Karamjeet Singh Sandhu, M.D.
- Leukemia
- Hematology & Hematopoietic Cell Transplantation
- Leukemia in Geriatric Population
- Infections and Survivorships in Hematopoietic Stem Cell Transplant Recipients.
- Assistant Professor, Division of Leukemia, Department of Hematology & Hematopoietic Cell Transplantation
- Program Director, HCT/Cellular Therapy Fellowship Program
Location
Duarte Cancer Center
Duarte, CA 91010
Education & Experience
2016-present, Hematology
2015-present, Medical Oncology
2013-present, American Board of Internal Medicine
1994-2000, General Medicine, Tver State Medical Academy, Tver, Russia, M.D.
2015 - 2016, Bone Marrow Transplantation Fellow, City of Hope, Duarte, CA
2012-2015, Clinical Fellow, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN
2009-2012, Internal Medicine Residency, Hennepin County Medical Center, Minneapolis, MN
2023-present, Program Director, Hematopoietic Cell Transplantation and Cellular Therapy Fellowship, City of Hope, Duarte, CA
2016-present, Assistant Professor, Division of Leukemia, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA
Awards & Memberships
Memberships
Member, Cord Blood Advisory Group with Be the Match
Member, American Society of Hematology
Member, American Society of Clinical Oncology
Member, American Society for Blood and Marrow Transplantation
Publications
Aribi A, Salhotra A, Afkhami M, Munteanu A, Ali H, Aldoss I, Otoukesh S, Al Malki MM, Sandhu KS, Koller P, Arslan S, Stewart F, Artz A, Curtin P, Ball B, O'Hearn J, Spielberger R, Smith E, Budde E, Nakamura R, Stein A, Forman S, Marcucci G, Becker PS, Pullarkat V. WT1-mutated acute myeloid leukemia is sensitive to fludarabine-based chemotherapy and conditioning regimens. Leuk Lymphoma. 2023 Aug 3:1-11. doi: 10.1080/10428194.2023.2241096. Epub ahead of print. PMID: 37533373.
Akahoshi Y, Spyrou N, Hogan WJ, Ayuk F, DeFilipp Z, Weber D, Choe HK, Hexner EO, Rösler W, Etra AM, Sandhu K, Yanik GA, Chanswangphuwana C, Kitko CL, Reshef R, Kraus S, Wölfl M, Eder M, Bertrand H, Qayed M, Merli P, Grupp SA, Aguayo-Hiraldo P, Schechter T, Ullrich E, Baez J, Beheshti R, Gleich S, Kowalyk S, Morales G, Young R, Kwon D, Nakamura R, Levine JE, Ferrara JLM, Chen YB. Incidence, clinical presentation, risk factors, outcomes, and biomarkers in de novo late acute GVHD. Blood Adv. 2023 Aug 22;7(16):4479-4491. doi: 10.1182/bloodadvances.2023009885. PMID: 37315175; PMCID: PMC10440469.
El Jurdi N, Martens MJ, Brunstein CG, O'Donnell P, Lee SJ, D'Souza A, Logan B, Hong S, Singh AK, Sandhu K, Shapiro RM, Horowitz MM, Hamilton BK. Health-Related Quality of Life in Double Umbilical Cord Blood versus Haploidentical Marrow Transplantation: A Quality of Life Analysis Report of BMT CTN 1101. Transplant Cell Ther. 2023 Jul;29(7):467.e1-467.e5. doi: 10.1016/j.jtct.2023.04.009. Epub 2023 Apr 22. PMID: 37088401; PMCID: PMC10330136.
Amanam I, Yao J, Puing A, Tsai NC, Samuels D, Ngo D, Ho S, Ali H, Aribi A, Arslan S, Artz A, Htut M, Koller P, Salhotra A, Sandhu K, Nikolaenko L, Pawlowska A, Shouse G, Stein A, Marcucci G, Forman S, Nakamura R, Dadwal S, Al Malki MM. Use of monoclonal antibody therapy in hematologic patients with mild-to-moderate COVID-19: A retrospective single-center experience. Cancer Med. 2023 May;12(10):11248-11253. doi: 10.1002/cam4.5832. Epub 2023 Apr 20. PMID: 37081733; PMCID: PMC10242327.
