Sarcoma Treatment and Survival Rate

January 22, 2026

This page was reviewed under our medical and editorial policy by Lee Cranmer, M.D., Ph.D., professor, Department of Medical Oncology & Therapeutics Research, City of Hope® Cancer Center Duarte.

Due to their unique nature in terms of the types and locations affected, sarcomas require a personalized treatment plan designed to produce strong clinical and quality-of-life outcomes.

Who Treats Sarcoma?

Depending on the type of sarcoma, the stage, where it’s located and other factors, one or more of the following specialists may be part of the patient’s care team: 

  • Medical oncologists, who specialize in the use of medicine to treat cancer, such as chemotherapy drugs
  • Surgical oncologists, who are trained to operate on cancerous tumors
  • Orthopedic surgeons, who specialize in treating and operating on bones, muscles and joints
  • Radiation oncologists, who specialize in using radiation to treat cancerous tissue
  • Pathologists, who evaluate biopsies, tissue and tumors as part of the diagnosis and treatment management process
  • Thoracic surgeons, who are trained to operate on tumors that develop in muscles or bones located in the chest
  • Gynecologic oncologists, who specialize in treating cancers affecting women’s reproductive organs (for conditions such as uterine sarcoma)
  • Radiologists, who use diagnostic radiology tools to diagnose sarcoma and evaluate whether cancer has spread
  • Specialized pharmacies, which supply medications that are difficult to find elsewhere, often for hard-to-treat conditions
  • Supportive care providers, who manage cancer- and treatment-related side effects and symptoms

Treatment for Sarcoma

The care team will work with the patient to create a sarcoma treatment plan tailored to his or her sarcoma stage, type, location and other factors. Treatment options may include surgery, radiation therapy, chemotherapy, targeted drug therapy, immunotherapy and/or combinations of these options. 

Learn more about the treatment options by type of sarcoma:

Sarcoma Survival Rate

Sarcoma survival rates vary greatly depending on the type and stage of disease. Learn more about the survival rates of these sarcoma subtypes: 

Sarcoma Treatment at City of Hope

At City of Hope, our multidisciplinary team of medical experts across different fields — including surgery, radiation oncology, medical oncology, pathology, rehabilitation and supportive care medicine — will review your individual case together to determine the best course of therapy. 

Our physicians are active members in many collaborations and cooperative groups, such as WEST (Western Sarcoma Team) and Children’s Oncology Group. Our team also participates in numerous clinical trials for detecting, treating and preventing sarcomas. This dedication to research means our patients have access to the most promising and leading-edge cancer therapies available.

References
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  • National Cancer Institute, NCI Dictionary of Cancer Terms. Sarcoma. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/sarcoma
  • American Cancer Society. Key statistics for soft tissue sarcomas, January 12, 2023. https://www.cancer.org/cancer/types/soft-tissue-sarcoma/about/key-statistics.html
  • American Cancer Society. Key statistics about bone cancer, January 17, 2024. https://www.cancer.org/cancer/types/bone-cancer/about/key-statistics.html
  • American Cancer Society. What is a soft tissue sarcoma? November 23, 2021. https://www.cancer.org/cancer/types/soft-tissue-sarcoma/about/soft-tissue-sarcoma.html
  • StatPearls [Internet]. Sarcoma, August 14, 2023.
    https://www.ncbi.nlm.nih.gov/books/NBK519533/