Retroperitoneal Sarcoma Facts

What Is Retroperitoneal Sarcoma?

5 major histologic types for retroperitoneal sarcoma
Five major histologic types

The retroperitoneum refers to the back of the abdomen (e.g., where the kidneys are located).

Approximately 15-20% of soft tissue sarcomas develop in the retroperitoneum. Soft tissue sarcomas that grow in this region are called retroperitoneal sarcoma (RPS).

The most common type of retroperitoneal sarcoma is liposarcoma, which arises from fat. Others include leiomyosarcoma (smooth muscle), solitary fibrous tumor, undifferentiated pleomorphic sarcoma, malignant peripheral nerve sheath tumor.

Retroperitoneal sarcoma, especially liposarcoma, are typically large tumors.

What Causes Retroperitoneal Sarcoma?

This is unknown. In retroperitoneal liposarcoma, there is no association with obesity, fatty foods, or other potential risk factors.