Aldoss I, Afkhami M, Yang D, Gu Z, Mokhtari S, Shahani S, Pourhassan H, Agrawal V, Koller P, Arslan S, Tomasian V, Al Malki MM, Artz A, Salhotra A, Ali H, Aribi A, Sandhu KS, Ball B, Otoukesh S, Amanam I, Becker PS, Stewart FM, Curtin P, Smith E, Telatar M, Stein AS, Marcucci G, Forman SJ, Nakamura R, Pullarkat V. High response rates and transition to transplant after novel targeted and cellular therapies in adults with relapsed/refractory acute lymphoblastic leukemia with Philadelphia-like fusions. Am J Hematol. 2023 Jun;98(6):848-856. doi: 10.1002/ajh.26908. Epub 2023 Mar 16. PMID: 36880203.
Agrawal V, Pourhassan H, Tsai NC, Ngo D, Koller P, Malki MMA, Salhotra A, Ali H, Aribi A, Sandhu KS, Arslan S, Ball B, Otoukesh S, Amanam I, Artz A, Singh D, Becker PS, Stewart FM, Smith EP, Curtin P, Stein AS, Marcucci G, Forman SJ, Nakamura R, Pullarkat V, Aldoss I. Post-Transplantation Sinusoidal Obstruction Syndrome in Adult Patients with B Cell Acute Lymphoblastic Leukemia Treated with Pretransplantation Inotuzumab. Transplant Cell Ther. 2023 May;29(5):314-320. doi: 10.1016/j.jtct.2023.01.017. Epub 2023 Jan 19. PMID: 36682470.
Salhotra A, Sandhu KS, Yang D, Mokhtari S, O'Hearn J, Tegtmeier B, Al Malki MM, Abella J, Meguro A, Dickter J, Khambapati S, Spielberger R, Artz A, Forman SJ, Smith E, Nakamura R, Dadwal SS. Association of pre-transplant vancomycin resistant enterococcus colonization status on long-term outcomes of allogeneic-hematopoietic cell transplantation. Bone Marrow Transplant. 2023 Mar;58(3):346-348. doi: 10.1038/s41409-022-01895-0. Epub 2022 Dec 16. PMID: 36526805.
Salhotra A, Sandhu K, O'Hearn J, Ali H, Nakamura R, Modi BG. A critical review of belumosudil in adult and pediatric patients with chronic graft-versus-host disease. Expert Rev Clin Immunol. 2023 Mar;19(3):241-251. doi: 10.1080/1744666X.2023.2152330. Epub 2022 Nov 30. PMID: 36440483.
Ponce DM, Alousi AM, Nakamura R, Slingerland J, Calafiore M, Sandhu KS, Barker JN, Devlin S, Shia J, Giralt S, Perales MA, Moore G, Fatmi S, Soto C, Gomes A, Giardina P, Marcello L, Yan X, Tang T, Dreyer K, Chen J, Daley WL, Peled JU, van den Brink MRM, Hanash AM. A phase 2 study of interleukin-22 and systemic corticosteroids as initial treatment for acute GVHD of the lower GI tract. Blood. 2023 Mar 23;141(12):1389-1401. doi: 10.1182/blood.2021015111. PMID: 36399701; PMCID: PMC10163318.
Aldoss I, Khaled SK, Wang X, Palmer J, Wang Y, Wagner JR, Clark MC, Simpson J, Paul J, Vyas V, Chien SH, Stein A, Pullarkat V, Salhotra A, Al Malki MM, Aribi A, Sandhu K, Thomas SH, Budde LE, Marcucci G, Brown CE, Forman SJ. Favorable Activity and Safety Profile of Memory-Enriched CD19-Targeted Chimeric Antigen Receptor T-Cell Therapy in Adults with High-Risk Relapsed/Refractory ALL. Clin Cancer Res. 2023 Feb 16;29(4):742-753. doi: 10.1158/1078-0432.CCR-22-2038. PMID: 36255386.
