways to stay as healthy as possible.

Each patient will receive a personalized record of the details of their cancer treatment. They will also be provided guidelines for continued monitoring, including recommendations for preventive care and information about available resources and services.  The goal is to help each survivor stay healthy and to prevent any subsequent problems or detect them as early as possible so they can be more easily treated.

This program is carried out in collaboration with each patient’s primary health care and treatment team and is part of the research program here at City of Hope. For more information, please visit our Childhood Cancer Survivorship Program page, call 626-471-9220 or email us at [email protected].


Hannah Komai | City of Hope
Hannah, bone cancer survivor

Today, Hannah Komai is cancer-free and her story has come full circle: She's now a registered nurse at City of Hope, where she serves on the very same pediatric floor where she was once a patient.

Nicole Schulz Success Story Image
Nicole, leukemia survivor

After two bone marrow transplants and tremendous perseverance, Nicole is back to living the life she once knew – and making up for lost time.

Gavin's Wish: Meet My Bone Marrow Donor

A 6-year old boy is given the opportunity to meet the bone marrow donor who saved his life.

Adi and Kari's Story

Adi was diagnosed with Stage 4 neuroblastoma, a cancer of the nervous system that started on his adrenal gland and spread to his bone marrow.

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