- Bachanova V, Sandhu KS, Cao Q, Burke M, Verneris M, Weisdorf DJ. Prognostic Impact of CD20 Expression in Patients with Acute Lymphoblastic Leukemia Treated with Allogeneic Stem Cell Transplantation. Blood. 2011 May 12;117(19):5261-3
- Majhail NS, Brunstein CG, Warlick ED, Shanley R, Sandhu KS, Wagner JE, Weisdorf DJ. Reduced Intensity Allogeneic Hematopoietic Cell Transplantation in Older Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome: Comparable Outcomes With Unrelated Umbilical Cord Blood and HLA-identical Sibling Donors. Bone Marrow Transplant. 2012 Apr;47(4):494-8
- Sandhu KS, Brunstein C, Defort T, Bejanyan N, Arora M, Warlick E, Weisdorf D, Ustun C. Umbilical Cord Blood Transplantation Outcomes in Acute Myelogenous Leukemia/Myelodysplastic Syndrome Patients Aged ≥70 Years. Biol Blood Marrow Transplant. 2016 Feb;22(2):390-3
- Aldoss I, Yang D, Aribi A, Ali H, Sandhu K, Al Malki MM, Mei M, Salhotra A, Khaled S, Nakamura R, Snyder D, O'Donnell M, Stein AS, Forman SJ, Marcucci G, Pullarkat V. Efficacy of the combination of Venetoclax and hypomethylating agents in relapsed/refractory acute myeloid leukemia. Haematologica. 2018 Sep;103(9):e404-e407
- Aldoss I, Dadwal S, Zhang J, Tegtmeier B, Mei M, Arslan S, Al Malki MM, Salhotra A, Ali H, Aribi A, Sandhu K, Khaled S, Snyder D, Nakamura R, Stein AS, Forman SJ, Marcucci G, Pullarkat V. Invasive fungal infections in acute myeloid leukemia treated with venetoclax and hypomethylating agents. Blood Advances. 2019 Dec 10;3(23):4043-4049.
- Srinagesh HK, Özbek U, Kapoor U, Ayuk F, Aziz M, Ben-David K, Choe HK, DeFilipp Z, Etra A, Grupp SA, Hartwell MJ, Hexner EO, Hogan WJ, Karol AB, Kasikis S, Kitko CL, Kowalyk S, Lin JY, Major-Monfried H, Mielke S, Merli P, Morales G, Ordemann R, Pulsipher MA, Qayed M, Reddy P, Reshef R, Rösler W, Sandhu KS, Schechter T, Shah J, Sigel K, Weber D, Wölfl M, Wudhikarn K, Young R, Levine JE, Ferrara JLM. The MAGIC algorithm probability is a validated response biomarker of treatment of acute graft-versus-host disease. Blood Advances 2019 Dec 10;3(23):4034-4042.
- Mei M, Tsai N, Mokhtari S, Al Malki M, Ali H, Salhotra A, Sandhu K, Khaled S, Smith E, Snyder D, Marcucci G, Forman S, Pullarkat, Stein A, Aldoss, Nakamura R. Long-Term Outcomes of Allogeneic Hematopoietic Cell Transplant with Fludarabine and Melphalan Conditioning and Tacrolimus/Sirolimus as Graft-versus-Host Disease Prophylaxis in Patients with Acute Lymphoblastic Leukemia. Biology of Blood and Marrow Transplantation. 2020 Aug;26(8):1425-1432.
- Salhotra A, Yang D, Mokhtari S, Malki MMA, Ali H, Sandhu KS, Aribi A, Khaled S, Mei M, Budde E, Snyder D, Cao T, Spielberger R, Marcucci G, Pullarkat V, Forman SJ, Nakamura R, Stein A, Aldoss I. Outcomes of Allogeneic Hematopoietic Cell Transplantation After Salvage-Therapy With Blinatumomab in Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia. Biology of Blood and Marrow Transplantation. 2020 Feb 5. pii: S1083-8791(20)30062-8.
- Sandhu KS, Dadwal S, Yang D, Mei M, Palmer J, Salhotra A, Al Malki M, Aribi A, Ali H, Khaled S, Forman SJ, Snyder D, Nakamura R, Stein AS, Marcucci G, Aldoss I, Pullarkat V. Outcome of Allogeneic Hematopoietic Cell Transplantation after Venetoclax and Hypomethylating Agent Therapy for Acute Myelogenous Leukemia. Biology of Blood and Marrow Transplantation. 2020 Dec;26(12): e322-e327.
- S.C. Gergoudis, Z. DeFilipp, U. zbek, K.S. Sandhu, A.M. Etra, H.K. Choe, C.L. Kitko, F. Ayuk, M. Aziz, J. Baez, K. Ben-David, U. Bunworasate, I. Gandhi, E.O. Hexner, W.J. Hogan, E. Holler, S. Kasikis, S.M. Kowalyk, J.Y. Lin, P. Merli, G. Morales, R. Nakamura, R. Reshef, W. Rsler, H. Srinagesh, R. Young, Y.B. Chen, J.L.M. Ferrara, J.E. Levine. Biomarker-guided preemption of steroid-refractory graft-versus-host disease with a-1-antitrypsin, Blood Advances. Dec 2020; 4 (24): 6098–6105.